Sickle cell disease and the hope of stem cell therapies; ethics in the treatment sickle cell. The past half century has been an era of rapid discoveries: from the humble beginnings of molecular biology‚ discovery of the structure of DNA‚ research on recombinant DNA‚ the discovery of the human embryonic stem cell (ESC)‚ the completion of the Human Genome Projects‚ mammalian cloning and the discovery of ntESCs (nuclear transfer ESCs) by somatic cell nuclear transfer and the ethical sigh of relief
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Abstract Transitional age youth between the ages of 15-18 who are battling chronic illnesses such as Sickle Cell Disease (SCD) traditionally have a hard time coping to their life style. This causes some to fall into depression and the outlook of the quality of life is decreased also. The eight week study will include six African- American boys and girls from an outpatient clinic that specializes in the medical care of persons with SCD. Participants will meet twice a week for an hour. The Children’s
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1. Macromolecules affected by Sickle Cell a. Hemoglobin: When the body is infected by Sickle Cell Disease‚ the primary structure of Hemoglobin is mutated. In the amino acid sequence‚ valine is substituted for glutamic acid causing sickle cell disease. This single mutation will eventually cause the entire protein to divide itself. b. Lipids: The lipids in the membrane of the cell are altered by sickle cell disease. Those who suffer from the disease have defective fasting lipid metabolism. This has
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CDC‚ sickle cell disease is a hereditary disease where the red blood cells have an unusual shape that prevents them from moving easily through the blood vessels and satisfying their metabolic needs causing them to die faster. People with sickle cell disease often experience pain due to the sickle cell blocking the small blood vessels‚ anemia due to the low healthy blood cell count‚ and infections. Although it is impossible to obtain accurate information about everyone that has the sickle cell disease
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Anemia is a deadly disease; approximately 50% of people with sickle cell anemia survive to mid-40’s although fewer than 10% live more than 60 years. The devastating thong about anemia is that it can be inherited and with no cure‚ the cases of Anemia are increasing. Even though there is no cure‚ early diagnosis of low blood count can lead to better treatment‚ with better treatment‚ patients can live normal lives. However‚ the key to early diagnosis is learning what anemia is and the causes of this
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Anemia Anemia is usually defined as a decrease in amount of red blood cells (RBCs) or the amount of hemoglobin in the blood. It can also be defined as a lowered ability of the blood to carry oxygen. When anemia comes on slowly the symptoms are often vague and may include: feeling tired‚ weakness‚ shortness of breath or a poor ability to exercise. Anemia that comes on quickly often has greater symptoms which may include: confusion‚ feeling like one is going to pass out‚ and an increased desire to
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Anemia ABSTRACT The purpose of this paper is to briefly describe the initial core diagnostic questioning and core set of diagnostic testing related to the patient presenting with anemia. Subjective information and recommended testing are written with consideration of the scope of practice of the family nurse practitioner. In addition‚ three specific case studies are examined. Anemia Core set of subjective questions The healthcare provider should initially obtain a history of any previous
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understand that proteins and DNA are not just abstract concepts in biology textbooks but rather crucial components of our bodies that affect familiar functions and characteristics. Key Concepts: • Proteins are responsible for many important aspects of cell structure and function. • Differences in the structure and function of proteins result in differences in the characteristics of biological organisms. Teaching Approaches: 1. Brainstorming session using the probe "What are proteins? Why are
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Anemia A blood type is a classification of blood based on the presence or absence of inherited antigenic substances on the surface of red blood cells (RBCs). These antigens may be proteins‚ carbohydrates‚ glycoproteins‚ or glycolipids‚ depending on the blood group system. Some of these antigens are also present on the surface of other types of cells. Some of these red blood cell surface antigens can stem from one allele and collectively form a blood group system. It is called The ABO system and it
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done to “cure” other blood disorders and what preventive measures need to be taken in order to stop history from repeating itself. Iron deficiency anemia‚ sickle cell anemia‚ and purpura simplex are just a few blood disorders that people suffer from that are either inherited or can be prevented. Iron deficiency anemia‚ one of the most common types of anemia‚ is a blood disorder where the body does not absorb enough iron for proper function (HealthCentral Network‚ 2010). If the body is not getting enough
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