complexation of agomelatine with HP β-CD to enhance aqueous solubility and then to its mucoadhesive tablet for buccal delivery of agomelatine. A major hurdle that has prevented the commercialization of many promising poorly soluble drug candidates is dissolution rate-limited bioavailability or permeation rate-limited bioavailability. Buccal route of administration provides better penetration of therapeutic and diagnostic agents‚ and a reduced risk in comparison to conventional treatments
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Ethical Theories- Pros and Cons Katherine Bryson ETH/316 October 15‚ 2012 Mark Cobia Ethical Theories- Pros and Cons The similarities between the virtue theory‚ the utilitarianism theory and deontological theory are that they all support good and responsibility. Virtue theory not only concentrates on how an individual acts but also what a person should strive to be‚ for example a religious figure may personify perfection when in the public when they really should strive for that perfection
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Competitive Advantage and Pro Sports William Brown MGT/488 STRATEGIC BUSINESS MANAGEMENT AND PLANNING February 5‚ 2010 Dr. Bob Amason Competitive Advantage and Pro Sports Are they Valuable? Yes‚ Pete Carol has been valuable to the brand in the past. He is a brand in himself. This year the Trojans have suffered without him‚ his philosophy‚ and his charm. One may highlight that he fled to avoid the NCAA -scandal so perhaps the team is better but a prominent coach adds sparkle to the
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The Pros of Same-Sex Education Socially‚ same-sex schools are emotionally easier on students. Stereotypes based on gender are not a huge issue in these settings. Girls are more outspoken and competitive when boys are not around to tease them. They also feel more comfortable participating in sports and traditionally male dominated fields when boys are not watching. Conversely‚ boys become less competitive and collaborate more because they don’t have to worry about girls’ opinions of them. They can
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Living in Megacities Pros: 1. The quality of life in such megalopolises is better than was predicted. Life expectancy is longer in the big cities than in smaller ones or in the countryside. Urban dwellers are more likely to have good sewage disposal and running water than are their rural compatriots. And cities tend to offer superior medical care‚ greater educational opportunities and more jobs. 2. In the city people have more chances to be employed‚ as the range of jobs is greater than
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Top 10 Pros and Cons Should the death penalty be allowed? The PRO and CON statements below give a five minute introduction to the death penalty debate. (Read more information about our one star to five star Theoretical Credibility System) 1. Morality 2. Constitutionality 3. Deterrence 4. Retribution 5. Irrevocable Mistakes 6. Cost of Death vs. Life in Prison 7. Race 8. Income Level 9. Attorney Quality 10. Physicians at Execution PRO Death Penalty CON Death Penalty 1. Morality PRO:
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Transgenic application‚ advanced gene splicing techniques which are all part of biotechnology gave rise to genetically modified organisms (GMOs) and moving genes also referred to as genetic engineering (GE). These new genetically science allows genetic material from one species to be transferred into another species‚ creating transgenic organism with combinations of gene from plants‚ animals‚ bacterial or even a viral gene pools. This intentional transfer of genetic material has in turn brought biotechnology
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nutritional value and are just plain unnecessary. The next add on to my version of EBT is at least one person on the EBT card has a full-time job and show proof of employment every two months‚ along with everyone in the house hold being tested for drug use. I feel that if I’m going to have to help pay for their food then they should have restrictions. For those who read my paper I’d be interested in your ideas on restrictions for
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as the animals they were cloned from‚ which gives scientists an incredible advantage. The cloned animals could assist as the perfect control subject for testing‚ meaning they would be able to compare results to how the animal was originally (“Pros and Cons of Animal Cloning”). Scientists have used animal models in clinical trials before‚ but with cloning they could do twice of the research. Mice are an example that scientist have used to genetically alter to make them carriers of disease and are
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President John F. Kennedy‚ the Gun Control Act was established prohibiting mail order sales of rifles and shotguns‚ increasing license requirements for sellers and broadening the list of persons prohibited from owning a firearm to include convicted felons‚ drug users and the mentally incompetent. Further laws have continued to be created as time has passed‚ shaping to the needs of the county at the time. Close to the beginning of the 20th century‚ The Brady Handgun Violence Protection Act was passed requiring
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