Drug Metabolism Prof. Patrick Davis Basic Medicinal Chemical Principles PHR 143M Fall-08 Importance of Drug Metabolism • The basic premise: Lipophilic Drugs --> Hydrophilic Metabolites (Not Excreted) (Excreted) • Water soluble => increased renal excretion -anddecreased tubular re-absorption of lipophilics. Importance of Drug Metabolism CH 3 CH 2OH CHO COOH OH O C 2H 5 Δ1-THC PC=6000 - O C O O HO OH COO OH OH Excreted Form O C 2H 5
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5/ Predicate – the 2nd principal part of the sentence which expresses an action‚ state or quallity of a person or thing‚ expressed by the subject. The adverbal clause The adv cl erform the function of the adv mod It can modifie a V an adj or an adv in principle clause There are several types of adv cl: of time‚ place‚cause/reason‚ perpose‚condition‚consecion‚result‚manner comparison They are usualy joined with the pr cl by means of sub-g conj There is no usualy asyndetical coordination
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not able to achieve their goals‚ provide for our families‚ or attain the basic necessities needed to survive. Individuals also spend much more time in the work environment than they do at home or in any other place (U.S. Bureau of Labor Statistics‚ 2010) Organizational psychologists study the behaviors of people at work and the organization as a whole. The goal is to increase workplace productivity by focusing on the mental and physical well being of the employees. It is critical to study organizations
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Chapter 3: Defining and Measuring Crime The Uniform Crime Report (ucr) is an annually (yearly) report compiled by the FBI to give an indication of criminal activity. They organize offenses known to the police. The UCR divides the criminal offenses into categories: part 1 offense and part II offense. Part 1 offenses are crimes that are recorded by the FBI to give a general idea of the crime picture. Part 1 offenses crimes can be covered by the media and consequently inspire the most fear if crime
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Title : Investigation of Action of Saliva and 3M Hydrochloric Acid in Two Carbohydrate Solutions Objective : To investigate the action of saliva and 3M hydrochloric acid in two carbohydrate solutions Results : Table 1: Observations Conclusions Solution A Benedict’s test : Initial blue solution changed to brick-red precipitate. Little amount of brick-red precipitate suspended in solution. The solution was translucent. Iodine test : Yellowish-brown remained the same. Abundant amount of
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Abstract: Personal information is an essential part of our identification and is useful in many aspects of our life. However‚ it’s also becoming more and more vulnerable in contemporary society with a multitude of approaches for collecting and using people’s information emerges. The leak and abuse of personal information can cause serious troubles to people’s life and selling others’ information for commercial purposes has long been regarded as unethical behaviour in business world. With the backdrop
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important to this process‚ the older a person becomes the more medical services is needed. Since aging is a process that begins when you are conceived and continues for as long as we live out life span‚ our body reflects genetic components and environmental experience. So in a genetic way our bodies has the capacity to adapt and repair as well as collect damages from disease process. In this society‚ we now think of 65 to 74 years old as “young old”‚ 75 to 84 as “middle old” and 84 plus‚ as “ old old”
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organic matter. (1) II. Predators: Larger carnivores eat planarians. Some fish such as the Crossocheilus siamensis (Siamese Algae Eater) have been studied to remove planarians from fish tanks. (3) III. Range: Most planarians live in fresh-water bodies. They also live in all oceans‚ and in moist terrestrial habitats. (5) IV. Microhabitat: Planarians are light-sensitive and during the day will be found under logs‚ rocks‚ or dead leaves. They can be found in springs‚ ditches‚ marshes‚ ponds‚ and
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Measuring Earth with a Stick Have you ever heard of the Greek mathematician and astronomer Eratosthenes? His name is probably best known among astronomers. Why do they think so highly of him? Eratosthenes was born about 276 B.C.E. and received some of his education in Athens‚ Greece. He spent a good part of his life‚ however‚ in Alexandria‚ Egypt‚ which at that time was under Greek rule. In about 200 B.C.E.‚ Eratosthenes set out to determine the dimensions of the earth by using a simple stick
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TOPIC_1_2011: MEASURING A NATION’S INCOME PART 1: MULTIPLE CHOICES: 1. Macroeconomists study a. decisions of households and firms. b. the interaction of households and firms. c. economy-wide phenomena. d. regulations on firms and unions. 2. Which of the following questions is more likely to be studied by a microeconomist than a macroeconomist? a. Why do prices in general rise by more in some countries than in others? b. Why do wages differ across industries? c. Why
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