Sickle cell anemia (SCA) is a genetic disorder that is hereditary. It affects the blood‚ and is caused when the hemoglobin in blood cells are deprived in oxygen from the proteins. These cause normal round blood cells‚ to have are rigid sickle shape. People affected by SCA have a higher risk of death‚ stroke‚ severe attacks‚ and severe rushes of pain. James Herrick discovered an anemia‚ and found bizarre sickle-shaped cells in 1910. A treatment for the disease was discovered in the 1920s by E. Vernon
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Sickle cell anemia was first discovered in the year of 1910. A young man by the name Walter Clement Noel from the island of Grenada‚ studied in Chicago. He went to Dr. James B. Herrick‚ whom was a cardiologist‚ with symptoms of anemia‚ who assigned Dr. Ernest Irons to the case. There Dr. Irons noticed that Noel’s red blood cells were the shape of a sickle. Although sickle cell anemia has occurred in Africa for thousands of years‚ Dr. Herrick was the first to provide a formal description of sickle
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Alexandria Agee Ms. Songer AP Biology February 16 2015 Sickle Cell Anemia: Case Study Summary Sickle Cell Anemia is a painful diseases that is caused by a mutation in the protein called hemoglobin which helps carry oxygen in red blood cells. Because of the mutation‚ the hemoglobin is shaped oddly which results in pain because it is hard for the blood to travel throughout the body and anemia because of the lack of oxygen in the blood. A person can only have this disease if both parents are carriers
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Terminology 1 18‚ April 2013 Sickle Cell Anemia Sickle-cell Anemia is a genetic blood disorder caused by the presence of an abnormal form of hemoglobin molecules in which the red blood cells loose their disc-shape and become crescent shaped. The shape also known as “hemoglobin S”. unlike normal red cells which are usually smooth and malleable‚ tend to collect after releasing oxygen‚ and cannot squeeze through small blood vessels. The organs are then deprived of blood and oxygen. The basic life-span
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Introduction - sickle cell anemia The first suggestion that genes might provide the information for all proteins came from Linus Pauling’s lab at Caltech. He and his student Harvey Itano studied hemoglobin‚ the protein in red blood cells that transports oxygen from the lung to metabolically active tissues‚ like muscle‚ where it is needed. In particular‚ they focused on the hemoglobin of people with sickle-cell disease‚ also known as sickle-cell anemia‚ a genetic disorder common in Africans‚ and
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Glucose-6-phosphate dehydrogenase (G-6-PD) deficiency is a hereditary condition in which red blood cells break down when the body is exposed to certain drugs or the stress of infection. It is an X-linked recessive hereditary disease characterised by abnormally low levels of glucose-6-phosphate dehydrogenase (abbreviated G6PD or G6PDH)‚ a metabolic enzyme involved in the pentose phosphate pathway‚ especially important in red blood cell metabolism. G6PD deficiency is the most common human enzyme defect. Individuals
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Case Study 97 1. Sickle cell disease is a group of disorders that affects hemoglobin‚ the molecule in red blood cells that delivers oxygen to cells throughout the body. People with this disorder have atypical hemoglobin molecules called hemoglobin S‚ which can distort red blood cells into a sickle‚ or crescent‚ shape. SCD affects millions of people worldwide‚ particularly those with African‚ Spanish‚ Mediterranean‚ and Indian ancestry. Some 120‚000 infants are born with SCD every year worldwide
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WATER FLOW ACROSS CELL MEMBRANES pg. 1 Lab Report 1 Water Flow Across Semi-Permeable Membranes WATER FLOW ACROSS CELL MEMBRANES pg.2 WATER FLOW ACROSS CELL MEMBRANES The movement of water across semi-permeable membranes as it relates to the laws of thermodynamics and energy flow with the diffusion
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Physiology ------------------------------------------------- Determine Blood Group Using Eldon Card ------------------------------------------------- The Experiment Zlata Jasevits Nursing Studies ‘A’ 2nd February 2009 Contents Introduction 3 Blood Structure 3 Blood Group Systems 4 ABO system: 4 Rhesus System: 5 Blood Transfusion 6 ABO Alleles and Genetic Inheritance Patterns 6 The
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Sickle cell anemia is a genetic disease that affects the shape and functionality of red blood cells. It is caused by a mutation in the DNA of the protein‚ hemoglobin‚ specifically in the beta chain. There are 531 base pairs in this DNA strand. Substitution or point mutation occurs‚ causing “GAG” to become “GTG”. This results in valine being created instead of glutamate. The mutation causes the hemoglobin to cling together in low oxygen levels and the red blood cell changes shape‚ preventing it from
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