Progeria (Greek pro‚ "to‚ for" and geron‚ "old") is a genetic disease of childhood extremely rare‚ characterized by an abrupt and premature aging in children between their first and second year of life. It is estimated to affect one in 8 million live births. Not shown preference for any particular gender‚ but many more have been reported white patients (97% of affected patients). Progeria can affect different organs and tissues: bone‚ muscle‚ skin‚ subcutaneous tissue and vessels. The most severe
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Hutchinson-Gilford Progeria Syndrome Abstract Hutchinson - Gilford syndrome‚ or Progeria‚ is an extremely rare genetic disorder when children age at a tremendous pace. Although children born with Porgeria tend to look healthy‚ they begin to display many characteristics of fast-tracked aging around 18-24 months. These children develop growth failure‚ a loss of body fat and hair‚ aged-looking skins‚ stiffness of joints‚ cardiovascular disease and strokes. Children with Progeria die of atherosclerosis
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Hutchinson–Gilford progeria syndrome is an extreme rare genetic disorder that catastrophically influences children in pre-mature aging and dying in their teenagers. So far‚ all drugs used to treat this disease are focusing on reducing complications and extending the life spans of patients‚ but no treatment has been proven to treat this disease directly and effectively. Fortunately‚ the new drug named farnesyltransferase inhibitors appears recently in the research field of Hutchinson–Gilford progeria. My hypothesis
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“Highlights of the 2007 Progeria Research Foundation Scientific Workshop: Progress in Translational Science” Imagine having one of the rarest genetic diseases in the world: Progeria. Also known as Hutchinson-Gilford Progeria‚ this disease classifies only 50 patients worldwide. In 2007‚ the Children’s Hospital Boston aimed at enhancing the life for children with Progeria. The Progeria Research Foundation (PRF) and many other agencies aided the hospital with this goal of finding treatments
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known dieseases in class one diesease that striked me as i was watching a tv show last year was progeria. Progeria is derived from the Greek work meaning prematurely old. Jonathan Hutchinson and Hastings Gilford discovered the syndrome in 1886. The name Hutchinson Gilford progeria syndrome existed because of this. doctors have discovered a single gene mutation responsible for Hutchinson-Gilford progeria syndrome. The gene is called lamin A this is the protein necessary for holding the center of a
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Progeria Jessica Perry Canterbury School of Florida Progeria is an extremely rare genetic disease which causes young children to age very rapidly. This condition is from the Greek word for old age “geras.” It is estimated that it only affects one in four million newborns throughout the world. A newborn typically will appear normal. Within the year the child’s growth rate decreases and they look shorter and weigh much less than other children around their age. The
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gene mutation such as this is Progeria. This disorder is an unfortunate one that may occur in two forms‚ either Hutchison-Gilford Progeria or Werner syndrome. Not only do they affect the bone structure and appearance of the child‚ but they substantially shorten their life spans. Hutchison-Gilford disorder was first discovered and described by John Hutchison in 1886. However‚ in 1904 Hastings Gilford named the disorder Progeria after doing some of his own research on it (Malady). Approximately
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Progeria‚ meaning "before" or "premature"‚ and "gēras"‚ meaning "old age". The disorder has a very low incidence rate‚ occurring in an estimated 1 per 8 million live births. Those born with progeria typically live to their mid teens to early twenties. It is a genetic condition that occurs as a new mutation‚ and is rarely inherited‚ as carriers usually do not live to reproduce. Although the term progeria applies strictly speaking to all diseases characterized by premature aging symptoms‚ and is often
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named after the scientists who discovered the disease in 1886‚ Dr. Jonathon Hutchinson and Dr. Hastings Gilford. Progeria occurs in 1 out of 4-8 million newborns. The name comes from the Greek word “Progeria”‚ which means “prematurely old”. This syndrome is an autosomal dominant condition‚ which means the gene has to be inherited from only one parent for the child to be affected. Progeria occurs when a child is born with a defective gene called LMNA. The gene LMNA is found in Chromosome 1. LMNA is
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Hutchinson-Gilford Syndrome‚ commonly referred to as progeria‚ is a disease that has this effect on a significant amount of children around the world. Although there are many different forms of progeria‚ Hutchinson-Gilford Progeria Syndrome is the classic type. The name progeria comes from Greek origin and means “prematurely old”. Those who suffer from this disease take on the effects of early aging. Although their bodies begin to age early in life‚ children with progeria maintain an intelligence level that is
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