NAME LAB TIME/DATE _ Microscopic Anatomy and Organization of Skeletal Muscle Skeletal Muscle Cells and Their Packaging into Muscles 1. Use the items in the key to correctly identify the structures described below. g; perimysium c; fascicle Key: a. b. c. endomysium epimysium fascicle fiber myofibril myofilament perimysium sarcolemma sarcomere sarcoplasm tendon 1. 2. 3. 4. 5. 6. 7. connective tissue ensheathing a bundle of muscle cells bundle of muscle cells contractile unit of muscle
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Mitochondria 7. Myofibrils 8. Cytosol (Sarcoplasm) 9. Sarcomere a. Z lines b. M line c. A bands d. I bands e. H zone 10. Myofilaments a. Actin i. Troponin ii. Tropomyosin b. Myosin C. Neuromuscular Junction - See IP-CD: Muscular System: Neuromuscular Junction section 1. Motor neuron (axon terminal) 2. Motor end plate of a myofiber (sarcolemma‚ nuclei & mitochondria) 3. Synaptic cleft 4. Neurotransmitter vesicles and neurotransmitter molecules (ACh) D. Motor
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Myasthenia is believe not to be hereditary or contagious. Neuromuscular junction Neuron and muscle are not connected to each other. There is a small gap between them. This is called neuromuscular junction. Neuron (from the brain or spinal cord) will passed action potential through axon of motor neuron to an axon terminal. Sodium ion (Na+) and calcium ion (K+) are higher concentration outside than from the inside of the muscle and neuron. Na+ and K+ want to go inside but blocked by these channels
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A chiropractor is someone who is a health care professional focused on the diagnosis and treatment of neuromuscular disorders. Neuromuscular disorders are many diseases and ailments that impair the functioning of the muscles‚ either directly‚ being pathologies of the voluntary muscle‚ or indirectly‚ being pathologies of nerves or neuromuscular junctions. Their treatments are natural‚ whole-body‚ drug-free treatments of for a variety of conditions. Chiropractors want to help reduce the pain the patient
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contraction. The neuromuscular junction is the point that the skeletal muscle and neurons come in contact. How Muscles & Bones Interact The muscles and bones in our body are joined by a tough connective tissue called tendons. As you move your bones‚ your muscles follow along. Skeletal muscles work in opposing pairs: when one contracts‚ the other one relaxes. Skeletal muscles generally remain in state of partial contraction (even when your legs are straight). Neuromuscular Junction Impulses from motor
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relaxation of skeletal muscle bring about body movements. These body movements are voluntary and facilitated by the somatic nervous system. Near contact between somatic motor neurons and the muscle fibers are referred to as neuromuscular junctions. It is at the neuromuscular junctions that neurons are able to transmit a signal to the muscle fibers causing muscle contractions. In order to understand physiological mechanisms of skeletal muscle tissue‚ including twitch recruitment‚ length-tension relationship
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Diseases of the Muscular System There are over 650 muscles in the human muscular system. Each muscle has a specific role to perform. These muscles help us talk‚ walk‚ sit‚ run‚ eat‚ move about‚ hold things‚ and most important the continuous pumping of the heart muscles keeps us alive. Muscular system diseases cause many problems in the human body‚ that affects the mobility and functioning of various parts of the body. The list is very long as there are number of disorders that affect the human body
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Rabies life cycle. According to the World Health Organization the death rate of rabies exceeded 50‚000 every year globally considering unreported cases1. Rabies virus is associated with bats mostly‚ and it mainly exists in rabid animal saliva1. Rabies can enters a body through a direct contact such as bite transmission‚ a bite from a rabid animal‚ or nonbite transmission‚ saliva or central nervous system tissue touches an open wound or scratch on the body1. These are the most common ways that allows
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Myasthenia gravis Overview: Myasthenia Gravis is an autoimmune disorder of the post-synaptic neuromuscular junction whose pathogenesis consists in an attack on antibody-mediated At the acetylcholine receptor site on the postsynaptic membrane of the neuromuscular junction. Causes: Characteristics of the disease are muscle weakness and fatigue. The pattern of symptoms is typically fluctuating; it is more pronounced at night and improves with rest. Initial symptoms include: ptosis‚ diplopia or blurred
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Botulism is a dangerous neuroparalytic illness caused by a botulinum toxin that is a product of the Clostridium botulinum bacteria. This toxin invades neuromuscular junctions by blocking the release of acetylcholine and results in lack of muscle contraction. According to Centers for Disease Control and Prevention‚ “There are three main kinds of botulism: foodborne botulism‚ infant botulism‚ and wound botulism. Foodborne botulism occurs when a person ingests the toxin within food that leads to illness
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