Introduction Graft-versus-host disease (GVHD) is often a much too frequent complication of allogeneic Bone Marrow Transplants (BMT). Bone marrow transplants are given to treat malignant and nonmalignant diseases such as leukemia‚ lymphoma‚ marrow failure also known as aplastic anemia‚ metabolic disorders‚ HIV‚ Inherited red cell disorders (Gratwohl‚ 2006). Bone marrow can be taken from umbilical cord blood‚ peripheral blood stem cells and from bone marrow itself from various donors. They can
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Case Study 1 1. Briefly describe the three major layers of skin that make up healthy skin The three layers that make up healthy skin: Epidermis‚ Dermis and Hypodermis. Epidermis is composed of keratinized‚ stratified squamous epithelium. This layer provides a thick‚ water proof protective covering over the underlying skins. The dermis layer is composed of primarily of dense‚ irregular‚ fibrous connective tissue that is rich in collagen and elastin. The dermis contains blood vessels‚ nerve ending
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Case Study #2 1. Epidermis: Is the top layer of the skin. It is made up of stratified squamous cells called keratinized cells. The top layer is dead keratinocyte. Dermis: Is the middle layer of skin. This is where skin gets its color. Melanin‚ hemoglobin‚ and carotene are located here. Also many glands are in the dermis such as sweat glands‚ oil glands‚ hair/hair follicles‚ nails. Hypodermis: is the bottom layer of the skin. It contains adipose tissue‚ fat‚ and blood vessels.
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In earlier days‚ a burn victim was treated with skin graft from unharmed part of the body‚ which if not available‚ a section of skin was obtained from a donor preferably a cadaver. This was basically done because unlike most wounds‚ skin damaged from thermal injuries can never repair themselves and to make the matter worse‚ a person can die from the accident due to loss of plasma and from infection. The latter source of allograft often led to rejection by the recipient’s immune system. So‚ in case
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Skin Disorder: Vitiligo Vitiligo is a skin condition whose exact cause is unknown. In vitiligo‚ patches of skin lose their pigmentation when the pigment producing cells‚ the ’melanocytes’ are attacked and destroyed. It may affect the skin‚ mucous membranes‚ eyes‚ inner ear or hairs leaving white patches. The usual type of vitiligo is called ’Vitiligo Vulgaris’ (means: common vitiligo). Variant types include linear‚ segmental‚ trichrome and inflammatory vitiligo. This disease affects an estimated
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areas of the body that undergo more abrasion (Epithelial Cells) than then areas of the body that require just having simple squamous epithelium (Epithelial Cells). Examples of areas that need stratifies squamous epithelium are the outmost layer of skin as well as the lining of the mouth and esophagus. In contrast‚ areas that use simple squamous epithelium include capillaries‚ alveoli‚ and various tissue that require rapid diffusion. 2. List and explain the different characteristics of each membrane
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What is Epidermolysis Bullosa? Epidermolysis Bullosa (EB) is the term used to describe a genetically-determined skin disorder. It is a group of blistering skin conditions where the skin is so fragile in people with EB that even minor rubbing may cause blistering. All forms of EB are genetic in origin and the genes responsible for most of the sub-types of the condition are now known. It is estimated that 2 to 4 out of every 100‚000 people‚ or up to 12‚000 people in the United States‚ have some form
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Burns Burns Burns are injuries to either skin (caused by heat‚ electricity‚ or chemicals)‚ or respiratory tract (caused by inhalation of smoke or hot particles). According to the CDC someone in the United States sustained burn injuries every 30 minutes (CDC‚ 2013). Pathophysiology The cell and tissue damage noted in burns is a result of exposure to temperatures above 44⁰C‚ which cause proteins to denature (Hettiaratchy & Dziewulski‚ 2004). This breakdown causes tissue necrosis; the necrotic
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System Introduction I. Skin and Its Tissues A. Introduction 1. The skin is composed of several kinds of tissues. 2. Skin is a protective covering that prevents many harmful substances from entering the body. 3. Skin also retards water loss and helps regulate body temperature. 4. Skin houses sensory receptors and contains immune system cells. 5. Skin synthesises vitamin D and excretes a small amount of waste products. 6. The two distinct layers of skin are epidermis and dermis
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A Psychological Report showing the effects of differing sounds on Galvanic Skin Response‚ Respiration and Heart Rate | | By Eunan McCloskey | 12/11/2009 | | Table of Contents Title Page....................................................................................................................................1 Table of Contents.......................................................................................................................2 Abstract.................
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