Drug Metabolism Prof. Patrick Davis Basic Medicinal Chemical Principles PHR 143M Fall-08 Importance of Drug Metabolism • The basic premise: Lipophilic Drugs --> Hydrophilic Metabolites (Not Excreted) (Excreted) • Water soluble => increased renal excretion -anddecreased tubular re-absorption of lipophilics. Importance of Drug Metabolism CH 3 CH 2OH CHO COOH OH O C 2H 5 Δ1-THC PC=6000 - O C O O HO OH COO OH OH Excreted Form O C 2H 5
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2. Compare the development of lymphocytes with other formed elements. B lymphocytes develop in red bone marrow‚ T lymphocytes develop in red bone marrow and mature in the thymus; the other formed elements develop in red bone marrow 3. What is erythropoiesis? Which factors speed up and slow down erythropoiesis? Erythropoiesis is the process by which red blood cells (erythrocytes) are produced. If you lose a lot of blood‚ erythropoiesis will speed up; anemia can cause erythropoiesis to slow down
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“ Ageing is a continuous‚ complex‚ and dynamic process that begins with birth and ends with death. And unless we die in our early years‚ each of us will grow old and experience the effects of the ageing process”. (Pirkl‚ 2009). The ageing process and why changes have taken place in the last fifty years. This report discusses the ageing process and why changes have taken place in the last fifty years. The ageing process is a change in an organism overtime and can be referred to as a multidimensional
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Exposure Mode Chart Icon/Letter Name What It Does Do This This exposure mode makes the background out-of-focus‚ if it’s possible to do so. This eliminates distracting backgrounds‚ and can make the subject stand out from the background. The lens opening (aka f/stop or aperture) is the iris-like opening in the lens. When using this exposure mode‚ Head Portrait the camera selects a large lens opening‚ such as f/4. A large lens opening has a large opening‚ but the number is small. For example‚ f/4
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How Does Flight Crew Fatigue Affect Flight Operations? Introduction: In this report‚ I will be writing about the effects of flight crew fatigue‚ and how it has the ability to affect flight operations. Operating a flight as a commercial airline pilot‚ it can become very tiring which develops into a problem as it starts to affect their performance. Background Information The aviation industry requires a 24/7 operation resulting in shifts that are
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Human Physiology Lab Special Senses Cutaneous Senses and Vision September 24/26‚ 2012 Our bodies are capable of sensing a wide spectrum of stimuli. We are consciously aware of some of the information our bodies perceive‚ but much of the information that is sensed is beyond our consciousness. Receptors responsible for perception of stimuli are found in many places: skin‚ eyes‚ ears‚ mouth‚ blood vessels‚ lungs‚ brain—frankly‚ every cell in the body has sensory receptors. These receptors are
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Recruitment and Placement MGMT 2203 Les Kauer May 2‚ 2012 Overview At BMG they are having a little problem with a recent hire and the process that landed that employee in that position. The VP of HR is dealing with an upset hiring manager about a new hire that is not going well. The VP wants her to understand that it is not HR’s fault that the person was eventually chosen. She on the other hand wants him to admit fault. The back and forth gets a little heated and ultimately no solution
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LABORATORY REPORT RENAL PHYSIOLOGY INTRODUCTION: The kidneys‚ which maintain the purity and constancy of our internal fluids‚ are perfect examples of homeostatic organs. They regulate the chemical content the pH and osmotic pressure of the blood. Kidneys filter gallons of fluid from the bloodstream. They then process this filtrate‚ allowing wastes and excess ions to leave the body in urine while returning needed substances to the blood in just the right proportions. Factors that affect urine
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nurses can become victims of the continuing stress of meeting the often overwhelming needs of patients and their families resulting in compassion fatigue (Kim‚ 2013). Boyle (2011) defines compassion fatigue as contemporary label affixed to the concept of personal vicarious exposure to trauma on a regular basis. For health professionals‚ compassion fatigue arises when providers have close interpersonal contact with a suffering patient and their emotional boundaries become blurred to the point that
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Running head: COMPASSION FATIGUE 1 Compassion Fatigue: A Concept Analysis A Paper Submitted in partial fulfillment of the requirements for NU 506 Theoretical Foundations of The practice of nursing is synonymous with the concepts of empathy‚ compassion‚ nurturing‚ and caring. In the last two decades‚ a global nursing shortage has developed‚ leading to a phenomenon in nursing never seen before; the delivery of nursing care without nurturing. Increased workloads‚ higher patient acuity‚
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