Coagulation factor V (FV) circulates in the bloodstream in an inactive form (procofactor) and is activated to factor Va (FVa) by thrombin. Thrombin cleaves away the large inhibitory B-domain of FV which resolves the molecule into a heterodimer that is stabilized through non-covalent interactions between heavy (A1-A2) and light (A3-C1-C2) chains. A recombinantly expressed truncated B-domain variant of factor V (FV-DT) exhibits constitutive FVa-like activity even in the absence of proteolysis. FV maintains
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Infrastructure Hungary possesses an excellent public transport system which consists of the rail system‚ highways‚ and waterways. The rail system is owned and operated by the state‚ which also connects all major cities in Hungary and international destinations. Hungary has permanent navigable waterways‚ which includes the Danube River that flows north to south‚ through the center of Hungary. With these advantages‚ the Danube provides low-cost mode to transport passengers and domestic freight. This
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RUNNING HEAD: Understanding Enzymes Understanding Enzymes Amanda Chung Blanche Ely High School Abstract The researcher conducted this experiment in order to investigate how various factors effected enzymes. Those factors were the concentration of the enzyme‚ the temperature it had to work in‚ and the pH level of the solutions as well. All three were hypothesized to speed up the rate at which the enzyme acted. A series of several tests were carried out to find the answer to each problem
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1. (a) Privilege is defined as a favor or right granted to some people‚ but not to everyone. (b) Power is defined as strength‚ ability‚ or a driving force. (c) Difference is defined as the way in which two things are not the same. (d) According to MacIntosh there are two types of privileges. The first is based on what she calls "unearned entitlements‚" which are things that all people should have. Some examples are feeling safe in a public place or working in a place where they feel that they belong
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What is "Small" Business? In addition to how a business is organized legally‚ size is also a way to classifying businesses. A small business is generally defined as any independently owned business with fewer than 500 employees that is not dominant in its industry. The Small Business Administration (SBA) is responsible for issuing the specific criteria that render a business a small business. These criteria vary widely by industry. As recently as 2010‚ in an effort to make more businesses eligible
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Critical Thinking and Ethics THE RELATIONSHIP BETWEEN CRITICAL THINKING AND ETHICS Critical thinking is an individual’s form of judgment that has a particular purpose and reflective judgment. When individuals use critical thinking they reach a decision or solves an issue of judging what to believe or what to do‚ but reaches this conclusion in a thoughtful way. Critical thinking is a tool that individuals can use to evaluate incoming information. On the other hand‚ ethics is a branch of philosophy
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PROTEIN Prior to completing the lab experiment‚ it was predicted that whipping cream‚ soy milk‚ and the flour solution would all contain proteins. Looking back at the collected observations it can be concluded that the hypothesized statements were all deemed accurate. However‚ corn syrup was the only substance that did not test positive for proteins. This abnormality was researched‚ and it is now clear why only three out of the four substances tested positive for proteins. To start‚ it was hypothesized
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agrin-like protein (AGRINL) and EGF-like‚ fibronectin type-III and laminin G-like domain-containing protein (EGFLAM)‚ is a fibrous protein that in humans is encoded by the EGFLAM gene. Pikachurin is a dystroglycan-interacting protein which has an essential role in the precise interactions between the photoreceptor ribbon synapse and the bipolar dendrites. The binding with dystroglycan (DG) depends on several factors (glycosylation of DG‚ presence of divalent cations‚ presence of other proteins). A non-correct
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Full Report on Exercise 4.2 ESTIMATION OF PROTEIN CONCENTRATION BY SPECTROPHOTOMETRY And Exercise 4.3 GEL FILTRATION CHROMATOGRAPHY Joel Don M. Untalan CHEM 160.1 – 1L AY 2013 – 2014 Groupmates: Sonette Yao Kristopher Quilan Laboratory Instructor Carmelo C. Briones I. Introduction Analyzing proteins in determination of protein concentration by spectrophotometry is important. It determines to what concentration of a certain protein is in a crude sample. In this technique‚ a wide
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Risk Factors are actions or conditions that an individual or group of individuals do that increases their risk of developing a disease. The disease isn’t just limited to infectious diseases but can also include chronic disease such as obesity. Risk Factors can either be modifiable‚ non modifiable‚ and also social/environmental risk factors. Modifiable risk factors mean you can take measures by altering ones life to remove the potential risk of developing a disease. Non modifiable works in the opposite
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