METABOLIC SYNDROME LEARNING OBJECTIVES At the end of lecture students should know – Definition of Metabolic Syndrome – Visceral obesity is an indicator of the syndrome and an independent marker for CVD – Current and some potential future treatment options. METABOLIC SYNDROME CONCEPT (Not New) • 1923 - Kylin first to describe the clustering of hypertension‚ hyperglycemia‚ hyperuricemia • 1936 - Himsworth first reported Insulin insensitivity in diabetics • 1965 - Yalow and Berson
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Content METABOLIC ENGINEERING 2 AIMS OF METABOLIC ENGINEERING 2 CHARACTERISTICS OF METABOLIC ENGINEERING 2 IMPORTANCE OF METABOLIC ENGINEERING 3 THE METHODS 3 REQUIREMENTS FOR METABOLIC ENGINEERING 4 RE-CONSTRUCTING THE MODEL 4 TERMINOLOGY 4 METABOLIC FLUX ANALYSIS (MFA) 4 METABOLIC CONTROL ANALYSES 6 DATABASES 7 IN SILICO EXPERIMENTS 8 APPLICATION AREAS OF METABOLIC ENGINEERING 8 METABOLIC ENGINEERING OF GEOBACILLUS THERMOGLUCOSIDASIUS…………………………………9
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Running head: METABOLIC SYNDROME Metabolic Syndrome James Doucette College of Western Idaho Abstract Metabolic syndrome is an emerging diagnosis in the medical field that has effects on patient care. Becoming familiar with it and having it become a common part of patient care will‚ if used appropriately will increase the lives of those who have become affected with or are at risk of becoming diagnosed with metabolic syndrome. Metabolic syndrome is a constellation of risks
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GREAT METABOLIC CHALLENGE Metabolism is a series of vital biochemical processes that take place in order to sustain life. During a marathon run‚ the individual relies on the breakdown of carbohydrates and lipids‚ in order to provide energy release in the form of Adenosine Triphosphate (ATP). This essay will focus on the role of mobilization and structures of both carbohydrates and lipids in the production of ATP. Mobilization of Carbohydrates When carbohydrates are consumed during a meal‚ catabolism
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Resting metabolic rate can vary with age independently from body mass changes in the Colorado potato beetle‚ Leptinotarsa decemlineata. Abstract A study was done by Saija Pironine‚ leena Lindstrom‚ and Anne Lyytinen in the Journal of Insect Physiology‚ to investigate the age dependence of resting metabolic rate in Colorado potato beetle (Leptinotarsadecemlineata) from adult emergence until age 10 days. In their hypothesis they expected to see a bell shaped pattern in metabolic rate with adult age
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Analysis-Final Plot and Paramters 1. 1.2507 2. 0.685 3. 0.685 4. 17.811 Data Analysis-Mass Specific Metabolic Rate 1. 1.2507 2. -0.315 3. -0.316 4. 17.811 Review Questions: 1. Under what conditions does 02 consumption provide a good estimate of the metabolic rate? Under Aerobic conditions. 2. What factors should be considered when the metabolic rate measured is to be a reliable measure of the basal metabolic rate? The animal must be resting. The animal must be in its thermoneutral zone. The animal
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The Great Metabolic Race Metabolism comprises of a vital set of biochemical reactions that all living organisms require to sustain life. For a marathon runner‚ their physiological response to strenuous exercise depletes both their fats and carbohydrate storage in order to supply energy in the form of Adenosine Triphosphate (ATP). ATP is the energy form that the human body uses for biological processes such as movement and synthesis of biomacromolecules. In regards to running a marathon‚ the athlete
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Introduction: Basal Metabolic Rate has been defined as the minimum amount of energy needed by an animal to maintain the basic functions of survival (such as breathing). Several factors including age‚ gender‚ weight‚ and exercise affect the BMR. "BMR increases with increasing muscle tissue" therefore‚ exercising will enhance BMR while with increasing age‚ BMR is reduced (Scott‚ 2008). Also gender differences exist between males and females; it has been shown that males have higher BMRs
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BMR (basal metabolic rate) Basal metabolic rate (BMR)‚ and the closely related resting metabolic rate (RMR)‚ is the amount of energy expended while at rest in a neutrally temperate environment‚ in the post-absorptive state (meaning that the digestive system is inactive‚ which requires about twelve hours of fasting in humans). The release of energy in this state is sufficient only for the functioning of the vital organs‚ the heart‚ lungs and kidneys and the rest of the nervous system‚ intestine‚
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The Great Metabolic Race Organisms are constantly undergoing various chemical reactions and pathways that enable for them to maintain life. These pathways are part of metabolism‚ involving catabolism (break down of organic nutrients for extraction of useful) and anabolism (energy dependent conversion of small precursor molecules in complex molecules); some of which are energy coupled to provide energy efficiency. This intermediate coupling is due to the “energy currency” within the body‚ known as
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