experiment was to illustrate electrophilic aromatic substitution by synthesizing p-nitroanilide (as well as ortho) from acetanilide by nitration. The para form was separated from the ortho form based on solubility properties using recrystallization techniques. Synthetic equations: Physical Properties & Hazards of Reagents/Products: (all taken from Sigma-Aldrich website) Acetanilide MM = 135.16 g/mol Melting point = 113-115°C Hazards: acute toxicity Sulfuric acid MM = 98.08 g/mol Boiling
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Therapy‚ Physiotherapy & Speech therapy services with in an NHS region. The region covers a General Acute hospital‚ Rehab hospital as well as an Elderly hospital In your capacity as a Financial Controller you are requested to explain what mechanisms would you adopt to: (a) Ensure regular monitoring of the business (b) alert respective internal stakeholders particularly when an adverse variance seems probable Articulate also which information would you make use of to achieve (A) and (b)
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segment .The first parts would consider the introduction which would talk about the concept of religion and that of social control. In the same section I would also consider the position of Ross as stating that religion is a more social control mechanism that enacted laws of society. The second and third part would look at how these religious elements would or can inform crime prevention and last the conclusion respectively. By definition religion has been defined by many scholars in various
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The RIP protocol is a dynamic‚ distance-vector routing protocol used in local and wide area networks. This is an implementation of single routing metric (hop count) which measures the best route distance between the source and a destination network RIP. RIP is an interior gateway protocol (IGP) which means that it performs routing within a single autonomous system (AS). RFC1058 and RFC1723 are two formal documents that define this protocol. RIP uses UDP port 520 for route updates and sending messages
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an organic laboratory‚ to carry out syntheses that are discussed in the lecture course‚ and to familiarize you with the principles employed in identifying a simple organic compound. Occupational Health and Safety Notices The Elements 1. Nitration of acetanilide 2. Hydrolysis of p – nitroacetanilide and thin layer chromatography 3. Separation of a three – component mixture by extraction 4. Completion of experiments from day 1 to 4 5. NMR workshop 6. Sandmeyer Reaction: Preparation of p-chloronitrobenzene
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Paracetamol - a curriculum resource Frank Ellis RSeC ROYAL SOCIETY OF CHEMISTRY Paracetamol - a curriculum resource Compiled by Frank E llis Edited by Colin Osborne and Maria Pack Designed by lmogen Bertin Published by the Royal Society of Chemistry Printed by the Royal Society of Chemistry Copyright 0 Royal Society of Chemistry 2002 Registered charity No. 207890 Apart from any fair dealing for the purposes of research or private study‚ or criticism or review‚ as permitted under
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Abstract This experiment is about the synthesis of 3-nitrobenzaldehyde through nitration. The nitration of benzaldehyde is an example of an electrophilic aromatic substitution reaction‚ in which a proton of an aromatic ring is replaced by a nitro group. Many aromatic substitution reactions are known to occur when an aromatic substrate is allowed to react with a suitable electrophilic reagent‚ and many other groups besides nitro may be introduced into the ring. Although the reaction produced a low
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Recrystallization Abstract: Technical grade aniline was reacted with acetic anhydride to give acetanilide a dark brown color‚ due to the presence of impurities. Crystallization of the crude product from water was combined with decolorization with activated carbon‚ furnished pure acetanilide as white flakes‚ melting point 112-115°C‚ yield 70.3%. Experimental: 2 grams of technical grade aniline and 15ml water were placed in a 125ml Erlenmeyer flask. Then‚ 2.5ml of acetic anhydride was
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20711 Lab Experiment: Nitration of Bromobenzene Introduction: The chemical reaction of nitration consists of a nitro group being added to or substituted in a molecule. Nitration can basically be carried out by a mixture of concentrated nitric acid and sulfuric acid; this mixture is useful to obtain the active nitronium ion. Electrophilic aromatic substitution is a method used when a functional group is needed to be substituted on to an aromatic compound. In the nitration‚ nitronium ion acts as
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Preparation of 4-bromoaniline Introduction Aromatic compounds tend to undergo electrophilic aromatic substitutions rather than addition reactions. Substitution of a new group for a hydrogen atom takes place via a resonance-stabilized carbocation. As the benzene ring is quite electron-rich‚ it almost always behaves as a nucleophile in a reaction which means the substitution on benzene occurs by the addition of an electrophile. Substituted benzenes tend to react at predictable positions. Alkyl groups
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