Exercise 6: Cardiovascular Physiology Worksheet Assignment Due: Week 6 Electrical Stimulation Activity 1: Direct Heart Stimulation 1. Did you see any change in the trace? I did not see a change in the trace 2. Why or why not? This is because it needs more stimulation 3. Did you see any change in the trace? I did see a change in the trace 4. Why or why not? This is because there is double stimulation. 5. Describe the change you see in the trace. How does it differ from the baseline
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Exercise 1: Cell Transport Mechanisms and Permeability Worksheet Student Name: Student ID# Student instructions: Follow the step-by-step instructions for this exercise found in your lab manual and record your answers in the spaces below. Submit this completed document by the assignment due date found in the Syllabus. Rename this document to include your first and last name prior to submitting‚ e.g. Exercise1_JohnSmith.doc. Please make sure that your answers are typed in RED. Grading:
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Activity 1 Pre-Lab Quiz K+ inside a cell = 150 mM; K+ outside a cell = 5 mM Na+ inside a cell = 5 mM; Na+ outside a cell = 150 mM Stop & Think question What is the polarity of the resting membrane potential (voltage)? Negative What does it mean that the voltage just inside the membrane is negative? B Membrane of most cells contains K+ leak channels…..b What will happen to the resting membrane potential if the extracellular K+ concentration is increase? Less negative What happens
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PHYSIO EX 1 Simulating Dialysis (Simple Diffusion) 1. Describe two variables that affect the rate of diffusion. The temperature of the solutions and the difference in concentration of the ion or molecule between the sides of the membrane 2. Why do you think the urea was not able to diffuse through the 20 MWCO membrane? How well did the results compare with your prediction? Since the chemical formula for urea is (NH2)2CO and its molecular weight is about 60. It will not diffuse through the
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line then jumped back to normal and then flat lined again it continue to follow this trace continuously. 7. What part of the trace shows the refractory period? The atrial contraction is the part of the trace that shows the refractory period 8. Does summation occur? No summation 9. Why is it important that summation not occur in heart muscle? Summation would increase the Heart muscle contractions which would lead to heart attack. Activity 2: Vagus Nerve Stimulation 1. Describe
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Activity 1: Electrical Stimulation 1. Do you see any kind of response on the oscilloscope screen? NO 2. What was the threshold voltage‚ or the voltage at which you first saw an action potential? 3.0 V 3. How does this tracing compare to the one that was generated at the threshold voltage? The tracing travel in the same fashion but the tracing were different with an increase threshold voltage 4. What reason can you give for the change? Increase voltage 5. Record this maximal voltage here:
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PhysioEX notes Autorhythmicity- heart’s ability to trigger its own contractions Phase O- a lot like depolarization in neuronal action potentials. Sodium channels open‚ increase of sodium INTO cell. Phase 1- sodium channels close‚ potassium channels close‚ decrease in potassium and sodium. Calcium channels open‚ increase of calcium into cell. Phase 2- Plateau phase‚ membrane still depolarized (contract). Potassium channels closed‚ L-type calcium channels stay open. Lasts 0.2 seconds/200
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Activity 1 1. Increasing extracellular K+ reduces the net diffusion of K+ out of the neuron through the K+ leak channels because the membrane is permeable to K+ ions. Therefore‚ the K+ ions will diffuse down its concentration gradient from a region of higher concentration to a region of lower concentration. 2. Increasing extracellular K+ causes the membrane potential to change to a less negative value because the K+ ions diffuse out across the membrane. My results went well compared to my prediction
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Jason A. Kautz University of Nebraska-Lincoln Matthew Lukeman Acadia University Copyright © 2014 Pearson Canada Inc. Slide 10-1 Q1: PCl3 is an industrial chemical used in many herbicides and insecticides. What is the molecular shape of PCl3? 1A) bent 2B) tetrahedral 3C) trigonal pyramidal 4D) T-shaped 5E) trigonal planar Copyright © 2014 Pearson Canada Inc. Slide 10-2 Q2: What is the approximate angle of the O─C─O bond in the citric acid molecule below? O O OH OH HO 1A) 120° 2B) 109.5°
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REVIEW SHEET EXERCISE 11 Blood Analysis NAME: LAB TIME/DATE: Hematocrit Determination 1. Hematocrit values are usually ( *higher / lower ) in healthy males‚ compared to healthy females. Give one possible explanation for this. 2. Living at high elevations will cause a person’s hematocrit to ( *increase / decrease ). Explain your answer. 3. Long-term athletic training will cause a person’s hematocrit to ( *increase / decrease ). 4. What is anemia? Condition where inadequate
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