others. Concept 7.1 Cellular membranes are fluid mosaics of lipids and proteins The main macromolecules in membranes are lipids and proteins‚ but carbohydrates are also important. The most abundant lipids are phospholipids. Phospholipids and most other membrane constituents are amphipathic molecules. Amphipathic molecules have both hydrophobic regions and hydrophilic regions. The arrangement of phospholipids and proteins in biological membranes is described by the fluid mosaic model. Membrane
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Group 4- DAH Manalo‚ Paul Manggahas‚ Luis Manio‚ Love Joy Masigan‚ Stephanie Kyra Mendiola‚ Roxanne Mendoza‚ Jullienda August 2014 I. Structure Myoglobin is almost similar in structures with hemoglobin except on the heme groups attached to it and to the presence of amino acids. Myoglobin only seems like a quarter of hemoglobin. Myoglobin has a molecular weight of 18‚ 000. It has a component of a single polypeptide chain folded into 8 α- helical structure‚ 153 amino acids and one
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the large (L)‚ middle (M) and small (S) envelope proteins‚ respectively (Tiollais et al.‚ 1985) . The S protein is 226 amino acids long‚ has a molecular mass of 25 kDa and shares DNA and amino acid sequence as the C-terminus of the M and L protein. The M protein has a 55-amino acid extension to the S protein at its N-terminus‚ giving it a molecular mass of 31 kDa‚ while the L protein a further 108-119-amino acid extention to the M protein at its N-terminus and a molecular mass of 43
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1. Membrane lipid 2. Membrane skeleton 3. Peripheral proteins 4. Integral proteins 2. RBC metabolism 1. Glycolytic (Embden-Meyerhof) pathway 2. Hexose monophosphate shunt 3. Rapoport-Luebering pathway 2.4 Methemoglobin reductase pathwa 3. Hemoglobin 3.1 Hemoglobin structure 3.2 Hemoglobin synthesis 3.3 Genetic control of hemoglobin structure 3.4 Hemoglobin
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RABIES Abstract: Each year‚ approximately 55‚000 individuals worldwide die from an infection due to the rabies virus. Rabies is a life-threatening disease caused by an RNA virus that is usually transmitted to humans through bites from rabid animals. More recently‚ reports of transmission by means of organ transplantation have been reported. Since human rabies is nearly 100% fatal if prophylactic measures are not followed‚ an increased awareness of who should receive prophylaxis and
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Proteins provide our bodies with the amino acids that cannot be produced within the body. Through the process of digestion‚ food is broken down into essential amino acids that can be used for protein synthesis. In essence‚ proteins build up‚ maintain‚ and replace tissues in your body. For instance‚ proteins help make hemoglobin which carries oxygen to all the parts of your body. Proteins are broken down into amino acids during digestion. The amino acids can then be reused when the body needs protein
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The Elusive Prions and CJD: possible to treat? Introduction to Prion Disease Prion disease is an infectious neurodegenerative disease caused by a naturally occurring protein (PrPC) misfolding into an aberrant form (PrPSC) which aggregates and destroys neuronal tissue. PrPSC was originally posited by Stanley Prusiner to be the sole causative moiety in prion disease (Prion Theory)‚ however there is some evidence to suggest that unknown toxic intermediates‚ co-factors‚ and certain nucleic acids
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provides high capacity of binding area to analytes by its high density of ligand binding surface while it could be the possible risk factor to trigger the non-specific binding. The non-specific binding signals leads to inaccurate analysis of protein-protein interaction or kinetic study. 2) When a CM-5 chip is used‚ what parameters we have to optimize for the immobilization? (2 marks) 1.
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The goals of this experiment are to determine if the products derived from amide synthesis and Williamson Ether Synthesis are identical‚ and if one of the synthetic routes is more advantageous than the other. In Part 1‚ an attempt to synthesize acteophenetidin crystals by amide synthesis was made. We began by removing the colored impurities from the p-Phenetidine (reddish-brown) by placing 2g of the sample in 38 mL of hydrochloric acid and heating the solution to boiling point. Upon reaching just
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primary function. Macromolecules: a) Carbohydrates b) Proteins c) Lipids d) Nucleic acids (Total 8 marks: 1⁄2 mark for each correct answer) 6. Show how a peptide bond forms between the two amino acids‚ glycine and valine. Draw the structural formulas for the reactants and the product. Label the functional groups and linkages present. (5 marks) Glycine + valine → ? 7. 7. Chocolate milk has been a choice for many athletes‚ as it is a good source of protein‚ carbohydrates‚ and lipids. Suppose you were to
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