The Jenner Trial "The smallpox was always present‚ filling the churchyards with corpses‚ tormenting with constant fears all whom it had stricken‚ leaving on those whose lives it spared the hideous traces of its power‚ turning the babe into a changeling at which the mother shuddered‚ and making the eyes and cheeks of the bighearted maiden objects of horror to the lover" (Macaulay). Imagine walking down the busiest street in 1700s London‚ and you only saw a dozen people. In every window‚ bodies
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invent successful vaccination (in this case for smallpox.) At the time‚ smallpox was a greatly feared disease. One in three of those who caught it died and any survivors were often badly disfigured. He investigated the rural old-wives tale that milkmaids couldn’t get smallpox believing there to be a connection. After examining a woman with cowpox‚ he noticed she had blisters on her hands and concluded it was the pus in them that prevented smallpox. James Phipps‚ a young boy‚ volunteered to be Jenner’s
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the development of the smallpox vaccine. Smallpox was an ancient yet deadly disease that spread rapidly and impacted every class in society starting from the times of the Egyptians in 1570 BC. It was considered to be the most feared and likely the greatest killer during his time‚ killing up to 33% of those who contracted it worldwide. This was the first vaccine to ever be created successfully‚ saving countless lives in the process‚ eventually leading to the end of smallpox. Born in the small village
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but every bit as horrifying as anthrax is smallpox. Smallpox is an acute‚ highly contagious virus disease characterized by prolonged fever‚ vomiting‚ and pustule eruptions that often leave pitted scars‚ or pockmarks‚ when healed as defined by Webster’s New World College Dictionary. Smallpox‚ commands respect and the concern of the American public along with that terrorism‚ of the biological variety‚ however improbable‚ is very possible. At onetime smallpox was once large academic before vaccinations
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infect the people of Mantua with swamp fever during his Italian campaign (“biological warfare”). During the French and Indian War in the 18th century AD‚ British forces under the direction of Sir Jeffrey Amherst gave blankets that had been used by smallpox victims to the Native Americans in a plan to spread the disease (“History of Biological Warfare”). A more recent example of biological weapons was in 1995. A Japanese terrorist group‚ called Aum Shinrikyo‚
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world’s most lethal emerging viruses‚ has ORCON security clearance that gives him access to top secret information on bioweapons. His most urgent priority is to develop a drug that will take on smallpox--and win. Eradicated from the planet in 1979 in one of the great triumphs of modern science‚ the smallpox virus now resides‚ officially‚ in only two high-security freezers--at the Centers for Disease Control in Atlanta and in Siberia‚ at a Russian virology institute called Vector. But the demon in
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discusses the anthrax terrorist attacks after 9/11 and how smallpox might become a future bioterrorist threat to the world. The book provides a brief history of the smallpox disease including details of an outbreak in Germany in 1970. The disease was eradicated in 1979 due to the World Health Organization’s aggressive vaccine program. After the virus was no longer a treat the World Health Organization discontinued recommending the smallpox vaccination. In conjunction‚ inventory of the vaccine was
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Class: Orthopoxvirus Genus : Poxvirus species: Smallpox (Variola) Special physical structures • Double-stranded DNA virus • Linear molecular structure with complex morphology • Unique enveloped large brick shaped • Obligate Intracellular Parasite Unusual genes or toxins • Poxvirus is one of the largest viruses that contain several subfamilies such as cowpox‚ monkeypox‚ vaccinae‚ orf and molluscum to name a few with smallpox being the most endemic of all •Poxvirdae is one of
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CHAPTER 6 Smallpox: A Primer Brenda J. McEleney Smallpox‚ is a virus that plagued humanity for millennia. It was the first and only disease ever intentionally eradicated from the face of this planet‚ a scourge defeated in a remarkable‚ never-before-attempted campaign of generosity and cooperation by the nations of the world. Its eradication was a triumphant symbol of science and dogged persistence winning over nature. Moreover‚ its eradication was a gift of man to all mankind. Yet‚ is it possible
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The most known member of the Poxviridae family is variola virus‚ the causing agent of smallpox disease. From the time of its suspected emergence after 10‚000 BC to the time of its eradication‚ smallpox was a worldwide feared disease that took hundreds of millions of lives (8). The first recorded smallpox epidemic was in 1350 BC during the Egyptian–Hittite war. Smallpox then spread to Europe between the 5th and 7th centuries and to the North American colonies during the 17th and 18th centuries. These
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