history and past medical history significant? It is not related to the ankle injury; however‚ past medical history shows asthma‚ eczema (allergy) and oral thrush due to the use of inhaled beclomethasone. 2) What is the role of salbutamol in the treatment of asthma? Salbutamol is short acting beta agonist‚ which symptomatically relieves the asthmatic attacks by bronchodilation of bronchi. Acts within minutes 3) What is the role of beclomethasone in the treatment of asthma? A- To reduce the inflammation
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Abstract The scope of this paper focuses on Salbutamol as a drug and the mechanisms behind; 1) The drug function. 2) Development of drug resistance. 3) The clinical features of drug resistant individuals. 4) How to diagnose them. 5) Management of these patients. Salbutamol resistance Salbutamol is a beta 2 adrenergic receptor agonist that is short acting and used in the management of conditions that cause bronchospasms/bronchoconstriction. These conditions mainly include
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hundred years of research has been put into the development of introducing the right agent triggering a specific response; Salbutamol as a ventolin inhaler‚ a β2-adrenoceptor agonist. This research report addresses the main compound that was considered as a “hit” in reversing the airway obstruction and why other compounds such as epinephrine and isoprenaline were neglected over salbutamol. A compound known as epinephrine in adrenaline injection was first addressed for the treatment of asthma in 1903
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This is a case study on a 76 year old man.Mr Alan Chari(pseudonym used to protect the identity of a patient)‚was admitted over night in my department.He is a divorcee who stays with son.He is a retired teacher and his son is permanently employed by a local company as an electrician.He is independent with activities of daily livings but is occasionally limited by his ill health.He used to be a heavy smoker .After realising the burden COPD has on general New Zealand population ‚affecting about15%
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sound will be normal * Expiration phase of breathing will be normal and effortless * Patient will verbalize ease in breathing. | To administer Salbutamol 5 mg by nebulizer To assess patient’s chest for normal breath sounds | * Salbutamol is a selective Beta2 adrenoceptor agonist. * To evaluate effect of the intervention | * 0.5 mls of Salbutamol made up to 2 mls with water for injection and administered through nebulizer * Patients chest ausculted | Goal fully met * Chest is clear
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Failure to respond satisfactorily Requirement for ventilation Emergency management If improving 40-60% O2 • prednisolone 40-50mg/ 24hrs PO • Nebulized salbutamol every 4hrs • Monitor peak flow • Emergency management If not improving after 15mins Continue 100% O2 • Repeat steroids • Salbutamol nebulizers every 15min or 10mg continuous per hour • Ipratropium 0.5mg every 4-6hrs • Emergency management If patient still not improving at >30mins Consider MgSO4 1.2-2g IV
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Pharmacology The ED consultant prescribes inhaled Salbutamol‚ inhaled Ipratropium as well as PO Prednisolone to Jessica. As the symptoms of asthma result from a combination of inflammation and bronchoconstriction‚ the pharmacological treatment focuses on anti-inflammation by using glucocorticoids and bronchodilation by using β2 agonists. Salbutamol Salbutamol helps to open up the airways and so relieves the symptoms of bronchospasm. Salbutamol is a short acting β2 adrenergic agonists. It takes
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morbidities (+) Smoking (18 packs year smoking) (+) occasional alcoholic beverage drinker Works as a call center agent 1week PTA: Symptoms: Daily Cough that worsens at night Chest Tightness Weezing and Difficulty in Breathing Patient was using salbutamol inhaler as needed and prednisone 2mg tablet. Patient is also complaining of painful urination‚ sore throat and foul vaginal discharge. PAST MEDICAL HISTORY FAMILY MEDICAL HISTORY (-) HTN (+) ASTHMA (-) DM (+)Allergies with nuts amd acetamenophen
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Exam Case Scenario Pathophysiology of Asthma Asthma is a chronic lung disease characterized by episodes in which the bronchioles constrict due to oversensitivity. In asthma‚ the airways (bronchioles) constrict making it difficult to get air in or out of the lungs. Breathlessness is the main symptom. The bronchi and bronchioles become inflamed and constricted. Asthmatics usually react to triggers. Triggers are substances and situations that would not normally trouble an asthma free person. Asthma
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the findings of Jackson et al.‚ (2011)‚ this could have triggered Geronimo’s acute exacerbation of asthma Lack of adherence to medication is another trigger for acute exacerbation of asthma (Jackson et al.‚ 2011). Without his nightly dose of Salbutamol over the last three days‚ Geronimo would experience difficulty maintaining a patent airway. Studies have shown that to prevent acute exacerbations‚ individuals should
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