A muscle is a group of cells called fibers‚ and are generally quite big. One muscle fiber has a large amount of myofibrils‚ which are muscle proteins in the shape of cylinders. These myofibrils contain two different types of filaments‚ which run along the axis of the fiber in hexagonal patterns. The two types of filaments are thick and thin filaments. Every thick filament is surrounded by six thin filaments. Both thick and thin filaments are attached to a structure called the Z-line. The Z-line runs
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hysioEx 9.0 – Exercise 2: Skeletal Muscle Physiology Name: Chart 1: Latent Period Results Voltage Active force (g) Latent period (msec) 0.0 0.00 XXXXXXXXXX 3.0 1.04 XXXXXXXXXX 4.0 1.32 2.40 6.0 1.65 2.40 8.0 1.81 2.40 10.0 1.81 2.40 Chart 2: Effect of Stimulus Voltage on Skeletal Muscle Contraction Voltage Active force (g) 0.0 0.00 0.2 0.00 0.8 0.02 1.0 .15 1.5 .43 2.0 .66 2.5 .87 3.0 1.64 3.5 1.19 4.0 1.32 4.5 1.42 5.0 1.51 5.5 1.59 6.0 1.65 6.5 1.70 7.0 1.74 7
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to study the effects of Ca2+ channel blockers in muscle contraction by observing the effects of injecting it in frog legs. Since calcium channel blockers‚ block the Ca2+ channels‚ inhibiting the calcium from binding to troponin‚ which exposes the myosin binding site‚ we hypothesize that the muscle fibers will not be able to contract to the same extent and therefor contraction will be
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NPB 101L Final Exam Review Lab 2 – Skeletal Muscle 1. Describe basic setup a. What was manipulated? Intensity‚ frequency b. What was measured? Twitch tensions c. What concepts were investigated? i. Frog‚ sciatic nerve‚ gastroc‚ d. What was investigated? i. Effects of stimulus frequency and intensity on contraction-the more intensity‚ the higher the twitch tension. The more freq- the more twitch tension (By ~4.0pps we start to see summation of the twitches and by ~15pps we see no single twitches
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The length-tension relationships represent an important part in the function of skeletal muscle. When skeletal muscle is stimulated‚ passive tissue rapidly changes into dynamic tissue which can produce force. Furthermore‚ during this process‚ the length of muscle may decrease‚ increase‚ or remain the same. Moreover‚ the amount of power a muscle can produce depends on its length‚ velocity and stimulation Powers & Howley (2015). Muscle velocity and stimulation are normally in a constant when creating
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Answer: B Reference: Contraction and Relaxation of Skeletal Muscle Degree of Difficulty: Medium 8. Tunnel-like extensions of the sarcolemma into the muscle fiber are A) sarcomeres. B) myofibrils. C) transverse tubules. D) tropomyosin. E) myosin cross bridges. Answer: C Reference: Skeletal Muscle Tissue
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sarcolemma—carries action potential 3. Triad __1__ part of sarcoplasmic reticulum—stores calcium ions 7. Myofibrils consist of contractile proteins called myofilaments. Name the two types and what they’re composed of: Thick filaments composed of myosin (red) Thin filaments composed of actin (blue) 8. Arrangement of myofilaments. Give the letter name of each band: Dark band __A__ band Light band __I__ band Match two definitions with each band: __I__ contains only thin filaments __A__
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318). A microtubule‚ which is made of proteins located in cytoskeleton‚ is one of three filaments that is long‚ hollow stiff tube and responsible for intracellular transport. This transport system is driven by kinesin and dynein in microtubules and myosin in actin filaments‚ which are called motor proteins. (Gross‚ Tuma‚ Deacon‚ Serpinskaya‚ Reilein‚ & Gelfand‚ 2002‚ p. 855). To understand how those movements along microtubules can make the rapid colour change possible‚ it is necessary first to find
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Surprisingly‚ Wnt-1 and Wnt-3a overexpression up-regulated BMP-4‚ and inhibition of BMP-4 by shRNA or recombinant Noggin protein rescued the myogenic inhibitory effect of Wnt-1 and Wnt-3a. Importantly‚ Wnt-3a or BMP-4 recombinant proteins promoted slow myosin heavy chain expression during myogenic differentiation of fetal myoblasts. Conclusions: These results demonstrate a novel interaction between canonical Wnt and
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Self-renewal and differentiation are fundamental stem cell fate decisions‚ which are essential for normal tissue development‚ homeostasis‚ and repair actin cytoskeleton and Rho-GTPases‚ mediate downstream signal transduction Serum response factor (SRF) and yes-associated protein (YAP) are two examples of mechano-sensitive transcription factors‚ which have recently been implicated in epidermal and mesenchymal stem cell differentiation Lab notes: Passive processes: transport driven by
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