°Thioridazine hydrochloride‚USP. Is a member of the piperizine subgroup of the phenothiazines. Thioridazine occurs as a white or slightly yellow‚ crystalline or micronized powder‚ which is odourless or has a faint odor and is practically insoluble in water and freely soluble in dehydrated alcohol. The drug has sedative and hypotensive activity in common with chlorpromazine and less antiemetic activity. thioridazine is indicated for the treatment of schizophrenic patients who fail to respond
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Drug Journey Thesis: The process of drugs in pharmaceuticals is actually a very long one. There are several different stages that a company undertakes in order to get their drug to the doctors‚ pharmacists and patients. We will look at this process over the next few minutes. Introduction: As a Chemistry major I’m passionate to study on drugs and would like to involve in pharmaceuticals. I’m also inspired from my family where my brothers-in-law are pharmacist and besides I love chemistry since
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References: Abdel Bar‚ F.M.‚ Khanfar‚ M.A.‚ Elnagar‚ A.Y.‚ Badria‚ F.A.‚ Zaghloul‚ A.M.‚ Ahmad‚ K.F.‚ . . . ‚ El Sayed‚ K.A. (2010). Design and pharmacophore modeling of biaryl methyl eugenol analogs as breast cancer invasion inhibitors. Bioorganic & Medicinal Chemistry‚ 18‚ 496–507. Aboutabl‚ E.A.‚ El Tohamy‚ S.F.‚ De Footer‚ H.L.‚ & De Buyck‚ L.F. (1991). A comparative study of the essential oils
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breaks down food or when you are exposed to tobacco smoke or radiation .The build up of free radicals over time is largely responsible for the aging process. Free radicals may play a role in cancer‚ heart disease‚ and conditions like arthritis. The pharmacophore of vitamin C is ascorbate ion which is an anti-oxidant that protect the body against oxidative stress. Ascorbate acts as a reducing .When there are more free radicals compared to an anti-oxidant in the body‚ a human is under the condition called
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International Journal of Pharmaceutics 201 (2000) 131 – 150 www.elsevier.com/locate/ijpharm Review Biopharmaceutics and pharmacokinetics in drug research Ramesh Panchagnula *‚ Narisetty Sunil Thomas Department of Pharmaceutics‚ National Institute of Pharmaceutical Education and Research‚ Sector 67‚ S.A.S. Nagar‚ Punjab 160 062‚ India Received 7 September 1999; received in revised form 6 January 2000; accepted 6 January 2000 Abstract With the synergistic and multiplicative interactions
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EVALUATION OF ANTI-INFLAMMATORY EXTRACT EFFECT OF Argemone mexicana ON ALBINO RATS INTRODUCTION 1.1 Inflammation: Inflammation could be defined as the complex biological response of vascular tissue to harmful stimuli such as pathogen‚ damaged cells or irritants. It is a protective attempt by the organism to remove injurious stimuli as well as initiate the healing process for the tissue. This is achieved by diluting‚ destroying or otherwise neutralizing harmful agents (e.g. microbes or toxins)
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A General Review of Tetracyclines Antibiotics Chang Liu Instructor: Prof. Jasson Sello Department of Chemistry‚ Brown University Providence 02906‚ RI Tetracyclines are the first broad-spectrum antibiotic to be applied to clinic use. Nevertheless‚ the increasing incidence of bacterial resistance of tetracyclines led to a series of studies on the development of semisynthetic tetracyclines to circumvent the resistant organisms. In order to better design the structures of tetracycline derivatives
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Marine organisms and other novel natural sources of new cancer drugs Gilberto Schwartsmann South-American Office for Anticancer Drug Development (SOAD)‚ Comprehensive Cancer Centre (CINCAN)‚ The Lutheran University (ULBRA) & Postgraduate Course in Medicine (UFRGS)‚ Porto Alegre‚ Brazil Introduction Man has always relied on nature for survival. Since ancient times‚ nature has been our main source of food‚ protection‚ clothing‚ transportation and remedies [1‚2]. This can be illustrated by the
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IDEA FINDER: http://www.ideafinder.com/history/inventions/aspirin.htm Acetaminophen Acetaminophen. (2008‚ April 27). Retrieved April 20‚ 2012‚ from NEW WORLD ENCYCLOPEDIA: http://www.newworldencyclopedia.org/entry/Acetaminophen What is the pharmacophore of paracetamol acetaminophen‚ aspirin‚ and caffeine. (2011‚ August 23). Retrieved March 30‚ 2012‚ from Drugs.com: http://www.ehow.com/about_4564995_acetaminophen-vs-aspirin.html Paracetamol Tablets What is the drug Paracetamol? (2011). Retrieved
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5 Computational Virtual Screening Towards Designing Novel Anticancer Drugs Po-Yuan Chen1‚2 1Department of Biological Science and Technology‚ China Medical University‚ Taichung‚ Taiwan‚ 2Brain Research Centre‚ University of British Columbia‚ Vancouver‚ 1Republic of China 2Canada 1. Introduction Generally speaking‚ Docking is most popular and critical issue in this research field‚ because it contains most important information both Ligands (Drugs) and Receptors (it can be intracellular protein
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