PHYSIOLOGY Transmembrane receptors composed of excitable G-proteins‚ which cross the cell membrane and link selectively with extra cellular ligands are called adrenoceptors. They are also termed as α-2 Adrenoceptor agonists α-2 adrenergic receptors. Three α-2 isoreceptors - α-2a‚ α-2b and α-2c of adreno receptor bind α-2 agonists and antagonists with similar rapport and share an amino acid composition homology of roughly 70 to 75%. The efficacy of sub receptor specific agonists that constrains deleterious
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Neurophysiology Study Guide 1. Define "equilibrium potential". Why is the resting potential closer to the potassium equilibrium potential (EK+) than the sodium potential (ENa+)? The equilibrium potential is the point at which the force exerted on an ion by electrostatic and concentration gradient forces are balanced‚ and there is no net movement of that ion. The resting potential is closer to EK+ than ENa+ because the cell membrane is more permeable to
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Adrenergic medications affect the four receptors‚ a1‚ a2‚ B1 and B2. The sympathetic nervous system triggers the secretion of epinephrine and norepinephrine. Epinephrine is a hormone and norepinephrine functions as a hormone and neurotransmitter. First we will take a look at the Alpha 1 receptors. These Alpha 1 receptors cause vasoconstriction of vascular smooth muscles. They are located on the post synaptic membranes of effector organs‚ such as on gastral and urinary sphincters. Some are located
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metabolized or excreted ELIMINATION Drug at site of action Pharmacologic effect Pharmacodynamics Toxicity Efficacy PHARMACOLOGY Pharmacodynamics Actions of drug on the body Specific to a drug/ class of drugs • Interaction with target sites (receptors/enzymes) • Effects at site of action • Dose-response relationship • Reduction in symptoms • Modification of disease process • Unwanted/side effects • Drug interactions • Inter- and intra-patient differences Pharmacokinetics Actions of body on
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Neurophysiology Lab Report Anatomy & Physiology Lab Report Exercise 3 Activities 1-4‚ 8 By Laurence Blake 2/27/12 A. Objective I. Activity 1-4: Eliciting a Nerve Impulse • Investigate what kinds of stimuli stimulate action potential. II. Activity 8: Nerve Conduction Velocity • Determine and compare the conduction velocities of different types of nerves. B. Introduction I. Activity 1-4: Eliciting a Nerve Impulse • In this experiment‚ we
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Neurophysiology has been a subject of study since as early as 4‚000 B.C. In the early B.C. years‚ most studies were of different natural sedatives like alcohol and poppy plants. In 1700 B.C.‚ the Edwin Smith surgical papyrus was written. This papyrus was crucial in understanding how the ancient Egyptians understood the nervous system. This papyrus looked at different case studies about injuries to different parts of the body‚ most notably the head. Beginning around 460 B.C.‚ Hippocrates began
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EXERCISE 3: Neurophysiology of Nerve Impulses ACTIVITY 1: The Resting Membrane Potential Answers 1. The nervous system contains two general types of cells: neuroglia cells and a. nerves. b. cell bodies. c. neurons. d. nephrons. 2. The resting membrane potential of the neuron in this lab under the control conditions was _______ mV. 3. True or False: For most neurons‚ the concentration of Na+ and K+ ions inside and outside the cell are the primary factors that determine the resting membrane
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conducted by the lab group was to figure out which parts of the human body had the most touch receptors. The proposed hypothesis stated that touch receptors would have a greater concentration if the specific body part has a function relating to the touch receptors. For instance‚ fingers and facial features should have the most and parts of the neck‚ hand‚ wrist‚ and ear should have less touch receptors than the other parts because the former have greater function that relates to human senses. In
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Moorpark College Human Physiology Name: _________________________________ EXERCISE 3 Neurophysiology of Nerve Impulses Laboratory Report Answer the following questions. (3 points each). 1. What is the difference between membrane irritability and membrane conductivity? Membrane irritability is the ability to respond to a stimuli and convert it in to nerve impulses. Membrane conductivity is the ability to transmit that impulse that is created by membrane irritability. 2
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if ether will have an effect on eliciting an action potential which I believe that it will make it difficult. Curare is a well known plant extract that South American Indians used to paralyze their pray. It blocks synaptic transmission by preventing the flow of neural impulses from neuron to neuron (Laboratory Manual). I believe that the effect of curare eliciting an action potential will lead to curare not being able to act on an action potential because it will block and slow down the stimulation
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