Executive Summary Merck & Company has been presented with an opportunity to invest $30 million for the purchasing rights of an obesity and high cholesterol lowering drug‚ KL-798 from Kappa Labs. Based on the expected probabilities of success through each product-development phase for this new drug‚ as well as the costs involved‚ the net present value of the project is -$1.16 million and is therefore recommended that Merck passes on the investment. Sensitivity analysis also show that adjusting
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Merck & Co.‚ Inc. Case If one hold a key to resolve a very serious problem‚ one has a responsibility to put an effort to make it happen‚ at least try one’s best. In this case‚ river blindness disease was a very serious problem‚ and Dr. Vagelos was the one who could make a decision as to whether the research and development of a human version of ivermectin should be carried on‚ then it was his responsibility to pursue it. Caused by a parasitic worm carried by a tiny black fly‚ the disease
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Greek/Latin Roots Acer‚ Acid‚ Acri- Bitter‚ Sour‚ Sharp Examples: Acerate : Shaped like a needle. Acidity: Quality of sourness Acrimonious: Nagging and bitter The acerate building towered over me. The acidity of vinegar made him vomit. The wife grew acrimonious. Anni‚ Annu‚ Enni- Year Examples: Annuity: Money paid annually Biennial: Occurrence of two years Triennial: Occurrence of three years His annuity was a good six figures.
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Color blindness or color vision deficiency is the inability or decreased ability to see color‚ or distinguish color differences‚ under normal lighting conditions. Color blindness affects many people in a population. "Color blind" is a term of art; there is no actual blindness but there is a fault in the development of one or more sets of retinal cones that perceive color in light and transmit that inform ation to the optic nerve. Symptoms like those of color blindness can also be produced by physical
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Questions for the Merck Case Create a decision tree for Merck. The 2 leftmost branches would identify the alternatives related to licensing Davarink (specifically license versus not to license). Next‚ if Merck decides to pursue license‚ they go into phase I which results in a success‚ or failure. Phase I success is followed by phase II where Merck has the opportunity to develop the drug to treat depression alone‚ weight loss alone‚ or both‚ or contemplate phase II failure. Finally phase
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INATTENTIONAL BLINDNESS Inattentional blindness‚ also known as perceptual blindness‚ is the phenomenon of not being able to see things that are actually there. This can be a result of having no internal frame of reference to perceive the unseen objects‚ or it can be the result of the mental focus or attention which cause mental distractions. The phenomenon is due to how our minds see and process information. Closely related to the subject of change blindness‚ it is an observed phenomenon of the
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Ethical Blindness Guido Palazzo • Franciska Krings • Ulrich Hoffrage Received: 1 June 2010 / Accepted: 22 November 2011 Ó Springer Science+Business Media B.V. 2011 Abstract Many models of (un)ethical decision making assume that people decide rationally and are in principle able to evaluate their decisions from a moral point of view. However‚ people might behave unethically without being aware of it. They are ethically blind. Adopting a sensemaking approach‚ we argue that ethical blindness results
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Colour blindness is a very well known deficiency that affects approximately 8% of the population worldwide (Fluck 2006). People who are colour blind are not technically blind‚ they have a decreased ability to identify colours and in the most extreme cases‚ not able to see colours at all. The technical term for being colour blind is achromatopsia which means the inability to see any colours at all. However‚ most people are only colour deficient and not fully color blind therefore they can be classified
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10th Grade‚ English Sight or Blindness? Throughout the play‚ Oedipus Rex‚ Sophocles makes several references about sight and blindness. Even though Tiresias is a blind man‚ he is the one that knows the truth and is insinuating that Oedipus doesn’t want to face it. Oedipus develops into a character blinded by all the greatness that Thebes has given him. The oracle prophesized by the gods is the main reason that led him to become the tragic hero of this play. First and foremost‚ Sophocles’
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Deaf Blindness Most people assume that a deaf blind child is someone who is not able to hear or see. “Our country’s special educational law defines deaf-blindness as the combination of the visual and hearing impairment” (“Deaf Blindness”). These two impairments make the person lose his or her communication skills‚ developmental and educational needs. The National Consortium on Deaf-Blindness observes that the key feature of deaf-blindness is that the "combination of losses limits access to
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