"Nucleophile" Essays and Research Papers

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    My life

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    chiral center? Mark its chiral center on the structure with an asterisk. 8. Give the IUPAC names for the following compounds: (b) ClCH2CH2CH2CH(OH)CH3 (c) CH3CH2CH=CBrCH2CH3 would attract electrophile or nucleophile? Give examples of (i) nucleophiles and (ii) electrophiles. 10. Classify the reactions below: (a) CH3CH2CH=CHCH3 + Br2  CH3CH2CHBrCHBrCH3 (b) CH3CH(OH)CH3 + KOH(alc.)  CH3CH=CH2 + KBr + H2O (c) CH3CH2CH2OH + KMnO4  CH3CH2COOH (d) CH3CH2CHBrCH3

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    Guaifenesin

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    Synthesis and Isolation of Expectorant Guaifenesin By: Ben DuBose Dr. Cossey 3361L Abstract The purpose of this experiment was to isolate and synthesize Guaifenesin. Isolation was performed with the use of two Guai-Aid Tablets‚ each of which contained 400mg of pure Guaifenesin. Reflux‚ a technique used to heat a mixture without evaporating the solution‚ was used to synthesize Guaifenesin through a Williamson Ether Synthesis reaction with an SN2 mechanism. Introduction

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    SYNT 0719 – Brominating Alkenes OBJECTIVE The purpose of this lab will be to brominate trans-stilbene by using acetic acid and pyrimidium tribromide by refluxing the mixture. To test the purity of product I will take the melting point which should be around 240 ºC along with a flame test which should be green-blue. CHEMICAL PROPERTIES TABLE See Attached Lab Notebook Copies REACTION MECHANISM In this lab we used multiple techniques to complete and verify the bromination of trans-stilbene

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    bromide. The nucleophile in the experiment is bromide ion (Br-) while the leaving group is water. [pic] Purification of the product was then obtained by extraction. The principle of extraction as a purification method was based on the difference in solubility between impurities and product. Identify of the product (1-bromobutane) can be confirmed by carrying out sodium iodide in acetone test. The test involves displacement of bromide by iodide. Since iodide is strong nucleophile which can displace

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    Chase Sigler Summary

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    Chase Sigler‚ a senior double major in chemistry and human biology‚ recently presented the chemistry research he has been working on for the last three semesters at a conference hosted by the American Chemical Society. Jerry Easdon‚ professor of chemistry‚ said around sixteen thousand people typically attend the ACS conference. Close to two thousand of those in attendance are undergraduate‚ Easdon said and “many of them are presenting their senior research at a poster session‚ just like Chase did

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    Grignard Reagent Lab

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    cycloalkyl‚ or aryl halide and magnesium metal in dry ether. The reaction is shown below in figure 1. Figure 1: Formation of a Grignard reagent The Carbon bonded to the metal is both a strong nucleophile and base. The Carbon with the carbanion character can participate in nucleophile reactions

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    Organic Lab 7

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    substitution‚ which is when a nucleophile replaces the leaving group in the substrate. In this lab‚ the hydroxyl group of t-butyl alcohol is replaced by a chlorine atom. The reaction proceeds through an SN1 mechanism (Weldegirma 38-41). “A nucleophile is any neutral or uncharged molecule with an unshared pair of electrons. In the substitution reaction‚ the nucleophile donates an electron pair to the substrate‚ leading to the formation of a new bond to the nucleophile‚ while breaking the existing

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    Title: Relativities of Alkyl Halides in Nucleophilic Substitution Reactions Introduction: The purpose of this lab was to perform a comparison of relative reactivities of various alkyl halides with two different reagents‚ sodium iodine in acetone and silver nitrate in ethanol. (Below are the reaction equations). We used different substrates‚ which were primary‚ secondary‚ and tertiary. These substrates included 2-bromobutane‚ 2-bromo-2-methylpropane‚ 1-bromobutane ∞-Bromotoluene‚ bromobenzene

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    Ashley Droddy CHM 235LL-Monday‚ 3/19/2012 & 3/26/2012 Part A: Dehydration of 1-butanol & 2-Butanol/Part B: Dehydrobromination of 1-Bromobutane & 2-Bromobutane Abstract The objective of this experiment is to successfully perform a dehydration of 1-butanol and 2-butanol‚ also dehydrobromination of 1-bromobutane and 2-bromobutane to form the alkene products 1-butene‚ trans-2-butene‚ and cis-2-butene. The dehydration reactions react under and acid-catalysis which follows an E1 mechanism

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    Grignard Reaction: Synthesis of Triphenylmethanol Hai Liu TA: Ara Austin Mondays: 11:30-2:20 Abstract: In this experiment‚ phenylmagnesium bromide‚ a Grignard reagent was synthesized from bromobenzene and magnesium strips in a diethyl ether solvent. The Grignard reagent was then converted to triphenylmethanol‚ a tertiary alcohol with HCl. The reaction for phenylmagnesium bromide was: The reaction for Grignard to triphenylmethanol was: In the formation of the Grignard reagent

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