objective of this experiment was to illustrate electrophilic aromatic substitution by synthesizing p-nitroanilide (as well as ortho) from acetanilide by nitration. The para form was separated from the ortho form based on solubility properties using recrystallization techniques. Synthetic equations: Physical Properties & Hazards of Reagents/Products: (all taken from Sigma-Aldrich website) Acetanilide MM = 135.16 g/mol Melting point = 113-115°C Hazards: acute toxicity Sulfuric acid MM = 98
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product was 69.03%. Following recrystallization of the product using xylene and vacuum filtration‚ a percent yield of 37.42% for the recrystallized product was collected. This was low due to the fact that some of the crude product was not recrystallized and was instead used to take a melting point of the crude product. It was also low due to several of the crystals being stuck inside the flask and not going into the funnel. The percent recovery from recrystallization was 54.21%. The melting point
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Recrystallization of Methyl 3-nitrobenzoate Santiago Horta‚ Daniella I School of Chemistry and Biochemistry‚ Georgia Institute of Technology Atlanta‚ GA 30332 Submitted: 18 February 2015 In this experiment‚ the product of a nitration will be purified by recrystallization using a selected solvent. Methyl benzoate is treated with nitric acid and sulfuric acid to obtain methyl 3-benzoate‚ which will be mixed with a solvent that will dissolve the product at its boiling temperature but not at
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The precipitate was allowed to dry for recrystallization. The product was removed from the filter paper and weighed. The weight of the product was 1.445g. NMR was conducted by mixing the dry product (0.35mg) with duderated chloroform (0.50ml) and mixing until the precipitate dissolved. The sample was then placed into the NMR. The NMR spectrum confirmed the product was benzocaine. The remainder of the sample was placed into a 250ml beaker for recrystallization. Methanol and deionized water were added
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C6H5NHCOCH3 + CH3COOH (http://www.mendelset.com/articles/680/preparation-recrystallization-acetanilide) (regensburg.de/Fakultaeten/nat_Fak_IV/Organische_Chemie/Didaktik/Keusch/Grafik/box_brom_ar1.gif) The second figure illustrates the process used in the laboratory to form bromoacetanilide. Recrystallization is of key importance in the experiment because this method is used to obtain the crystals. Recrystallization is a purification technique that removes impurities from a sample. An impure
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Synthesis of Dulcin Objective: The main objective of this lab is to gain experience at a typical synthesis and semi-microscale recrystallization. Discussion Questions: 1) How fast should the temperature be raised when determining a melting point? When can the temperature be raised more quickly? 2) If there is an Impurity present in a sample‚ what is the effect on the melting point? 3) Explain why a) salt‚ spread on roads in the winter‚ helps prevent icing in‚ for instance‚ southern
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HEAT TREATMENT OF COPPER AND COPPER ALLOYS COPPER AND COPPER ALLOYS: Copper and its alloys are widely used in many products that are used in our everyday life. They have excellent properties such as electrical and thermal conductivity good strength. They have high corrosion resistance and fatigue resistance. Copper is a non-magnetic material. Pure Copper is soft and used widely in wires and cables and is extensively used for passage of electricity. Copper is used in the building construction.
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Analysis The crude product (aspirin) was purified in the last lab‚ using recrystallization‚ in which we dissolved the crude product with hot ethanol. We then added 25 mL of water until the product reformed (the solution became cloudy white) and redissolved the solid with hot ethanol. The solution was allowed to cool for a week‚ and crystals of purified solid were formed. In order to analyze this purified product‚ we determined the melting point by placing a small sample of the aspirin in a
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the impurities should be insoluble in the solvent. 2.> How were soluble impurities removed from the derivative? [ANS] By soaking the impure derivative in 1 cm3 of methanol and resume suction. Repeat this for about 2 times. 3.> In the recrystallization procedure‚ why were the crystals dissolved in only the minimum amount of
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is the purpose of determining the melting point in this lab? 5. Why is this method not used for finding the melting points of inorganic ionic compounds? Recrystallization Questions 1. What is the purpose of recrystallization? It is the primary method of purifying crude solid compounds. 2. What is the recrystallization method based on? It is a process based on the differences in solubilities of solids in a given solvent system. 3. How can you increase the solubility of
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