Cell‚ Vol. 116‚ 769–778‚ March 19‚ 2004‚ Copyright 2004 by Cell Press Socializing with the Neighbors: Stem Cells and Their Niche Elaine Fuchs‚* Tudorita Tumbar‚ and Geraldine Guasch Howard Hughes Medical Institute The Rockefeller University New York‚ New York 10021 Review The potential of stem cells in regenerative medicine relies upon removing them from their natural habitat‚ propagating them in culture‚ and placing them into a foreign tissue environment. To do so‚ it is essential to
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STEM CELLS® TISSUE-SPECIFIC STEM CELLS Current Concepts in Bone Marrow Microenvironmental Regulation of Hematopoietic Stem and Progenitor Cells Julianne N. P. Smith and Laura M. Calvi Key words. Adult haematopoietic stem cells Bone marrow Bone marrow stromal cells Hematopoiesis Hemopoietic stem cells Osteoblast Stem cellmicroenvironment interactions Endothelial cell ABSTRACT “Within the microanatomy of mammalian bone‚ hematopoietic stem and progenitor cells (HSPCs) interact with numerous
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Stem Cell Culture Human embryonic stem cells are pluripotent stem cells derived from the inner cell mass of the blastocyst‚ an early-stage embryo. To culture these stem cells under controlled environments‚ one first must have a growth medium. This growth medium is made with DMEM/F12‚ which is cell culture medium‚ a 20 percent Knockout Serum Replacement‚ 100 μM β-Mercaptoethanol‚ 1 percent non-essential Amino Acid‚ and a Basic Fibroblast Growth Factor. This medium is then changed out everyday
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Ethics Behind Stem Cell Research. Is Stem Cell Research ethical? Yes‚ it is. An embryo which is four or five days old‚ from which stem cells are derived‚ is not a human being yet‚ because it’s brain is nonfunctional and it’s heart is not beating. So destroying it would not be murder‚ it’s just a beginning of a long process of obtaining stem cells from it. Ronald Reagan‚ The Ethics Committee of the American Society for Reproductive Medicine‚ Christopher Reeve‚ Michael J. Fox and various writers
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advancing‚ every day we learn more about how life works and through this we increase our knowledge and understanding of health and disease. Even in the last ten years we have had numerous scientific advancements‚ from the human genome project to stem cell research. I hope to one day contribute to this understanding through the knowledge and skills I gain from this course. I have always had an interest in science‚ especially in terms of how illness and disease affects the body. I developed an interest
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A01: Examine any four of Fletcher’s six fundamental principles of Situation Ethics By Saskia Hallam The first principle of Fletcher’s which I will examine is that Fletcher says ‘only one thing is intrinsically good‚ namely love: nothing else at all.’ Using this principle Fletcher is explaining how only love is good in itself. He uses the principle to explain how nothing else has intrinsic value as other actions ‘gain or acquire their value only because they happen to help people‚ therefore being
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Stem cell research is a new technique developed to extract stem cells from human embryos and aborted fetuses. Stem cells are cells from a human organism which are capable of becoming many different kinds of human tissue in the body. Stem cells‚ specifically‚ are cells that have not been fully differentiated as particular cells and can potentially become any tissue in the human body. The major purposes or goals of doing stem cell research are to gain scientific knowledge about embryonic development
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Stem cell research is often at the forefront of heated ethical debates due to its assessment of human life. If stem cell research cannot be ethically defended‚ then it should not be conducted. “You cannot defend a study ethically unless the presumed cost is lower than expected benefits. The cost-benefit analysis of scientific research needs to include human/animal discomfort/risks‚ environmental issues‚ material costs‚ etc” which is necessary to support the positive outcome which the research claims
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life via new research. One of the recent biomedical research is “Human Stem Cell” from which all 210 different kinds of tissue in the human body originate(the Center for Bioethics and Human Dignity‚ 94). Additionally‚ UNESCO states that separating some inner cell mass from the embryo at the blastocyst stage‚ they can be cultured to produce pluripotent stem cells‚ capable of developing into blood ‚ muscle‚ or many other kinds of tissues and organs of the body (13). Thus‚ at first “Stem Cell” may sound
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Biology 103 Stem cells are known as the foundation of our bodies‚ and without them we would be unable to repair various organs or tissues whenever they may become damaged. Stem cells are very extraordinary cells because after division and a new cell is created‚ they are able to either remain a stem cell or turn into an even more specialized cell such as a muscle cell‚ red blood cell‚ or brain cell. Until recently‚ there were only two major types of stem cells‚ known as embryonic stem cells and adult
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