Formulations and Formulation Development Pre-Formulation Studies Incompatibilities encountered in drug multi-component combinations and /or Drugexcipient Compatibility. Pharmaceutical Formulation Additives‚ Containers and Closures. Manufacturing and Quality control of Solid Dosage forms‚ Semi-Solid Dosage forms‚ Liquid Dosage forms‚ Sterile Dosage forms‚ Metered Dosage forms (Aerosols) Study of principles‚ Production techniques‚ Pilot batch studies‚ Scale-up Studies‚ Transfer of technology
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4-aminobenzoate was recovered. For the recovery of benzoic acid‚ NaOH was added to convert the carboxylic acid of the benzene to the water-soluble benzoate anion‚ which dissolves in the aqueous NaOH solution while the non-acidic impurities remain in the organic phase. After separating the aqueous layer into an Erlenmeyer flask‚ the basic solution of sodium benzoate was acidified by washing it with HCl and filtering it with DI water. This compound had to most significant recovery of 46. 3%‚ but some may
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Preparation of an Acetic Acid Ester Abstract: 14.1 g of octyl acetate were synthesized from the esterification process using 20.0 ml of acetic acid and 17.9 g of n-octanol. The theoretical yield was 23.8 g of octyl acetate. The percent yield was 59.2%. The purification of the final ester was confirmed by boiling point (186-199°C) and infrared index (nD=1.419). It was a colorless liquid that had a slight fragrance of orange and indescribable chemicals. The Infrared spectra confirmed ester
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LOVELY PROFESSIONAL UNIVERSITY DEPARTMENT OF MANAGEMENT SUMMER TRAINING REPORT ON DOCCUMENTATION OF A PHARMACEUTICAL PRODUCT “RANITIDINE” AND DOSSIER FORMULATION FOR EXPORT TO PHILLIPINES [pic] | [pic] | |
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drinks in 1950 when research showed there were harmful effects to humans (“The Origins of Soda”). There are several toxic ingredients in today’s chemistry‚ that are causing health concerns. Ingredients such as: Phosphoric Acid‚ Citric Acid‚ Sodium Benzoate‚ High-Fructose Corn Syrup‚ Caffeine‚ Caramel
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September 30‚ 2012 Experiment 5‚ Preparation of Synthetic Banana Oil Introduction: This experiment prepares synthetic banana oil (isopentyl acetate) through the Fisher esterification method by combining isopentyl alcohol with acetic and sulfuric acid then heating the mixture under reflux for an hour. Esterification is a chemical reaction in which two reactants (an alcohol and an acid) form an ester as the reaction product. Observations and Data: When the sulfuric acid was combined
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laboratory manual‚ which was 0.4 g‚ it can be seen that the procedure performed better than the current percent yield may illustrate. The most plausible reason for this expected value may be from the nature of the reaction performed here‚ the Fischer Esterification tends to act as an equilibrium‚ and as such it is prone
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AIMS At the end of the experiment‚ students should be able to synthesise pure aspirin using chemical tests such as esterification and recrystallization independently and to also find out the melting point range of aspirin using melting point determination. INTRODUCTION Aspirin‚ which is also known as acetylsalicylic acid‚ is one of the commonly used and widely found in any drugstore or pharmacy. Its properties make aspirin a well-rounded drug that reduces inflammation and fever and also relieves
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Synthesis of Banana Flavor via Fischer Esterification Patricia Faye R. Agnila‚ Joan Karla M. Alvaran*‚ Micaela Isabel N. Arellano‚ and Denzel Nicho T. Armendares Department of Biological Science‚ College of Science‚ University of Santo Tomas‚ Manila‚ Philippines Abstract This experiment is conducted to exhibit the synthesis of banana
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Chemistry of Spices This page intentionally left blank Chemistry of Spices Edited by Villupanoor A. Parthasarathy Indian Institute of Spices Research Calicut‚ Kerala‚ India Bhageerathy Chempakam Indian Institute of Spices Research Calicut‚ Kerala‚ India and T. John Zachariah Indian Institute of Spices Research Calicut‚ Kerala‚ India CABI is a trading name of CAB International CABI Head Office Nosworthy Way Wallingford Oxfordshire OX10 8DE UK Tel: +44 (0)1491 832111 Fax:
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