Daclizumab (Biogen Idec and Abbott Biotherapeutics Corp.) is a humanized mAb acting as a blocker of the α-subunit (CD25) of the high-affinity IL-2 receptor [19]. IL-2 is secreted by activated lymphocytes and stimulates production of other proinflammatory cytokines while it is also involved in lymphocytic proliferation. Daclizumab was initially approved for the prevention of renal allograft rejection as part of a combination regimen and evidence was progressively accumulated showing that this drug
Premium Immune system Cancer Protein
Account Management Case Study AGENDA FOR THE PRESENTATION AM’s Performance Measurement Framework Seller’s Classification Seller Evaluation Framework Challenges Faced – Sellers Prespectives Account Management Initiatives to Increase Sales [SNAPDEAL Actions] Initiatives to Increase Sales [Sellers Actions ] Proposed structure - “AM – Sellers” alignment Account Manager Number of Sellers Handled Rishi 272 Omi 445 Akki 42 Sid 16 Vinod 5 Account Manager High Revenue Account Sid
Premium Sales Revenue Customer service
Apple‚ Inc. A Case Study in External Communication Executive Summary Background: On June 25‚ 2010 Apple released the iPhone 4. With its sleek‚ new‚ stainless steel frame design‚ thousands of people rushed to buy Apple’s latest gadget. Apple and its partner carriers received 600‚000 pre-orders for the iPhone 4s in the first 24 hours‚ making it the largest number of pre-orders Apple had received in a single day for any device up to that time. By the end of the month‚ Apple had sold over 1.7
Premium Apple Inc. Communication Mobile phone
in groups of equipment called bays‚ hence the assumed age of assets per bay is the same. Asset condition is determined based on an Asset Health Index derived from condition assessments and reliability data (MTBF‚ MTTF‚ MTTR) which is missing in this case. Typically a Health Index Score between 50% and 60% means an asset needs to be monitored more closely with a potential change in proactive maintenance approach. For 50% lower a risk assessment is required and if it is a high risk assets‚ it be put
Premium Management Wind power Marketing
| Corporate Sustainability Management | Case Study Analysis: Nike‚ Inc. and Sweatshops | | | | | Ethics refer to what is defined as right or wrong in the morality of human beings and social issues are matters which could directly or indirectly affect a person or many members of a society. In this case study‚ Nike has been accused of subjecting employees in their subcontracted factories overseas to work in inhumane conditions for low wages. The CEO and cofounder of Nike lamented
Premium Minimum wage Wage Employment
of powerhouse products that will take everyday life beyond the ordinary—beyond imagination. R&D at Samsung Innovation is crucial to Samsung’s business. As new technologies are being constantly introduced to the market‚ speed is essential for remain-ing competitive in today’s digital era‚ and new markets have to be pioneered continuously.Through the interplay of creative‚ imaginative people; a global R&D network; an organization that encourages collaboration and cooperation among business
Premium Research and development Innovation Research
Magnolia Therapeutic Solutions Case Study Whittni Summerlee University of Phoenix BSHS/373 Financial Management in Human Services Frieda Flowers January 24th‚ 2010 Magnolia Therapeutic Solutions Case Study Magnolia Therapeutic Solutions is a well known nonprofit that provides psychotherapy for clients with Post Traumatic Syndrome Disorder (PSTD). Magnolia contributed several hours of intensive help to the victims of 911. In return NYC gave the organization a large grant
Premium Management Risk management Non-profit organization
Solution to Case 01 Financial Analysis and Forecasting Growing Pains Questions 1. Since this is the first time Jim and Mason will be conducting a financial forecast for Oats’ R’ Us‚ how do you think they should proceed? Which approaches or models can they use? What are the assumptions necessary for utilizing each model? Jim and Mason should begin their planning with a reasonable sales forecast. The sales forecast ought to be based on clearly stated assumptions about future economic
Premium Balance sheet Revenue Financial ratios
Sunflower Incorporated case study Overview: Sunflower Inc. is a large distribution company with over 5000 employees that functions as a bureaucracy‚ which needs to formalize its pricing and purchasing practices. The company purchases and distributes snack foods to retail stores across North America. Sunflower has one corporate office and the company is divided into twenty-two regions. Each region operates as an autonomous small business‚ which consists of its own leadership. characterized
Premium Management Small business
Case Study – Thomas Motor Company John Thomas is the Managing Director of the Thomas Motor Company. He succeeded to the position of Managing Director after his father’s untimely death in May 1978. Martin Thomas‚ the founder of the Thomas Motor Company‚ Started off as an apprentice mechanic in a suburban area of Melbourne when he was only eighteen working as an assistant to Fred Luthans. Martin learnt all he knew about automechanics from him. He was a keen and enthusiastic learner and Luthans like
Premium Mechanics The Work