Predictive ability of Hypo1 To confirm the predictive power of Hypo1‚ each compound in training set was estimated through regression analysis method. The training set compounds classified into three groups: highly active IC50 < 100 nM‚ +++; moderately active IC50 < 100 nM _ 1‚000 nM‚ ++; inactive IC50 <1‚000 nM _ > 10‚000 nM‚ +. The estimated activities by Hypo1 pharmacophore model and experimental activities of 21 training set compounds presented in Table 1. The error value is calculated by the
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Sun (our star). 2) Briefly describe the major levels of structure (such as planet‚ star‚ galaxy) in the universe. Planet: (a) Orbits a star‚ (b) large enough for its own gravity to make it round‚ (c) has cleared most other objects from its orbital path. Sun: The star of our solar system. Star: Large‚ glowing ball of ignited gas that generates heat and light through nuclear fusion in its core. Galaxy: A great island of stars in space‚ containing a few hundred million or trillion stars
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g/cm3 Electronic Configuration: Diamond The carbon atom’s electronic configuration is believed to change from its ground state in diamond as follow: {draw:frame} Quantum-mechanical calculations indicate that greater overlap between orbitals results in a stronger covalent bond. The diamond structure represents a three-dimensional
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Bradon’s review Tuesday‚ September 23‚ 2014 1. 7:14 PM Explain the distinction between climate & weather. Using this concept‚ explain why an individual hurricane or summer heat wave is not in of itself proof of global warming? a. Climateis: a measure of the average pattern of variation in temperature‚ humidity‚ atmospheric pressure‚ wind‚ precipitation‚ atmospheric particle count and other meteorological variables in a given region over long periods of
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neutron? Increasing atomic number Elements on the periodic table are arranged in order of … # of electrons = # of protons What is the relationship between protons and electrons? 2 How many electrons can the first orbital or shell hold? 8 How many electrons can the second orbital or shell hold? 9/15 Atom An … has the same number of protons‚ neutrons‚ and
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FM Reading Response 1: Dave Gilbert’s “Space Harpoon Plan to Nail Orbital Garbage” Summary The article Space Harpoon Plan to Nail Orbital Garbage talks about this invention called a “space harpoon” that will eliminate only some of the space debris that is in earth’s low orbit. There is a lot of space debris that can cause future problems with the everyday technology that people use. An engineer‚ by the name of Jaime Reed‚ warns that the low-earth orbit may become unusable from the space junk if
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It was the middle of an away sophomore baseball game against DeWitt. My brother‚ Keegan‚ was up to bat. The pitch came‚ he swung and down he went. The baseball came off his bat and drilled him in the left eye. There was only one parent there‚ one of Keegan’s teammate’s dad. He drove Keegan to the hospital and called my parents. At the time‚ I was at a softball game working the scoreboard for the varsity West Delaware Hawks team. My mom called to tell me my grandma would pick me up when I was done
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Magnesium is one of the twenty-four elements on earth that are essential for life. It is vital in human metabolism; and if our magnesium levels are too high or too low‚ we could suffer from sleep disturbances. Magnesium is a very common element found on earth that is used for a lot of everyday items. Much of what we have today would not be possible without magnesium. Magnesium was originally discovered by Sir Humphry Davy in 1808‚ but some are not sure if he officially isolated the element. It was
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vehicle against the force of the Earth’s gravity. To place a satellite into orbit around the Earth‚ thrust must continue until the minimum altitude and orbital velocity have been attained or the launch vehicle will fall back to the Earth. Minimum altitude is rarely desirable‚ therefore thrust must continue to be generated to gain additional orbital altitude. The impulse‚ sometimes called total impulse‚ is the product of thrust and the effective firing duration. A shoulder fired rocket such as
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This law states that the orbital period of a planet is proportional to the cube of the semi-major axis of the ellipse. This law’s equation consists of calculating the planet’s orbital period and average distance. This law calculates the speed of a planet’s orbit. This law also describes that there is a T^2/R^3 for any satellite for any planet. The equation
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