eukaryotic proteins in prokaryotic cells occasionally results in instability or lack of biological activity. What are three of the post-translational modifications that eukaryotic cells can carry out that prokaryotic cells cannot? a) b) c) Correct disulfide bond formation Proteolytic cleavage of inactive precursor See Fig 7.1 p241 for cleavage of preproinsulin Glycosylation - addition of sugar residues See Fig 7.2‚ 7.3 p. 242‚243 in text Modification of amino acids in protein Phosphorylation
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-othapy denotes a disease or disorder. A proteinopathy is any disease caused by a malformed protein. 2. Where are tau proteins found? What do they do here? Tau proteins are found inside of nerve cells. Tau proteins perform the function of stabilizing microtubules. 3. What is an isoform? How many tau isoforms are there in the brain? An isoform is a protein that has the same function as another protein but is encoded by a different gene and may have small differences in its sequence. There are
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applied to the understanding of biological polymers and lipid membranes. The emphasis is on properly linking monomers and their polymers‚ and on the structural and functional diversity of the different polymer types. Particular attention is given to protein structure‚ because this is central to understanding subsequent chapters on metabolism‚ molecular biology‚ and molecular medicine. Multiple-Choice Questions 1) Humans and mice differ because A) their cells have different small organic molecules
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ABCT 1101/ABCT1D04 Introductory Life Science INTRODUCTORY LIFE SCIENCE At our 3rd lecture‚ we want to discuss • The building blocks of biological organisms – Carbohydrates‚ proteins‚ lipids and nucleic acids • Cell structure and function – Cell membrane‚ ER‚ Golgi‚ cytoskeleton‚ nucleus – Plant cell vs. animal cell Simple Chemistry for Life Science • Each element consists of one kind of atom. – An atom is the smallest unit of matter that still retains the properties of an element
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Name the 4 main Organic Molecules in Biochemistry. Describe each one‚ and provide an example. What are the “building blocks” of each molecule? For example‚ protein = Amino Acid. • Proteins - monomers are amino acids and proteins are used for various reasons in cell such as structure‚ defense‚ modification. An example of a protein is hemoglobin that red blood cells used to carry oxygen. • Carbohydrates - monomers are monosaccarides with the general formula of CH20. Carbohydrates can
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initiation codon and it initiates the translation process‚ which is necessary for formation of a protein. The last codon is known as a Stop codon as it stops the translation process to end the addition of amino acids to protein chain. In absence of Stop codon the protein formation is never completed as there would uninhibited addition of amino acids. What meaning do these mRNA codons have for protein synthesis? Explanation: The mRNA codon sequences specify for respective amino acid. More than
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com/od/geneticsglossary/g/DNA.htm"DNA or RNA) enclosed in a protein shell or coat. Viruses are extremely small‚ approximately 15 - 25 nanometers in diameter. Viruses: Genetic Material Viruses may have double-stranded DNA‚ double-stranded RNA‚ single-stranded DNA or single-stranded RNA. The type of genetic material found in a particular virus depends on the nature and function of the specific virus. The genetic material is not typically exposed but covered by a protein coat . The viral genome can consist of a
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proximity. An example would be a nerve cell releasing neurotransmitters. In autocrine signaling the cell that produces the ligand also contains the receptor for that ligand. This is how cancer cells work. In signaling by plasma membrane attached proteins‚ the target cell does something in response to direct contact from the signaling cell. 2) List examples of 1) steroid hormones and 2) amino acid derivatives that act as ligands. What are the catecholamines‚ and which amino acid are
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genetic information from DNA to protein in eukaryotic cells is called the central dogma of biology. The role of RNA in protein synthesis is extremely important as protein synthesis could not occur without RNA. Three forms of RNA exist solely to create proteins. Through a process known as translation‚ RNA constructs the proteins necessary to sustain life. Spliceosomes Process pre-mRNA by splicing out intronic nucleic acids producing mRNA which is then translated to protein in ribosomes. Codons are three
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Messenger RNA is the “mirror image” of the DNA that encodes the amino acid sequence for the protein specified by the gene. The Transfer RNA transfers the amino acids to the ribosomes from coded messages. Ribosomal RNA helps build the proteins on the ribosome. d. The reason that so many RNA molecules are produced more than DNA molecules because you only have two copies of DNA in one cell. If only two proteins could be produced at a time it would take the cell a much longer time to do the functions
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