various human tissues‚ including intestinal epithelium‚ adrenal gland‚ placenta‚ kidney‚ liver‚ endothelial cells and testicular tissue‚ and P-gp naturally protects these organs against xenobiotics. P-gp substrates include adriamycin‚ daunorubicin‚ paclitaxel‚ vincristine‚ vinblastine‚ and imatinib. In cancer‚ P-gp was identified as a protein responsible for resistance to many
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CANCER RISK FACTORS: * Human papilloma virus infection * Smoking * Immunosuppression * Chlamydia infection * Diet * Oral contraceptives (birth control pills) * Intrauterine device use * Multiple full-term pregnancies * Young age at the first full-term pregnancy * Poverty * Diethylstilbestrol (DES) * Family history of cervical cancer PREVENTION Testing (screening) * Regular Pap test * Pelvic exam * Condoms and HPV * Don’t smoke
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Piperazine (generic‚ Vermizine) Oral: piperazine citrate tablets equivalent to 250 mg of the hexahydrate; piperazine citrate syrup equivalent to 500 mg of the hexahydrate per 5 mL Praziquantel (Biltricide; others outside the USA) Oral: 600 mg tablets (other strengths outside the USA) Pyrantel pamoate (Antiminth‚ Combantrin‚ Pin-rid‚ Pin-X) Oral: 50 mg (base)/mL suspension; 62.5 mg (base) capsules (available without prescription in the USA) Suramin (Bayer 205‚ others) Parenteral: ampules containing
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Functions and structure of plant terpenes Terpenes are an enormous class of organic compounds‚ that are produced by a wide variety of plants and fungi‚ especially conifers. Terpenes are also produced by some of the living organisms‚ like swallowtail butterflies. They emit terpenes from their osmeterium. Terpenes are important materials for a plant as components of its body and as a material to protect it from external enemies since it has a strong smell and colorless. Terpenes are found in biological
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What You Need to Know About Itching Itching can be one of the cruelest forms of torture known to man. In many ways‚ it is one of the most annoying side effects of cancer and many of the medications that are used to treat it. There are two forms of itching the average cancer patient may experience‚ itching that comes on suddenly is referred to as "acute"‚ and itching that occurs over a longer period of time is referred to as "chronic". The itching might occur by itself or along with various other
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Taxol is an anticancer drug produced by extraction from the bark of the pacific yew tree called Taxus brevifolia‚ which was discovered by Harvard trained botanist called Arthur Barclay in 1962 (wall and wani‚ 1995). It was renamed to paclitaxel when it was commercially developed. It is in a form of whitish crystalline powder with a melting point of 216 ºC‚ very insoluble in water‚ highly lipophilic‚ higher protein binding rate and disturbs the structure of the inner part of the cell membrane (Goldspiel
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Introduction to Biology Lab- Pre-lab for Ecology Lab #8 A.) Hierro‚ Jose L.‚ and Ragan M. Callaway. "Allelopathy and Exotic Plant Invasion." Plant and Soil 256.1 (2003): 29-39. Springer.com. Kluwer Academic Publishers‚ 13 May 2003. Web. 7 Mar. 2013. <http://download.springer.com/static/pdf/801/art%253A10.1023%252FA%253A1026208327014.pdf?auth66=1363980296_005e124552dacf48bf5fb9abb2861861&ext=.pdf>. B.) This article documented an experiment done on an invasive forb found in the
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*Since male breast cancer has different stages that a man can be diagnosed with that also means that there are different treatments for each diagnosis. The first step that a man would take is a biopsy‚ this usually a common procedure that a doctor will do to get the information they need to make a diagnosis. Along with the biopsy there are other surgeries that may be necessary.Chemotherapy is another treatment that is common for a man to do with breast cancer‚ but it may not be necessary for the
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Medicinal Plants Introduction Introduction “In All things there is a poison‚ and there is nothing without a poison. It depends on only upon the dose whether a poison is a poison or not”---------Paracelsus (1493?-1541‚ Switzerland) Chinese saying “Shi Yao San Fei Du” means “Any drugs have toxic effects”. Introduction: Why Study Medicinal Plants Medicinal plants and religions • Medicinal plants have played an essential role in the development of human culture‚ for example religions
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It is well known that Gliomas are amongst the most destructive types of cancers out there. Unfortunately‚ Gliomas are the most frequent tumors in the central nervous system accounting “for more than 32% of all primary brain and CNS tumors and 80% of all malignancies of the brain and CNS”. Tons of research has been done in this topic with a variety of different methods‚ however‚ it still has a poor prognosis with frequent recurrences. The gold standard so far to treat this type of tumors has been
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