Experiment #1 – Aromatic Nitration The purpose of this lab is to convert toluene to nitrotoluene through the process of aromatic nitration. This is done by electrophilic aromatic substitution. The aromatic organic compound‚ toluene‚ is reacted under mild conditions with an electrophile‚ the nitronium ion‚ resulting in a product of nitrotoluene. Failure to use mild conditions may result in polynitration. Different reaction conditions were studied to understand the effect of nitrating agent
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SCIENCE(HONS)BIOCHEMISTRY YEAR 1 SEMESTER 1 UDEC1164 ORGANIC CHEMISTRY Name: Cheong Wai See Student ID: 1404057 Practical Group: 1 Title of Experiment: Name of Tutor: Dr. Mohammod Aminuzzaman Date: 24 February 2016 Tiltle: Nitration of Methyl Benzoate Objectives: -To prepare methyl-3-nitrobenzoate from nitration of methyl benzoate by electropilic aromatic substitution. -To calculate the percentage yield and get the melting point of methyl-3-nitrobenzoate. Introduction: Benzene contains compounds have special properties
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Electrophilic Aromatic Substitution: The Nitration of Toluene Abstract This industrially important reaction of EAS: The Nitration of Toluene exhibits how the attack of a nitronium ion would give out major and minor products at different positions of toluene. This is an electrophilic substitution mechanism. Mixture of concentrated sulphuric and nitric acid will produce a nitronium ion‚ which will attack ortho-‚ meta- and para- positions at Toluene. (Mechanism at appendix). Introduction/Procedure
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Nitration of Methyl Benzoate Introduction: Nitration is an example of an electrophile aromatic substitution reaction‚ where nitro (NO2) group is being substituted for a hydrogen on an aromatic compound. This is achieved by the formation of the nitronium ion by protonation of nitric acid from sulfuric acid. The zirconium ion is a strong electrophile and can react with aromatic compound such as Methyl benzoate to form an arenium ion intermediate. The arenium ion is then depronated to reform
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in the presence of an electrophile‚ aromatic compounds will undergo electrophilic aromatic substitution. In this type of reaction‚ two π electrons from the aromatic ring serve for the ring to act as a nucleophile and attack an electrophile. For nitration‚ this nucleophile is NO2+‚ which is produced by reacting nitric and sulfuric acids. After the nucleophile adds‚ the ring has lost aromaticity. Therefore‚ the deprotonated acid in solution can pull off a hydrogen from the same carbon that the nitro
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Title: Nitration of Methyl Benzoate Objective: To prepare methyl-3-nitrobenzene from nitration of methyl benzoate. Results and calculations: Density = 1.094 g/ml = Mass of methyl benzoate = 1.094 g/ml x 2.8 ml = 3.0632 g no. of mol of methyl benzoate = = 0.022499 mol 1 mol of methyl benzoate produced 1 mol of methyl m-nitrobenzene. Therefore‚ 0.022499 mol of methyl benzoate produced 0.022499 mol of methl
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Lab 6: Electrophilic Aromatic Substitution(1) Nitration of Methyl Benzoate(2) Synthesis of 1‚4-Di-t-butyl-2‚5-dimethoxybenzene byFriedel-Crafts Alkylation of 1‚4-DimethoxybenzenePurpose1)To carry out the nitration of methyl benzoate‚ and then identify the major product formed (position at which nitro-group substitution takes place) by thin-layer chromatography (TLC)‚ the percent yield and the melting point range. 2)To synthesize 1‚4-Di-t-butyl-2‚5-dimethoxybenzene by Friedel-Crafts Alkylation of
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Lab 8- nitration of Methyl I Benzonate Date of experiment: INTRODUCTION: The nitration of methyl benzoate is an example of an electrophilic aromatic substation reaction. In the experiment the electrophile was the nitronium ion and the aromatic compound was methyl benzoate and with addition of nitrating solution Methyl 3-nitrobenzoate was the product. Methyl benzoate Methyl 3-nitrobenzoate MATERIALS AND METHODOLOGY: The procedures for this experiment
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Loreta Grazhees TA: Titas Friday 11:50 - 3:55 February 9‚ 2018 Nitration Of Toluene When reacting Toluene with (NO2+) the end goal is to generate an ortho-‚ para-‚ and/or meta-nitrotoluene. This lab will help guide you in the direction to predict the regioselectivity and activation vs. deactivating powers of the nitro-group. Gas Chromatography will be used to analyze compounds that can be vaporized without being decomposed. GC is also used to check the purity of a substance‚ and separating the
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level‚ duly recognized both by the Commission and Higher Education (CHED) and TESDA. Back in 2010 our institution enrollment succeeded to a percent of one hundred and fifty. Our computer facilities intends only into a very limited units so that our Lab supervisor easily maintain and create schedules for students who has a computer subjects. By this time‚ Speed Computer College again increased by staggering a percent of two hundred enrollees. One of the main problems of Speed Computer College
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