Distant metastases are commonly observed in patients of osteosarcoma with the estimation of about 85% after surgery. Mostly they occur in lungs however it may also metastasizes to other bone and soft tissues. Osteosarcoma is lethal because of pulmonary metastasis with widespread progression that leads to respiratory failure. Tumor invasion and metastasis is multistep complex process in which tumor cells alter cell–extracellular matrix (ECM) interactions at the primary tumor site to invade adjacent
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BIO 30 4TH EXAM REVIEWER Merlyn S. Mendioro Delayed and Extra-chromosomal Inheritance 1.) Genetic factors that are located outside the chromosome: plasmagenes‚ plasmons‚ cytogens‚ plasmids. 2.) Plasmid inheritance implies: perpetuation through DNA Replication. 3.) Killer gene particulate material in Paramecium aurelia: kappa 4.) Mirabilis jalapa shows extrachromosomal inheritance in the ___________. When a pale male parent is crossed with a green female the result usually is
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disorder with many names. It is also known as Myositis Ossificans Progressive‚ Munchmeyer disease‚ or just casually Stone Mans Disease. The term Myositis Ossificans‚ is favored to the term Fibrodysplasia Ossificans Progressiva‚ because the ectopic osteogenesis occurs in the connective tissue within muscles‚ fasciae‚ tendons‚ ligaments‚ and joint capsules rather than in the muscle fibers themselves. It is a very rare autosomal dominant disorder that is characterized by swelling of the muscles‚ which
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Musculoskeletal Physiology Be familiar with bones and muscles of body 3 types of muscle skeletal‚ smooth‚ cardiac attaches muscle to bone‚ decreasing angle of joints during contraction proximal part of esophagus doesn’t connect to bone‚ proximal (upper) conscious control is primary skeletal‚ distal is involuntary and smooth muscle T- tubules: inside is ECS‚ deep invaginations of plasma membrane in muscle cell PM is sarcolemma allows high concentration of Ca‚ like other EC spaces (IC is
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micrognathia- small jaw! - progenia- premature ageing! - fordyce spots- raised sebaceous (sweat) glands! - dens in dente- tooth within tooth ( coronal more common)! - amelogenesis imperfecta- AR disorder of enamel—>small‚ discolored‚ pitted or grooved‚ and prone to rapid wear and breakage! - dentinogenesis imperfecta- dentin dysplasia that causes teeth to be discolored (most often a blue-gray or yellow-brown color) and translucent giving teeth an opalescent sheen! - aplasia- congenital absence
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Table 21-2 SUMMARY OF NEWBORN ASSESSMENT *MCH pages 479-473 | NORMAL | ABNORMAL (POSSIBLE CAUSES) | NURSING CONSIDERATIONS | Initial AssessmentAssess for obvious problems first. If infant is stable and has no problems that require immediate attention‚ continue with complete assessment. | Vital Signs | TemperatureAxillary: 36.5– 37.5°C (97.7 – 99.5°F).Axilla is preferred site. | Decreased (cold environment‚ hypoglycemia‚ infection‚ CNS problem). Increased (infection‚ environment to warm)
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Giuseppe Martello 1st year medical English of “Vasile Goldis” University Cranial Malformations Cranial defects are some of the most serious birth defects affecting children today‚ due to the potential for these birth defects to cause significant damage to the skull and brain. One of the most common types of cranial defects is a congenital malformation called craniosynostosis. In children born with craniosynostosis‚ the cranial sutures close earlier than normal‚ causing an abnormal growth
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BSC GROUP PROJECT Babies start developing their 300 bones during the second trimester‚ according to MayoClinic.com. As your baby grows in utero‚ her bones turn from cartilage to bone‚ then fuse together to form an adult like skeleton. The bones that make up your baby’s skeleton are alive‚ growing and changing‚ just like the rest of her body. The periosteum--a thin‚ dense membrane made of nerves and blood vessels that nourish the bone--comprises the outer surface of bone. Compact bone is the next
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removed‚ creating medullary cavity iii. through remodeling‚ spongy bone formed can be converted to compact bone. 5. lengthening of long bones - occurs at specialized regions: epiphyseal plates - contain epiphyseal cartilage that actively osteogenesis that increases the length of the region - occurs from birth will early 20s at puberty‚ the combination of rising levels of sex hormones‚ growth hormone and thyroid hormone stimulates bone growth
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“Highlights of the 2007 Progeria Research Foundation Scientific Workshop: Progress in Translational Science” Imagine having one of the rarest genetic diseases in the world: Progeria. Also known as Hutchinson-Gilford Progeria‚ this disease classifies only 50 patients worldwide. In 2007‚ the Children’s Hospital Boston aimed at enhancing the life for children with Progeria. The Progeria Research Foundation (PRF) and many other agencies aided the hospital with this goal of finding treatments
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