Exercise 6: Cardiovascular Physiology Worksheet Assignment Due: Week 6 Electrical Stimulation Activity 1: Direct Heart Stimulation 1. Did you see any change in the trace? I did not see a change in the trace 2. Why or why not? This is because it needs more stimulation 3. Did you see any change in the trace? I did see a change in the trace 4. Why or why not? This is because there is double stimulation. 5. Describe the change you see in the trace. How does it differ from the baseline
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Exercise 1: Cell Transport Mechanisms and Permeability Worksheet Student Name: Student ID# Student instructions: Follow the step-by-step instructions for this exercise found in your lab manual and record your answers in the spaces below. Submit this completed document by the assignment due date found in the Syllabus. Rename this document to include your first and last name prior to submitting‚ e.g. Exercise1_JohnSmith.doc. Please make sure that your answers are typed in RED. Grading:
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Activity 1 Pre-Lab Quiz K+ inside a cell = 150 mM; K+ outside a cell = 5 mM Na+ inside a cell = 5 mM; Na+ outside a cell = 150 mM Stop & Think question What is the polarity of the resting membrane potential (voltage)? Negative What does it mean that the voltage just inside the membrane is negative? B Membrane of most cells contains K+ leak channels…..b What will happen to the resting membrane potential if the extracellular K+ concentration is increase? Less negative What happens
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Activity 1 1. Increasing extracellular K+ reduces the net diffusion of K+ out of the neuron through the K+ leak channels because the membrane is permeable to K+ ions. Therefore‚ the K+ ions will diffuse down its concentration gradient from a region of higher concentration to a region of lower concentration. 2. Increasing extracellular K+ causes the membrane potential to change to a less negative value because the K+ ions diffuse out across the membrane. My results went well compared to my prediction
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Exercise 2: Skeletal Muscle Physiology: Activity 2: The Effect of Stimulus Voltage on Skeletal Muscle Contraction Lab Report Pre-lab Quiz 1. Skeletal muscle fibers are innervated (stimulated) by c. motor neurons. 2. A single action potential propagating down a motor axon results in d. a single action potential and a single contractile event in the muscle fibers it innervates. 3. In resting skeletal muscle‚ calcium is stored in c. the sarcoplasmic reticulum. 4. During the latent period
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Electrical Stimulation Activity 1: Direct Heart Stimulation 1. Did you see any change in the trace? No change in the trace 2. Why or why not? This is because it needs more simulation 3. Did you see any change in the trace? I did see a change in the trace 4. Why or why not? There is double stimulation 5. Describe the change you see in the trace. How does it differ from the baseline trace? The trace increased from the baseline trace 6. What effect do the repeated stimuli
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PhysioEX notes Autorhythmicity- heart’s ability to trigger its own contractions Phase O- a lot like depolarization in neuronal action potentials. Sodium channels open‚ increase of sodium INTO cell. Phase 1- sodium channels close‚ potassium channels close‚ decrease in potassium and sodium. Calcium channels open‚ increase of calcium into cell. Phase 2- Plateau phase‚ membrane still depolarized (contract). Potassium channels closed‚ L-type calcium channels stay open. Lasts 0.2 seconds/200
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Activity 1: Electrical Stimulation 1. Do you see any kind of response on the oscilloscope screen? NO 2. What was the threshold voltage‚ or the voltage at which you first saw an action potential? 3.0 V 3. How does this tracing compare to the one that was generated at the threshold voltage? The tracing travel in the same fashion but the tracing were different with an increase threshold voltage 4. What reason can you give for the change? Increase voltage 5. Record this maximal voltage here:
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PHYSIO EX 1 Simulating Dialysis (Simple Diffusion) 1. Describe two variables that affect the rate of diffusion. The temperature of the solutions and the difference in concentration of the ion or molecule between the sides of the membrane 2. Why do you think the urea was not able to diffuse through the 20 MWCO membrane? How well did the results compare with your prediction? Since the chemical formula for urea is (NH2)2CO and its molecular weight is about 60. It will not diffuse through the
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Assignment 1. 1. Summarise the main development of a child from the age range 0-2 years‚ 3-5 years and 5-8 years. 0-2 Years Newborn babies grow extremely quickly. During ‘Infancy’‚ which lasts from birth to eighteen months‚ babies change from a helpless newborn‚ to a child who can lift up their own head at three months‚ sit up unsupported at six months‚ walk at sixteen months and kick and throw a ball at two years old. Newborn babies actually lose some of their birth weight to begin with
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