Kuroda et al. Skeletal Muscle 2013‚ 3:5 http://www.skeletalmusclejournal.com/content/3/1/5 Skeletal Muscle Open Access RESEARCH Canonical Wnt signaling induces BMP-4 to specify slow myofibrogenesis of fetal myoblasts Kazuki Kuroda1‚4‚ Shihuan Kuang1‚2‚ Makoto M Taketo3 and Michael A Rudnicki1* Abstract Background: The Wnts are secreted proteins that play important roles in skeletal myogenesis‚ muscle fiber type diversification‚ neuromuscular junction formation and muscle stem cell function
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Exercise 8 Simple Muscle Contraction • 3 Phases AB - lag phase or latent phase - (shortest) 0.00sec‚ usually less than 0.01sec - brief period that exists between the application of the stimulus and the start of contraction BC - contraction‚ 0.05sec - peak - shortening of the muscle occur CD - relaxation period‚ 0.05 sec - Occurs when Ca+ is transported back in the sarcoplasmic reticulum Single muscle contraction= 100vib/sec (tuning fork)= 0.10 sec 10vib (result) Neuromuscular junction - formed when
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Biochemistry of Muscle Contraction Fred P. Guillergan M.D.‚ FPCP Outline histology and biochemistry of muscles (Striated & smooth) – Myosin – Actin‚ Tropomyosin‚ Troponin – Accessory proteins of muscles Biochemical events in muscle contraction Calcium‚ Ca2+-binding proteins and Ca2+ channels in muscle contraction Biochemistry of Cardiac & Smooth muscle contraction Energetics of muscle contraction ☻Able to understand the normal anatomy and physiology of different types of muscles ☻ Provide
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Determining the Latent Period 1. Click Clear Tracings to erase the oscilloscope display. The voltage should be set to 5.0 volts. 2. Drag the 200 msec button to the right edge of the oscilloscope. 3. Click the Stimulate button once‚ and allow the tracing to complete. 4. When you measure the length of the latent period from a printed graph‚ you measure the time between the application of the stimulus and the beginning of the first observable response(increase in force). The computer can’t “look ahead
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Muscle Contraction Helpful links: Diagrams: http://themedicalbiochemistrypage.org/muscle.php http://classes.midlandstech.edu/carterp/Courses/bio210/chap09/lecture1.html Good explanations: http://science.howstuffworks.com/life/human-biology/muscle2.htm Quiz: http://www2.muw.edu/~jfortman/220practst2.html Flashcards: http://quizlet.com/17858377/physiology-ch-8-muscles-flash-cards/ http://quizlet.com/16553525/quiz-4-flash-cards/ http://quizlet
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The Aging Musculoskeletal System The human musculoskeletal system is the organ system that gives humans the ability to physically move‚ by using the muscles and skeletal system. It consists of the muscular system and the human skeleton. Bones are connected to each other at the joints by ligaments or cartilage and skeletal muscle is attached to bones‚ usually by tendons. Bones mass or density is lost as people age‚ especially in women after menopause. The bone loses calcium and other minerals. Bone
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Muscle contractions tend to be smooth and vary in strengths‚ depending on the demands placed on them. The variations of strength are called graded muscle responses. There are two ways a muscle contraction can be graded‚ either by changing the frequency of stimulation or by changing the strength of the stimulation. When a muscle is responding to a change in stimulus frequency‚ the nervous system will reach a greater muscular force when increasing the firing of motor neurons. This causes a wave or
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When it comes to muscle contraction‚ contraction takes place in the muscle fibers. Muscle fibers are the basic building blocks of the muscle and what allow muscles to contract. They appear as long cylinder cells that contain several nuclei. Contraction happens when the muscle receive signals from the nervous system and the Neuromuscular Junction obtains the muscular exchange where the synaptic bulb and the muscle fibers connect. muscle fibers are composed of myofibrils‚ which contain contractile
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Nutrition A Muscle Contraction Muscle Contraction is part of an organ in the body that is tensive. It may have a process of tensions that may be developed with muscle tissues. Contraction can be a meaning of shortening or long. Muscle Contraction can also produce a muscle cell that is for movement of the body. Myosin and Actin is an interaction protein to Muscle Contraction‚ it can be changed by shape but not by volume. Skeletal Muscle contraction is produce by heat. The muscles may receive signal
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hysioEx 9.0 – Exercise 2: Skeletal Muscle Physiology Name: Chart 1: Latent Period Results Voltage Active force (g) Latent period (msec) 0.0 0.00 XXXXXXXXXX 3.0 1.04 XXXXXXXXXX 4.0 1.32 2.40 6.0 1.65 2.40 8.0 1.81 2.40 10.0 1.81 2.40 Chart 2: Effect of Stimulus Voltage on Skeletal Muscle Contraction Voltage Active force (g) 0.0 0.00 0.2 0.00 0.8 0.02 1.0 .15 1.5 .43 2.0 .66 2.5 .87 3.0 1.64 3.5 1.19 4.0 1.32 4.5 1.42 5.0 1.51 5.5 1.59 6.0 1.65 6.5 1.70 7.0 1.74 7
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