risking him or her having Sickle Cell Disease. What this is is it’s a disease that is genetically inherited and it involves the red blood cells. Mutations in the HBB gene cause this disease. This disease is inherited in an autosomal recessive pattern‚ which means both copies of the gene in each cell will have mutations. The parents of offspring with an autosomal recessive gene each carry one copy of the mutated gene. The blood cells form an abnormal crescent shape (normal cells are in a disk form)
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What is it? Sickle cell anemia is a type of blood disorder that can be inherited from parents. This is when red blood cells that are meant to carry oxygen around the body become deformed. Normal red blood cells are round and disc shaped‚ however‚ when they become sickle red blood cells‚ the deform and change shape into a crescent-like shape or sickle shape. The sickle cells have a shorter life-span than a healthy red blood cell and are not replaced as quickly as normal; this leads to a shortage
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SICKLE CELL ANEMIA Tina Thompson‚ Ashley Scott‚ Araceli Galindo‚ Roshanda Dixon‚ Kristen Wyatt‚ Kimberly Dennis What is Sickle Cell Anemia? Sickle cell anemia is a severe hemolytic anemia resulting in a sickle shaped hemoglobin molecule. It is an inherited disorder with some having sickle cell trait and some having sickle cell disease. The sickle hemoglobin gene is known as the HbS gene. It is found predominantly in people of African descent and occasionally in those of Mediterranean descent
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Observations: When Malaria is present and infects red blood cells‚ parasites can infect cells carrying defective hemoglobin which may result in death. Allele frequency changes over time depending on the pressures or circumstances facing a particular population. African populations are especially impacted by both malaria and sickle cell anemia. Depending on the impacted population‚ allele frequency often shifts and well suited organisms are likely to survive and allele frequencies can increase
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Sickle Cell Disease 11/17/14 This research informs the reader about Sickle cell disease. The goal is to raise awareness by describing what the disease is and where it originated. It gives advice on how to recognize signs in a crisis and how to help prevent any further symptoms. This focus uses facts from medical websites such as Web MD and Mayo Clinic. This research highlights every thing there is to know about sickle cell disease through detailed descriptions of where it comes from
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Introduction: Sickle-cell anaemia (SCA) also called Sickle-cell disease (SCD)‚ is a genetic blood disorder. It occurs due to a mutation in the haemoglobin gene. In sickle-cell anaemia‚ red blood cells become rigid‚ less flexible and adopt sickle shape. Sickle-cell disease occurs more commonly among people whose ancestors lived in tropical and sub-tropical sub-saharan regions. In Sickle cell disease‚ human blood contains both normal red blood cells and sickle-shaped cells. Sickle-cell disease causes
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Genetics- Word Count: 214 Sickle cell disease is a genetic blood disorder that plagues millions of people all over the world‚ the highest concentration is found among people of Sub-Saharan African descent. Sickle cell disease is caused by a mutation in the HBB gene located on chromosome 11. Hemoglobin in red blood cells is how oxygen is delivered to cells throughout the body and is composed of four subunits‚ two subunits of alpha- globin and two of beta- globin. The HBB gene provides the instructions
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TREATMENT OPTIONS There is NO cure for sickle cell disease‚ although new stem cell research is promising. Bone marrow transplant is a potential cure‚ however finding a matched sibling donor is difficult. Therefore treatment is primarily focused on management of symptoms and prevention of pain episodes. Hydroxyurea (a chemotherapeutic medication) is the only recognized treatment option for the prevention of vaso-occlusive crisis in SCD. It is a prescribed drug for adult patients
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‘How could natural selection increase the number of children born with sickle-cell disease in certain regions when these individuals are unlikely to survive and produce offspring?’ Darwin’s theory proposes that 3 conditions are a requisite for natural selection to occur. They are a struggle for existence of the offspring as they are competing for limited resources‚ variation within species which gives some individuals advantage over others hence better chance of survival and lastly inheritance
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General Biology 1 Sickle cell anemia is an inherited disease in which there aren’t enough healthy red blood cells to carry oxygen throughout the body . Where the cell is deformed is in the bone marrow ‚a gene in the bone marrow causes the blood cell to come out in a sickle cell shape because the hemoglobin in the defected body is abnormal‚ after it gives up the oxygen‚ bet together causeing the red blood cells to become to a sickle like shape.People with Sickle cell anemia have abnormal hemoglobin
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