ethnicities. However‚ Acne Free contains a cleanser‚ toner‚ and moisturizer each have 2.5% benzoyl peroxide‚ and the Clean and Clear Advantage Acne Control Kit contains a cleanser with 10% benzoyl peroxide‚ moisturizer with 0.5% salicylic acid and a spot remover with 2% salicylic acid. Products within each kit contain different ingredients and are both made by different companies. Below are comparisons on how each product leaves the skin feeling‚ variation in cost‚ and a description of the
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SYNTHESIS OF THE PHARMACEUTICAL ASPIRIN (ACETYLSALICYLIC ACID) AIM: The aim for this experiment was to synthesise a small amount of aspirin with salicylic acid as the starting product and sulphuric acid as the catalyst. The product obtained from this reaction will be impure and will need to be purified. This will be done by recrystallization. We will then record the products’ melting point and calculate the yield in order to determine the degree of purity of the aspirin sample. Diagrammatic scheme
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Aspirin Background Aspirin Aspirin‚ or acetylsalicylic acid (ASA) is a salicylate drug‚ and is generally used as an analgesic (something that relieves pain without producing anaesthesia or loss of consciousness) for minor aches and pains‚ to reduce fever (an antipyretic)‚ and also as an anti-inflammatory drug. Aspirin works by prohibiting biological substances such as prostaglandins. Many different prostaglandins exist in the human body each serving a plethora of physical functions.
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(ACETYLSALICYLIC ACID) Aim: The aim of this experiment was to react salicylic acid with ethanoic anhydride to produce Aspirin. CH3CO)2O + HOC6H4COOH → CH3CO2C6H4CO2H + CH3COOH i Mass: 5g Volume: 7.5 cm3 Mass: 6.52g RMM: 138g/mol RMM: 180g/mol Moles: 5/138 = 0.0362 RMM: 102g/mol Moles: 0.0362 OBSERVATIONS – First‚ Ethanoic acid was added to the salicylic acid which resulted in a cloudy solution. When adding a few drops of concentrated sulfuric acid‚ which acted as
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leaves were also found to contain salicylic acid. Two Italians‚ Brugnatelli and Fontana‚ had in fact already obtained salicin in 1826‚ but in a highly impure form. Johann Buchner‚ professor of pharmacy at the University of Munich‚ isolated a tiny amount of bitter tasting yellow‚ needle-like crystals‚ which he called salicin (1828). Henri Leroux had improved the salicin extraction procedure to obtain about 30g from 1.5kg of bark (1829). An additional source of salicylic acid was found in 2835 by the German
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things that it can help with. Aspirin is known as Acetylsalicylic acid (ASA) is a Salicylate. Salicylates are organic acids from plants that people for hundreds of years have been used for pain reducing. Salicylic acid irritates the stomach when consumed so German scientist Felix Hoffman suggested ASA as an alternative. Aspirin is made when Acetic Anhydride reacting with Salicylic acid to produce Acetylsalicylic acid and Acetic acid (diluted vinegar). Aspirin is in millions of home today and in America
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1874‚ Dresden‚ Germany- Salicylic acid was first made and sold as a pain-killer‚ but it caused severe irritation of the mouth‚ gullet and the lining of the stomach. Salicylic acid (2-Hydroxybenzoic acid) 1875- Chemists made sodium salicylate for doctors to try on patients. It was found to have
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3.1 Mass of dried‚ recrystallized aspirin: 1.62g 3.2 Percent yield: 51.75% yield 3.3 Temperature range: 138.2 – 140.0°C 3.4 Appearance: Fine needle like white crystal Introduction Aspirin or acetylsalicylic acid is acquired from salicylic acid‚ which is mild and nonnarcotic analgesic. It helps to remove the substance in the body that trigger pain‚ fever and inflammation. The father of modern medicine was Hippocrates‚ who lived sometime between 460 B.C and 377 B.C. Hippocrates
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efficiency and purity. The purpose of our experiment was to synthesize acetyl salicylic acid (aspirin) and then determine the relative purity of the synthesized sample by observing the melting point temperature range. The procedure performed in our experiment involved chemically reacting salicylic acid and acetic anhydride in order to form acetyl salicylic acid. The limiting reactant in this chemical reaction was salicylic acid‚ with acetic anhydride present in excess in order to react with any water
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acetylsalicylic acid (aspirin) by creating a reaction between acetic anhydride and salicylic acid. This was be accomplished through the use of recrystallization. Acetic anhydride and salicylic acid are mixed together‚ and then acidified by the addition of a few drops of concentrated sulfuric acid‚ which catalyzed the reaction. The percent yield is calculated to determine the effectiveness of the reaction in preparing the desired product (aspirin). The limiting reactant of the equation was salicylic acid. After
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