Mitochondria are a key organelle responsible for aerobic respiration in eukaryotic cells. The majority of the energy that eukaryotes rely on is obtained through the use of mitochondria‚ thus emphasizing the importance of these dynamic organelles. Due to the importance in respiration mitochondria are found in high abundance in oxidative tissues such as heart‚ kidney‚ and the brain1‚2 3. Inner mitochondrial membrane plays host to a collection of enzyme complexes termed the electron transport chain
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(VMAT). This transporter normally transports dopamine (DA)‚ 5-HT (serotonin)‚ and norepinephrine (NE) from the cytoplasm to the vesicle in the presynaptic neuron. Because these neurotransmitters are not packaged‚ they are degraded quickly by monoamine oxidases (MAOs). 4. Inhibition of synthesis of the neurotransmitter. Drug: p-chlorophenylalanine (PCPA) Pharmacology: Indirect serotonin antagonist. Primarily used in research. Mode of action: PCPA
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meningitidis a portion of the CSF and blood are drawn and grown on a chocolate agar plate or a Thayer-Martin medium‚ more selective because it includes antibiotics. Once a colony of bacteria is grown it is tested for oxidase‚ glucose‚ sucrose and carbohydrates maltose which are all positive signs of N. meningitidis. Polymerase chain reaction (PCR) tests are also available in most industrialized countries. It is quicker to determine the organism present even after a patient
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Co-MAO and gradual decrease in dosages‚ there should be a reduction of the number nicotinic receptors to normal levels. The selective MAOB inhibitor‚ helps offset the absence of other substances in tobacco that had previously inhibited monoamine oxidase activity to catabolize dopamine‚ norepinephrine‚ and serotonin
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Many anti-depressants available‚ specifically those containing monoamine-oxidase inhibitors‚ will actually suppress REM sleep. If the purpose of sleep truly is to consolidate information during REM then the use of these anti-depressants should theoretically result in memory impairment but that is not the case. Despite the ’Consolidation
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BENEFITS OF GREEN TEA Green tea is one of the types of tea that is entirely made out of leaves. It is also very popular in ancient times and it was originated in Asia’s country‚ China. Nowadays‚ more and more people enjoy the tea across the world. According to recent research‚ people not only drinking green tea but they find it into many things like toiletries‚ ice-cream‚ food and many more. Why are there many people looking for it ?. This is because green tea has many benefits which make it a
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greater calories they upload for your weight-reduction plan. as a substitute for buying these liquids‚ hold a glass of unsweetened home-brewed tea for your fridge. As a delivered bonus‚ home-brewed inexperienced or black tea incorporates greater polyphenols than bottled teas‚ in step with a record from FoxNews.com. upload taste with lemon or mint sprigs. What Counts as Water? live Hydrated and wholesome Water does not get the identical media interest as inexperienced tea‚ antioxidants‚ and the brand
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Antioxidants Antioxidants are natural compounds that are present in some foods‚ which help stabilize free radicals (a harmful unstable molecule produced naturally in the body as a bi-product of oxidation) and prevent them from damaging other cells. Importance of antioxidants Free radicals that are formed in the body are highly dangerous‚ as they are unstable molecules with an odd number of electrons. Since they have an odd number of electrons they seek and steal electrons from
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According to Rodak’s (2016)‚ Platelets‚ which are also known as thrombocytes‚ initiate the vessel wall repair when damaged to keep the integrity of blood vessel and regulate the hemostasis. Platelets are round or oval‚ no nucleus‚ and small in size ‚ ranging from 2 to 4 μm in dimater. They are vital to life and are studied for their significance physiology. Consequent to vessel injury‚ platelets are activated to form plug at the site of injury to prevent blood loss. Vessel injury exposes the subendothelial
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using S-adenosylmethionine as a methyl donor. Parkinson’s disease is caused due to the production of insufficient dopamine synthesis in brain….. Degradation of catecholamines The catecholamine is inactivated by oxidative deamination by monoamine Oxidase (MAO) and by o-methylation carried out by catechol-o-methyl-transferase (COMT) as the one-carbon donor. -Two reactions can occur in either direction -the aldehyde products of the MAO reaction are oxidized to the corresponding acids MAO: Inactivates
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