SICKLE CELL ANEMIA Tina Thompson‚ Ashley Scott‚ Araceli Galindo‚ Roshanda Dixon‚ Kristen Wyatt‚ Kimberly Dennis What is Sickle Cell Anemia? Sickle cell anemia is a severe hemolytic anemia resulting in a sickle shaped hemoglobin molecule. It is an inherited disorder with some having sickle cell trait and some having sickle cell disease. The sickle hemoglobin gene is known as the HbS gene. It is found predominantly in people of African descent and occasionally in those of Mediterranean descent
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The benefits of hydroxyurea therapy in sickle cell anemia are extensive and well established‚ and were first demonstrated by the Multicenter Study of Hydroxyurea in Sickle Cell Anemia‚ a double blind‚ placebo controlled trial in 299 adults with sickle cell anemia. The clinical trial‚ which lasted for 21 months‚ showed that patients with sickle cell anemia treated with hydroxyurea had dramatically fewer painful episodes than those who received placebos. Firstly‚ among the 299 adults studied at 21
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Understanding the Functions of Proteins and DNA Ingrid Waldron‚ Biology Department‚ University of Pennsylvania‚ 2012 These key concepts and activities are suggested as part of an introductory unit on biological molecules (or as an introduction to a unit on molecular biology). The overarching goal is to help students understand that proteins and DNA are not just abstract concepts in biology textbooks but rather crucial components of our bodies that affect familiar functions and characteristics
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pregnancy are common happen to pregnant women because woman body need a lot of nutrient to develop the growth of the fetus and also for pregnant women herself [3]. There are 3 types of anemic during pregnancy such as‚ iron-deficiency anemia‚ folate deficiency anemia and Vitamin B12 deficiency [3]. Some of the
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become a common tactic of organisations to reduce labour and operation costs. There is no denying that reducing a workforce could improve efficiency and contains several benefits; however‚ it also has a number of drawbacks and even brings long-term pernicious effects to organisations. In the following paragraphs‚ three major points will be discussed‚ including the selection process to decide who lay off‚ the possible negative effects‚ and the strategies to minimize the negative outcomes using theories
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monophosphates. Defects of vitamins B12‚ folate‚ and other genetic factors‚ can have an effect on bone marrow‚ production of an unbalanced relation between nuclear and cytoplasmic development and a postponed maturation of RBC’s‚ which leads to megaloblastic anemia. Vitamin B12‚ also known as cobalamin‚ is found in animal products and is made by specific microorganisms and not by plants. Antibodies may be present in the stomach acids which can either prevent the binding of vitamin B12 to intrinsic factor‚ or
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Study: Spherocytosis Spherocytosis is a condition that affects red blood cells. People with this condition typically experience a shortage of red blood cells which is anemia‚ yellowing of the eyes and skin also known as jaundice‚ and an enlarged spleen which is called splenomegaly. Most newborns with spherocytosis have severe anemia‚ although it improves after the first year of life. Splenomegaly can occur anytime from early childhood to adulthood. About half of affected individuals develop hard deposits
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them to travel through the small blood vessels and deliver oxygen to all of the body. Sickle cell disease(SCD) causes these red blood cells to form into a crescent shape‚ like a sickle. The sickle-shaped red blood cells easily break apart‚ causing anemia. Sickled red blood cells only live 10-20 days instead of the normal 120 days. The damaged sickle cells then clump together and stick to the walls of blood vessels‚ causing a blockage of blood flow. This can cause severe pain and permanent damage to
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damage and a low blood count--Sickle Cell Anemia. The overall incidence of SCD is eight out of 100‚000 people. However‚ it is much more widespread in some people. "One out of 600 African Americans and one out of 1‚000 to 1‚ 400 Hispanic Americans" are affected. (2). However‚ there are other populations who are especially affected‚ as well. These include‚ but are not limited to "Arabs‚ Greeks‚ Italians‚ and people
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I. Identify and Guess (10 points) Hmmmm….what do you think these underlined words in the following sentences mean? Write your educated guess in the space provided beneath each context clue. 1. One of the reasons I don’t like to use medicines like cough syrup is that the taste is absolutely vile; if I’m supposed to be able to tolerate it‚ you’d think that the makers would make it less disgusting. 2. Mrs. Hatcher announced that in all her years of teaching second
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