Experiment 3: The preparation of acetaminophen (paracetamol) with thin layer chromatography (TLC) to monitor the reaction. Abstract: This experiment is to demonstrate the preparation of paracetamol and its properties. Reflux and filtration of 4-aminophenol and acetic anhydride formed the crude sample. Further analysis of dry white crystals were used to give quantitative measurements and a percentage yield of 46% was obtained. The overall conclusion is that the acetic anhydride reacted with the
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Evaluation of Paracetamol Content in Tablet Dosage Form Using UV-Spectrophotometry Casilagan‚ Camela Mae C.‚ and Jimenez‚ Joshua M. Chemistry Department‚ College of Science Adamson University Ermita‚ Manila 1.0 Introduction UV-Visible Spectrophotometry is a widely-used technique in Chemical and Pharmaceutical Analysis. And this method has been very useful both for Qualitative and Quantitative Applications‚ especially for organic compounds. Some of its advantages for Quantitative purposes
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Task 3: M1 I weighed my paracetamol tablets before I started the experiment so I was able to work out the percentage yield and percentage purity. If I never weighed the paracetamol tablets which I used‚ the calculations wouldn’t be accurate. I warmed the two paracetamol tablets with propanone in warm water in order to dissolve the paracetamol and soluble impurities. This then left the undissolved material which I was then allowed me to carry out filtration and remove any insoluble impurities. The
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QUALITY EVALUATION OF PARACETAMOL IN THE BULK‚ DOSAGE FORMS AND BODY FLUIDS USING THE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY (HPLC) TECHNIQUE S. Asare-Nkansah and J.K. Kwakye Department of Pharmaceutical Chemistry‚ Faculty of Pharmacy and Pharmaceutical Sciences‚ Kwame Nkrumah University of Science and Technology‚ Kumasi‚ Ghana ABSTRACT High Performance Liquid Chromatography has been used to evolve an analytical procedure for the evaluation of the content of paracetamol in the bulk‚ dosage
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It was concluded that the product created was paracetamol when a thin layer chromatography test was performed and observed under ultraviolet light (which is discussed further down the page). An unknown substance was treated with acetic anhydrate and resulted with paracetamol. A compound that behaves in this matter is 4-aminophenol and is widespread in the industrial production of this drug. Upon these observations was the build up of “Chemical A” decided. When 4-aminophenol is t treated with
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fake versions containing either the wrong ingredients or inaccuracy of the active ingredient which can cause toxicity issues in patients using these products. The aim of this experiment is to find if the percentage composition of the label (50% paracetamol‚ 40% aspirin and 10% sucrose) matches that of the percentage composition of the powder by following 10% ranges of each component in the powder. I am going to do this via a number of methods including vacuum filtration‚ heating‚ extraction and evaporation
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TRADE NAME | STRENGTH | NOS. | REMARKS ( CONTACT FOR QUERY/ DOUBTS | | ENT | | | | CONTACT DR J. SHROFF 09824299422 | 1 | TAB CEFADROXYL | DAX500 | 500mg | 840 | | 2 | TAB CEFADROXYL | DAX250 | 250mg | 400 | | 3 | TAB DICLOFENAC + PARACETAMOL | - | - | - | N/A(AVAILABLE SEPARATELY) | 4 | TAB DIOMINIC DA/SIMILAR DECONGESTENT | - | - | - | AVAILABLE SEPARATELY | 5 | CIPROFLOXACIN &DEXAMETHASONE EAR DROPS | - | - | 60 | | 6 | GENTAMYCIN EAR DROPS | - | - | 60 | | 7 | OTRIVIN
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to moderate pain such as headaches‚ migraines‚ or for lowering a high temperature or relieving aches or discomfort associated with colds and flu. Panadol contains around 500 grams of Paracetamol‚ which is a mild and safe pain reliever. Due to its composition of Paracetamol‚ the pain is relieved because the paracetamol reduces the production of prostaglandins in the brain and spinal cord. Prostaglandins are produced when injury or certain diseases affect the body‚ and so they give off warning to the
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whilst on my undergraduate internship. The call was for a nine month old baby boy who was suffering from pyrexia and had a history of febrile convulsions (1). Mum called an ambulance as she could not get his temperature down‚ she was giving him oral paracetamol but he had vomited after each dose that he had been given so he was not getting the required amount into his system and she was afraid that he would have another febrile convulsion. I’ll explain the call and the treatment we provided to the patient
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Chemicals SAMPLE NAME: Paracetamol Tablets ANALYSIS REQUIRED: Paracetamol CLAIM: Each tablet contains 500mg Paracetamol. THEORY: Paracetamol IUPAC Name: N-(4-hydroxyphenyl)ethanamide N-(4-hydroxyphenyl)acetamide Molecular Formula: C8H9NO2 Chemical Structure: Paracetamol INN or acetaminophen USAN is a widely used over-the-counter analgesic (pain reliever) and antipyretic (fever reducer). It is commonly used for the relief of headaches and other minor aches and pains and is a major ingredient in
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