associated with increased deposition of matrix proteins in the myocardium. The expansion of the cardiac interstitial space in absence of significant cardiomyocyte loss is “reactive interstitial fibrosis” and the formation of scar in response to myocardial infarction is called “reparative fibrosis” [10‚ 46]. Increased deposition of endomysial and perimysial collagen leads to interstitial fibrosis in fibrotic heart (Figure 5). Increased collagen deposition in adventitia of intramural coronary arterioles
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(FDA) for its cholesterol drug Niaspan. In order to receive an indication from the FDA‚ a drug company must present two successful studies with the intended outcome. Niaspan has the FDA indication to raise HDL-C‚ reduce secondary non-fatal myocardial infarction‚ and regression of atherosclerosis in combination with a bile acid resin. In a recent study (cite) patients taking Niaspan demonstrated regression of atherosclerosis in combination with statin‚ a popular cholesterol treatment agent. Abbott
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anterior fascicular block‚ previous anterior _____(s/l cervical) myocardial infarction. Neck had no bruits‚ no _____. Lungs are clear. Heart: Single‚ first‚ and secondary sound without murmurs or gallops. Abdomen: No _____‚ and _____ enlargement of his aorta. Extremities has goods pulses with no edema. ASSESSMENT _____ I think the patient certainly can go ahead with his hip replacement surgery. I see no evidence of recurrent myocardial ischemia or _____. He does have some conduction to lay on his
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many decades and is characterized by lesion formation and luminal narrowing of the arteries. Atherosclerosis is the most common disease of modern times. In symptomatical situations‚ arteriosclerosis can be obvious like coronary heart disease‚ myocardial infarction‚ peripheral arterial occlusion disease. The disease caused by narrowing of the artery and a transient ischemia. Foam cell formation is one of the early events of atherosclerosis. Macrophages and smooth muscle cells (SMCs)‚ accumulate lipid
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Atherosclerosis is a disease affecting the arterial blood vessel and it is commonly referred to as a "hardening" or "furring" of the arteries. It is caused by the formation of multiple plaques within the arteries. Theses plaques begin to form when a vessel receives tiny injuries‚ usually at a point of branching. In turn these plaques gradually thicken and harden with fibrous material‚ cells‚ and other deposits‚ restricting the lumen (opening) of the vessel and reducing blood flow to the tissues‚
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24 25 Question 1 A CHF patient MOST likely has which of the following symptoms? diarrhea menorrhagia dyspnea euphagia 1 points Question 2 Which of the following is MOST likely to cause a stroke (by an occlusion) or a heart attack (infarction)? bruit varicose veins embolus mononucleosis 1 points Question 3 Which of the following abbreviations represents a dosing schedule? bpm bid PTT P 1 points Question 4 All of the following terms are matched with the correct
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or not.According to American Diabetes Association‚ fish oil significantly lowers the platelet aggregation and plasma triglyceride levels in diabetic patients. However‚ the clear effect of fish oil on insulin sensitivity ‚glucose tolerance‚myocardial infarction and death needs further investigations. 32
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had "aural and/or visual hallucinations".[10][11] His father was a river boat captain and by 1870 was a fertilizer manufacturer.[9] The elder Fish died in 1875 at the Sixth Street Station of the Pennsylvania Railroad in Washington‚ D.C. of a myocardial infarction. Fish’s mother then put him into Saint John’s Orphanage in Washington‚ where he was frequently treated sadistically. He began to enjoy the physical pain that the beatings brought.[12] Of his time at the orphanage‚ Fish remarked‚ "I was there
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limitations that can be lived with‚ these changes can also exacerbate many medical conditions. The elderly client I decided to evaluate‚ H.J.is a 76 year old african american female‚ that has a past medical history of chronic heart failure‚ myocardial infarction‚ hypertension‚ asthma‚ and renal mass. H.J.also has a past surgical history of a left mastectomy. She is retired and lives at home by herself and has one daughter. Some of her medical conditions are definitely effected by age as well as
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Situation: Two patients in their 70s present to the office at different times today‚ each with documented heart failure: one diastolic and the other systolic‚ and both are hypertensive. First‚ discuss the difference between systolic and diastolic heart failure‚ providing appropriate pathophysiology. ACEI/ARBs are the only medications prescribed for CHF that have been found to prolong life and improve the quality of that life. EXPLAIN the mechanism of action of ACEI/ARBs and how they affect morbidity
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