Use of SDS-PAGE/Western Blot Techniques as Diagnostic Tools for Equine Medical Conditions SDS-PAGE Overview Electrophoresis is commonly used to separate proteins using an applied electrical field. SDS-PAGE separates proteins by molecular weight‚ using sodium dodecyl sulfate (SDS; also known as lauryl sulfate) to denature them and a discontinuous polyacrylamide gel as a sieving matrix. The net charges of folded proteins are not dependent upon molecular weight. Rather‚ charge is determined by
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Explain your answer. -To compete with Vidastat and grab back the market share -To gain back doctors’ support 4. As a marketing student‚ how would you respond to this pricing issue with the worsening economic in Southeast Asia in mind? Do you think Merck implemented the right strategy by lowering its price‚ thereby exposing itself to criticism from its customers? -Maintain the price and increase the quality of Zocor -Focus on research and development (R&D) of side effects Conclusion 1) One of
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TENTATIVE SYLLABUS for A&B 495‚ Section 002 BUSINESS ADMINISTRATION CAPSTONE TR‚ 2-3:50pm; CAB214‚ Winter 2007 Instructor: Dr. Bruce Walters‚ CAB 129B‚ Ph: 257-3499‚ E-mail: bwalters@cab.latech.edu Office Hours: M-F‚ 9-10am‚ 1-2pm‚ & by appointment Required Texts: Thompson‚ Strickland‚ & Gamble‚ Crafting and executing strategy‚ 15th ed.‚ McGraw-Hill/Irwin; supplemental handouts Students pursuing a degree in the CAB must earn a “C” or better in all courses in their major area‚ and they
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We all will one day face the reality of growing older. There are many aspects of this change that will affect us in a large way. According to the Merck Manual of Health and Aging‚ 1.5% of Americans are 85 or older. This research states that the number of people 100 years or older could rise from 1 out of 5‚578 in the year 2000‚ to 1 out of 472 in the year 2050. It brings out that women have a longer life expectancy than men‚ among people aged 65 and older in the year 2000‚ there were 70 men for
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Summary: In March 1989 Merck and Johnson & Johnson joined hands to form the joint venture Johnson & Johnson/Merck Consumer Pharmaceuticals Company (JJM). JJM produces Pepcid which belongs to a class of drugs known as H2 receptor antagonists. This class of drugs reduces stomach acid secretion and revolutionized the treatment for ulcers and heartburn. Pepcid is well known for its quick heartburn relief has a stable market position but is still behind the leading competitors Tagamet (from SmithKline
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(Mayo Clinic). There is still no cure‚ but there are treatments that help reduce or control the weakness in the voluntary muscles. Myasthenia gravis can occur in anybody‚ but it is more common in younger women from ages 20-40 and older men from 50-80(Merck Manual). MG might have something to do with sex and age. In addition‚ this disease is actually a chronic disease which means it will keep occurring and be long lasting. MG is not genetic or inherited‚ but MG does have a lot to do with age‚ gender‚
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of Novartis since 1999‚ and is Chief Executive Officer of Novartis since the merger that created Novartis in 1996. The global pharmaceutical industry tops $600 billion in sales annually‚ where Novartis’ top three competitors are Johnson & Johnson‚ Merck‚ and Pfizer. Novartis’ sales over the past 5 years have steadily increased from $23.1 billion to $36.7 billion. Major factors affecting investment potential include heightened competition from generic drug makers‚ unprecedented pricing pressure from
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Abstract A natural polyphenolic compound Quercetin was extracted from widely available and consumed plant Allium fistulosum which has shown promising chemo preventive and chemotherapeutic activities in cancer. In this study‚ quercetin is encapsulated and loaded onto PLGA (Poly lactic glycolic acid) microspheres using double emulsification methodology for improving its efficiency in cancer therapy. Quercetin is extracted and purified using chromatographic and nuclear magnetic resonance (NMR) techniques
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at the University of Kansas‚ do not support mandatory vaccination of children based on the grounds of ethics behind immunization companies. For example‚ the Gardasil vaccination. Merck‚ the company behind Gardasil‚ is pushing Gardasil to be a mandatory vaccination. “Experts predict that Gardasil sales could net Merck between $1.6 and $2 billion dollars annually (Smith‚ 2006). Making the vaccine mandatory‚ which requires injecting three doses per individual at a price of approximately $360 per dose
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Making TLC Plates from Bulk TLC Silica Gels Many TLC users prefer to use pre-coated TLC plates‚ but others because of their special needs‚ or because they need special additives or a special thickness‚ coat their own TLC plates. This paper is a quick review of what is needed for the process. Initial instructions for plate coating: If reproducible plates are needed‚ then the user should invest in a coating device from Camag or Desaga (addresses below). The devices consist of a tray that holds
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