Lab 1: Synthesis of Aspirin Introduction: The purpose of this lab was to demonstrate the ability to easily alter the molecular structure of a compound to greatly increase its utility. In this case‚ an acetyl group was added to salicylic acid‚ a naturally occurring compound with significant pharmaceutical value. Without the addition of the acetyl group‚ salicylic acid is an irritant to the gastro-intestinal (GI) tract. Once the acetyl group is added via a simple reaction‚ acetylsalicylic
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EUROPEAN PHARMACOPOEIA 5.0 Acetylsalicylic acid TESTS Appearance of solution. Dissolve 1.0 g in 9 ml of alcohol R. The solution is clear (2.2.1) and colourless (2.2.2‚ Method II). Related substances. Examine by liquid chromatography (2.2.29). Prepare the solutions immediately before use. Test solution. Dissolve 0.10 g of the substance to be examined in acetonitrile for chromatography R and dilute to 10.0 ml with the same solvent. C. N‚N′-diacetyl-L-cystine‚ Reference solution (a).
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Lab Report Synthesis and Characterization of Aspirin (Acetylsalicylic Acid) The Synthesis and Characterization of Aspirin (Acetylsalicylic Acid). Summary: In this experiment‚ we produced 4.21 g of acetylsalicylic acid. Our theoretical yield was calculated to be 5.22 g. Therefore our % yield was determined to be 80.6%. The experimental boiling point range of acetylsalicylic acid was found to be 130-132° C. The true melting point of acetylsalicylic acid is 135° C‚ therefore our percent
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OF ASPIRIN Aspirin in general is a safe drug but the ability to prevent blood clots is connected to some side effects. Aspirin can cause firstly stomach irritation. That’s means aspirin can irritate your stomach which has as a result pain‚ nausea‚ vomiting or hearburn. Sometimes can have other symptoms like bleeding‚ holes in stomach or intestines. In order to minimize these problems it should be better to have a full stomach. Also another problem that comes from aspirin can
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Formal Report no. 1 Synthesis of Aspirin Chemical Principles Aspirin is most widely sold over-the-counter drug. It has the ability to reduce fever (an antipyretic)‚ to reduce pain (an analgesic)‚ and to reduce swelling‚ soreness‚ and redness (an anti-inflammatory agent). Much of this is believed to be due to decreased production of prostaglandins and thromboxanes. Aspirin’s ability to suppress the production of prostaglandins and thromboxanes is due to its irreversible inactivation of the cyclooxygenase (COX)
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Reshmi Nair Title: Determination of Aspirin through back titration. Aim: To determine the concentration of Aspirin in a tablet using NaOH and Hcl. Research Question: What is the concentration of Aspirin in a normal tablet? Background: Aspirin is the general name for acetylsalicylic acid (ASA); it is also the trademark of the drug produced by Bayer in Germany. In eighty countries‚ aspirin is a registered trademark‚ but in other places the term aspirin refers to ASA by itself or as an ingredient
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Our words have a strong power. With our speech we have the ability to make worlds or break worlds. The Torah’s laws of speech make it possible for people to live together in peace and build close relationships. One who wants to create a serene home with a pleasant atmosphere should incorporate all the laws of shmiras haloshon into his actions and teach his family to follow suit. We deal with so many people and situations on a daily basis that frustration with others is inevitable. The laws of shmiras
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EXPERIMENT A PREPARATION OF ASPIRIN Abstract This report gives a detailed account of the experimental preparation of aspirin in a laboratory environment as well as some basic industrial background on the product. It also contains information about safety precautions put in place to ensure the safety of the team who carried out the experiment. All results obtained have been included as well as a detailed analysis of what they represent alongside any improvements to the method used. Introduction
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Aspirin or acetylsalicylate acid is a compound that is widely used in medicine. The use of aspirin in medicine began long before the active reagent was removed from its natural source. The first documented use of aspirin was found in the writings of Hippocrates‚ the so called father of medicine. Hippocrates prescribed that willow bark could be used to remedy a wide range of conditions such as pain‚ fever and inflammation. Scientists began to seek to extract the active compound from willow tree bark
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Synthesis of Aspirin Learning Goals 1. To synthesize aspirin from salicylic acid and acetic anhydride. 2. To purify the crude product by Recrystallization. Introduction Most drugs are chemical compounds which are described as "organic compounds" because they are comprised primarily of the elements carbon‚ hydrogen and oxygen. The present experiment will be the synthesis of a familiar organic compound called aspirin. The common chemical name is acetylsalicylic acid. Aspirin‚ the most
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