D24BT8 Structural Biology Essay - What is the future of structural genomics in academia and industry? Cera Wong April 3‚ 2013 Structural genomics (SG) programs were formed by development of structure biology in large scale. Targets were selected from a specific genome‚ topologically similar types of proteins or protein families. (REF: Maksymilian) SG programs have developed more accurate and efficient methodologies on structure determination over the last decade (REF: Maksymilian)‚ where many
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http://www.ejchem.net ISSN: 0973-4945; CODEN ECJHAO E-Journal of Chemistry 2012‚ 9(2)‚ 980-987 Design‚ Synthesis and Docking Studies of a Novel Ciprofloxacin Analogue as an Antimicrobial AGENT S.JUBIE*‚ R. KALIRAJAN and PAVANKUMAR YADAV‚ Department of Pharmaceutical Chemistry J.S.S. College of Pharmacy‚ off campus - JSS University‚ Mysore jubiejawahar@gmail.com Received 31 July 2011; Accepted 4 October 2011 Abstract: The carboxylic acid group of ciprofloxacin was modified and amino mercapto triazole
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The Michael addition is a reaction named after Arthur Michael. Discovered in 1887‚ this is a carbon-carbon bond making reaction. The result of the Michael addition is a 1‚4 addition of a nucleophile to an alpha‚ beta-unsaturated carbonyl carbon compound. A 1‚4 addition is also commonly referred to as a conjugated addition. Another result of this reaction is a 1‚2 addition of a nucleophile. Some of the common attacking nucleophiles used in this reaction are enolates. Enolates‚ a negatively charged
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trans amino acid gave complete bond angles‚ distances‚ and computer stereograms. Afterwards‚ both the cis and the trans amino acids approached a boat conformation through bicyclic scheme; which proves the evaluation of the nuclear magnetic resonance (NMR) data. The pyrrolidine ring of both the acids has all four carbons in a plane‚ whereas the nitrogen atom and the cyclopropyl carbon are relocated to the same side of the plane. In this matter‚ the
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University of Maryland‚ College Park Department of Chemistry and Biochemistry CHEM 231: Organic Chemistry I‚ Fall 2014 The Highlights Bonnie Dixon TA: Courney Love Office: CHM 2130 email: bdixon1@umd.edu email: clove@umd.edu When/Where: Lecture MWF 9 a.m. – 10 a.m. in CHM 1407 Discussion T/H at 12:30 pm‚ 2 pm‚ and 3:30 pm in the CHM 1228 Course Materials: Organic
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MSA University Faculty of Pharmacy Organic Chemistry Department Spectrometry Course Code: PC 222 Name: Ghazal Mhd Bassam Bakieh ID: 136909 Name: Christine Botros Mihail Bishay ID:124509 Name: Yaman Mhd Fawaz Hawasly ID: 137215 DR/ Hala I-Infrared spectrometer and sampling techniques Spectrophotometer Spectrophotometry in chemistry is a quantitative measure of the reflection or transmission of material properties as a function of wavelength. It is more
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aMicroscale Synthesis of Isopentyl Acetate (Banana Oil) Objective: Carried out the microscale synthesis of isopentyl acetate by direct esterification of acetic acid and isopentyl alcohol. This was an acid catalyzed Fischer esterification. Both extraction and distillation were employed to obtain a pure product. IR spectroscopy and gas chromatography were used to determine purity of the final product. Reagents: * Compound: | * MW (g/mol): | * MP (°C): | * BP (°C): | * Density (g/mL):
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Experiment #1 Nucleophilic Aromatic Substitution of 2‚4-dinitrochlorobenze Name: Anouk Deck-Leger Student I.D: 9380868 Date performed: September 13th‚ 2010 Due Date: September 20th‚ 2010 Introduction: The company DNCB produces large amounts of 2‚4-dinitrochlorobenzene and they sell this product to treat against warts and severe and chronic hair loss. It can also be used as an alternative treatment for HIV. The supervisor notices an excess amount of m-aminobenzoic acid stored away which
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Abstract The goal of the experiment was to isolate and purify the unknown D liquid and solid by using its acidic and basic characteristics in a chemically active extraction then to identify the unknowns by analyzing the physical properties on IR and NMR spectrums. The neutral solid was purified through recrystallization and the melting point range was determined to be 47.5oC to 48.9oC. The basic liquid was purified with simple distillation and the boiling point of 135oC was concluded. Through the analysis
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dissolved in 15 mL of chloroform and an excess of cold ether (~32 mL) was added to the solution. The polymer precipitated as a white solid. It was washed with methanol‚ dried in desiccator and stored protected from light. The polymer was characterized by NMR and IR
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