TITILE OF THE PROJECT pH SENSITIVE CHITOSAN DERIVATIVE POLYMERICS NANOPARTICLES AS DRUG CARRIER IN TARGETING COLON CANCER CELLS INTRODUCTION: Cancers area group of diseases characterized by uncontrolled growth of abnormal cells in tissues and its leading cause of death. To date‚ cancer caused 7.6 million deaths (around 13% of all deaths) around the world and this will projected to continue to rise to over 13.1 million deaths in 2030. Among this colon cancer arises when this uncontrolled cell
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. RESULTS PRESENTATION AND ANALYSIS Solver CPLEX‚ version 12.6‚ was used to run the mathematical model on a computer with an Intel Core i7 processor with 16GB of RAM. The maximum execution time was limited to 7‚200 seconds for each instance. When running instances with CPLEX it was possible to obtain results to measure the quality of the RAS metaheuristic solution. RAS was developed in C language and run on the same computer described before with a runtime limited to 7‚200 seconds. RAS metaheuristic
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Identification and characterization of Pierisin gene in P. napi The strategy was followed to amplify the Pierisin-6 gene was given in the supplementary Fig. 1. The mRNA of pierisin-6 gene was purified from the total RNA of fifth instar larvae of P. napi‚ the conserved region was amplified using gene specific primers (supplementary table-1)‚ cloned into pGEM®-T vector and sequenced. Further‚ 3’ and 5’ untranslated regions of pierisin-6 gene were identified by 3’/5’ RACE-PCR. The amplified cDNA sequence
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Turkistan Travels Sdn. Bhd. (MTT) found out the following; i. that the setup of subsidiary company under fraudulent circumstances ii. staff morale had been low iii. company being short of funds iv. the staff not being paid their salaries 2. Investigation by CFO‚ Ms. Goh had realized as per following; i. MTT only has provided annual audited financial report and there had been no other information revealed; and ii. No position or portfolio that catered to the monitoring of MTT or any of MTSB’s other
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For the treatment of cancer most of the drugs currently available but they have limited therapeutic potential because they are very toxic‚ expensive‚ highly inappropriate action in treating cancer‚ or having so many side effects like granulocytopenia‚ agranulocytosis‚ lymphocytopenia‚ alopecia‚ carcinogenicity or secondary cancer especially leukaemias and hyperuricaemia etc. Curcumin is one such natural herbal medicine‚ derived from the extraction of dried rhizome of turmeric or Curcumin longa‚
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QUESTION 1: Image you were a director of MTSB in 2006‚ what would be the steps you would taken to fulfill your fiduciary duties as a director. The steps MTSB have taken to fulfill the fiduciary duties as a director according section 6 of Companies Act‚ fiduciary duties of a director. Step 1 : Understanding about duties of director To carry out your duties as a director well‚ it is necessary for you to be fully aware of the duties and responsibilities expected of directors. Directors are fiduciaries
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to trail stock. As from MTT has a problem with the stock as there are short sales of stock which could be indentify by Sage as stock being release more than inventory and transaction will be prohibited from carrying out; while Excel would follow the transaction to be entered. This has shows that accounting software has an advantage over normal spreadsheet. Security Security of accounts is important which prevent pilfering of accounts data which would be of importance to MTT‚ such accounts and information
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An extract and clarifications of changes in rules and systems of Lovely Professional University (Applicable w.e.f. Session 2013-14) Lovely Professional University has always valued feedback from its different stakeholders – especially from students and teachers. We can boast of a formal system of feedback in the University which supplements the informal mechanisms for feedback on issues such as curriculum‚ pedagogy‚ evaluation and other rules and systems of the University. Feedbacks on some key
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This paper is the first to indicate antiemetic activity of the methanolic extract compositions of A. julibrissin flowers and its protective effect on mitochondria disruption induced by retching in brain of the young chickens. Nausea and vomiting are the symptoms of drug side effects‚ different disease and defenses responsive against poisoning. Recently‚ extensive researches have led to use of medicinal plants as a safe and reliable source of drugs with low or lack of toxicity and side effects [22
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Relationship between Mental Toughness and Mindfulness Joshua Perez Australian Catholic University Relationship between Mental Toughness and Mindfulness The psychological strength of an individual is just as important in the repertoire of an elite athlete as well as being physically strong and having high physiological capabilities. In some cases‚ the mental toughness of an athlete is what separates elite athletes from the rest of his/her competitors. According to McCanny (2014)‚ the area
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