single-dose‚ randomized‚ 2-way crossover design under fasting conditions. Statistical analysis of the pharmacokinetic parameters Cmax‚ AUC0-72‚ and AUC0-∞ was conducted to determine bioequivalence (after log-transformation of data using analysis of variance and 90% CIs) and to gain marketing approval in Egypt. The formulations were considered to be bioequivalent if the log-transformed ratios of the 3 pharmacokinetic parameters were within the predetermined bioequivalence range (ie‚ 80%–125%)‚ as established
Premium Statistics Statistical significance Pharmacology
. What type of medication is prescribed to diabetics? Insulin. 2. What type of medication is prescribed to diabetics? For human insulin‚ it is consists of two polypeptide chains in which the chain A has 21 amino acids and chain B has 30 amino acids (Beta Cell Biology Consortium‚ 2014). Other than that‚ the two polypeptide chains are connected by two inter-chain disulfide bridges (Beta Cell Biology Consortium‚ 2014). For insulin from other animals‚ the structure is almost the same as human insulin
Premium Diabetes mellitus Blood sugar Insulin
ASSIGNMENT ON PHARMACEUTICAL IMPORTANCE OF STEREOCHEMISTRY PREPARED FOR: Nowshin Nowaz Rumzhum Lecturer‚ Dept. of pharmacy Stamford University Bangladesh PREPARED BY: Md. Wahid Rezwan ID No: BPH02805674 Batch No: 28th D STAMFORD UNIVERSITY BANGLADESH Introduction: Stereochemistry may seem like a trivial
Premium
pump. • stimulate an exchange mechanism • They increases level of CALCIUM inside the cell • More calcium will accumulate inside the cell during cellular depolarization • Positive inotropic effect • Negative chronotropic effect Clinical pharmacokinetics • Digitalization – produce an effective blood level • Maintenance – maintain therapeutic level • Digoxin and digitoxin • Both can administered orally and IV. The t 1/2 life of digoxin is normally 1.5 to 2.0 days. The t1/2 life of digitoxin is
Premium Hypertension Myocardial infarction
|Pharmacy | |Sr. No. |Core Areas |Percentage | |1. |Pharmaceutics |20% | |2. |Pharmaceutical Chemistry
Free Pharmacology
Renal disease case study This case relates to renal disease; therefore~ purposefully look into the medication use and vocabulary as they relate to renal patients. Vocabulary: Before attempting to work the case study‚ define each of the vocabulary words. Although the words may have several subheadings‚ it will give you a place to begin your inquiry. When reviewing the vocabulary words‚ you might want to ask several questions: who‚ what‚ where‚ when‚ why and how. This should give you a much broader
Premium Hypertension Chronic kidney disease Kidney
conditions need different routes of administration. A specific dosage form may be a requirement for certain kinds of drugs because of issues with various factors like chemical stability or pharmacokinetics. The route of administration is a path in which a drug or other substance enters the body. The pharmacokinetic properties‚ such as absorption‚ distribution‚ metabolism‚ and excretion‚ of a drug are critically influenced by the route of administration. The United States Food and Drug Administration
Premium Pharmacology Route of administration Dosage form
Curcumin is found in the rhizome of Curcuma longa. It exhibits various biological activities like anti-cancer‚ anti-inflammatory‚ anti-viral‚ anti-bacterial‚ anti-oxidant and nematocidal activities. Due to its poor solubility there is a need to formulate this curcumin for better bioavailability. Curcumin was extracted by acetone using soxhlet apparatus and evaporated by means of vacuum rotary evaporator. The presence of curcumin was confirmed by differential scanning calorimetry. Nanosuspension was
Premium Bacteria Antibiotic resistance Microbiology
Overview of Antifungal Agents George R.Thompson III‚ MD‚ FACPa‚b‚*‚ Jose Cadena‚ MDa‚b‚ Thomas F. Patterson‚ MDa‚b KEYWORDS Fungal infection Invasive mycoses Triazoles Echinocandins Amphotericin Flucytosine The number of agents available to treat fungal infections has increased by 30% since the year 2000‚ yet still only 15 agents are currently approved for clinical use. The greater number of medications now available allows for therapeutic choices; however‚ differences in antifungal
Premium Candidiasis Antifungal drug
CathyAnne‚ great post about Grandma’s medications. Great catch on the hydrochlorothiazide. As this patients’ new provider‚ I would find it important to educate the patient on her medical conditions and the medications that she is taking. If patient gives consent to having daughter in the room for this I would try to include the daughter so that someone would possibly be able to assist patient with her medication regimen. Important topics in the education that I would want to be talking about are
Premium Health care Patient Health care provider