MHC and Organ Transplant Paper BIO/402 April 22‚ 2013 MHC and Organ Transplant Paper There are a few routes that sensitization to non-self human leukocyte antigens (HLA) occurs (Fuggle & Martin‚ 2008). This article shows that 23% of renal patients that are awaiting transplantation are sensitized. More females than males have the HLA antigen. It also shows that first time transplants have less HLA antibodies than those that have had transplants in the past. Several approaches to transplant
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mean+2 SD were used (Table 4). Any OD value from each ELISA assay that equaled or exceeded the cut-off value was regarded as positive for leptospirosis infection and sensitivity (%) of the assay was calculated. Specificity (%) of the assay was calculated based on the number of control group below the calculated cut-off. The sensitivity of the serological assay‚ based on cut-off
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often inaccurate. The sensitivity of the human eye in interpreting large numbers of images decreases with increasing number of cases‚ particularly when only a small number of those images shows abnormalities. Therefore‚ it is useful to construct computer systems to aid early diagnosis of breast cancer with mammography. An automated computer system could evaluate all mammograms and point out the areas which are detected as abnormal. Ideally‚ if the sensitivity and specificity of the computer system
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present in 15% and only 31% of patients gave a typical history of acute appendicitis of vague peri-umbilical pain. The negative predictive values of white cell count and C-reactive protein for acute appendicitis were 28% and 50%‚ respectively. Sensitivity of the ultrasound to detect acute appendicitis was 60% with a negative predictive value of 31%; 30% of patients had complicated appendicitis. Histology results showed a normal appendix in 11% of patients. The 30-day mortality rate was 1.4%. Though
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Preliminary research of the current prevalence and management patterns of speech and language disorders is necessary before more in-depth epidemiologic analyses may be undertaken. One source of data for this type of study is electronic medical records (EMR) extracted from primary care clinics themselves. . EMRs provide patient histories in the form of diagnoses‚ prescriptions‚ billing information‚ referrals laboratory testing and other information recorded by the attending physician. Thus‚ EMRs present
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Four kinds of ELISA here are here illustrated as you may concern: Direct ELISA (1) Direct ELISAs involve attachment of the antigen to the solid phase‚ followed by an enzyme-labeled antibody. This type of assay generally makes measurement of crude samples difficult‚ since contaminating proteins compete for plastic binding sites. Indirect ELISA (2) Indirect ELISAs also involve attachment of the antigen to a solid phase‚ but in this case‚ the primary antibody is not labeled. An enzyme-conjugated
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2- What is the application of isozymes in clinical diagnosis? Give the names of some enzymes used in diagnostic kits. Testing the serum content is a very useful tool in the clinical diagnosis in general. Normally the enzymes are present inside the cells and the enzyme activity in the serum is very low. As the tissue gets damaged‚ due to a disease or infection‚ enzymes can be released from the damaged cells into the serum. As enzymes are biological catalysts‚ the detection of the presence and the
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care marks were divided in groups. Enfermagem methodology in gaining result includes socio-demographic and clinical data with the precipitating factors for each patients. Subsequently‚ second and third assessment obtained increase percentage of specificity and sensitivity.The identified intensive study and evaluation are significant for further research since this research limits in a single hospital. It does not give a wide range of assessment and variety of factors that might affect the condition
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consideration of poor mental health‚ including anxiety after giving birth. Some risk factors for poor mental health in the post-partum period can be identified prenatally; however prenatal screening tools developed to date have had poor sensitivity and specificity. The objective of this study was to develop a screening tool that identifies women at risk of distress‚ operationalized by elevated symptoms of depression and anxiety in the post-partum period using information collected in the prenatal
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