Title: Reaction of Iodoethane with Sodium Saccharin- Ambient Nucleophile Dates Performed: February 21 + 28‚ 2013 Date Submitted: March 14‚ 2013 Abstract: The product ratio of N-ethylsaccharin to O-ethylsaccharin that occurred due to alkylation with iodoethane at 80 oC was determined to be 81.5% to 18.5%‚ respectively‚ based on an analysis of the 1H NMR spectrum that was collected. The melting point range of 87.8-94.7 oC also indicated that the mixture was largely composed of N-ethylsaccharin
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alkylate sodium saccharin to N-ethylsaccharin with iodoethane in an aprotic solvent N‚N dimethylformamide. Nucleophiles in this experiment will react better in an aprotic solvent. Aprotic solvents have dipoles due to its polar bonds but they do not have H atoms that can be donated into a H-bond. The anions which are the O- and N- of sodium saccharin are not solvated therefore are “naked” and the reaction is not inhibited and preceded in an accelerated rate. The reaction was an SN2 reaction. Since the
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Saccharin is one of the most disputed sugar substitutes in the United States today. Since 1977‚ it has been regarded as potentially carcinogenic ("Saccharin"‚ 1999). The sweetness of saccharin compared to sugarcane is utterly amazing. When measured up to sugarcane‚ saccharin is 550 times as sweet in its pure state. Also‚ it is estimated to have a sweetening power of 375 times that of sugar ("Saccharin"‚ 2000)! This drug may be amazing‚ but some people say that it causes a dangerous disease‚
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Publication No. 91860 Rate of Reaction of Sodium Thiosulfate and Hydrochloric Acid Rate Laws Introduction The purpose of this demonstration is to investigate the effect of sodium thiosulfate concentration on the rate of reaction of sodium thiosulfate with hydrochloric acid. The reaction‚ which produces solid sulfur‚ will be followed by measuring the time needed for the reaction mixture to become opaque. The results will be analyzed graphically to determine the order of reaction— the mathematical relationship
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to carry out the alkylation of sodium saccharin with iodo-ethane and analyze the product mixture to determine the structure of the major product. Sodium saccharin is made from the base catalyzed de protonation of saccharin. This nucleophilic reaction is special because the nucleophilic atom can be oxygen or nitrogen and the leaving group is iodide ion. The solvent used in this reaction is very important for determining the rate of nucleophilic substitution reaction. Polar protic solvents such
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Concentrations of HCl on the Rate of Reaction Between HCl and Sodium Thiosulfate Chemistry Lab report Aim: The aim of this experiment is to determine how concentrations of HCl acid affect the rate of reaction when reacted with Sodium Thiosulfate (Na2S2O3). This experiment would require measuring the mass of the reaction over a period of time to be able to determine the rate of the reaction. Safety Precautions: In this experiment‚ SO2 gas is produced from the reaction between Sodium Thiosulfate and HCl‚ and
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Results and discussion: I. a. How would you compare that relative reactivity of Na and k -Sodium and potassium react somewhat similar when reacting with water however they are slightly different. Sodium moves because of the hydrogen coming off of it and has a low melting point while potassium’s reaction is faster and enough heat is produced to set light to the hydrogen coming off of it. Each leaves a pink color hue in the water. Discuss the similarities and differences in the behavior of the metals
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Chemical Reactions- Sodium Hydroxide A chemical reaction is a change where two or more substances are changed into a new substance. You can identify a chemical reaction by colour change‚ effervescence (bubbles)‚ when light or heat given off‚ and the change is usually irreversible. There are 6 main types of chemical reactions- combustion (often called burning)‚ synthesis‚ decomposition‚ neutralization‚ single replacement and double replacement. A combustion reaction is a reaction with oxygen‚ and
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E. Reactions of Aldehydes and Ketones with Sodium Hydroxide Objectives: To know the reactions of aldehydes and ketones with sodium hydroxide a) State the function of Sodium Hydroxide in the test. Sodium hydroxide (NaOH) is the oxidizing agent. b) What are the principles involved in the test? What is its purpose? Cannizzaro reaction is a reaction that uses a strong base‚ such as sodium hydroxide‚ which results to the formation of a carboxylic acid (or its corresponding salt) and an alcohol
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SODIUM gSodium is a chemical element with the symbol Na (from Latin: natrium) and atomic number 11. It is a soft‚ silver-white‚ highly reactive metal and is a member of the alkali metals; its only stable isotope is 23Na. The free metal does not occur in nature‚ but instead must be prepared from its compounds; it was first isolated by Humphry Davy in 1807 by the electrolysis of sodium hydroxide. Sodium is the sixth most abundant element in the Earth’s crust‚ and exists in numerous minerals such
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