Coagulation factor V (FV) circulates in the bloodstream in an inactive form (procofactor) and is activated to factor Va (FVa) by thrombin. Thrombin cleaves away the large inhibitory B-domain of FV which resolves the molecule into a heterodimer that is stabilized through non-covalent interactions between heavy (A1-A2) and light (A3-C1-C2) chains. A recombinantly expressed truncated B-domain variant of factor V (FV-DT) exhibits constitutive FVa-like activity even in the absence of proteolysis. FV maintains
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Henry V – William Shakespeare There can be little doubt that Shakespeare intended to present his protagonist in “Henry V” as the popular hero-king. His efforts are mainly concentrated on the portraiture of this “star of England”‚ King Henry‚ whom he deliberately chose out of the page of history as the finest representative of the best distinctive type of English character. He wanted his play to lead triumphantly to an English victory against overwhelming odds at Agincourt. What is not agreed among
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Case Name: Missouri v. Jenkins 491 U.S. 274 (1989) United States Supreme Court Facts: The attorneys and associates for plaintiff‚ Kansas City Missouri School District‚ had been litigating a school district segregation case since 1979 and NAACP had been litigating the case since 1982. Attorneys asked and received reasonable attorney fees under Civil Rights Attorney’s Fees Awards Act of 1976‚ 42 U.S.C. §1988. All fees were given at current market rates. A Court of Appeals affirmed this
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saw some of the most important cases in the history of the United States and many are still in effect today. The Warren court heavily believed in improving the civil liberties of the people. His ruling on Gideon v. Wainwright is no different. In 1963‚ the monumental case of Gideon v. Wainwright was taken to the Supreme Court. This case involved the 6th amendment of the constitution. The case began as a simple accusation of Gideon of a burglary in Panama City‚ Florida. After being accused‚ Mr
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The poem‚ "The Fish Are All Sick" by Anne Stevenson‚ speaks a lot about the relationship between humans and nature‚ specifically the marine ecosystem‚ in the world today. Looking closely at the title of the poem‚ it seems that the poem is fictional - we usually hear fishes getting sick in fictional literary pieces. In addition to that‚ the use of the word "all" is an exaggeration of the dramatic situation of the poem - fishes are all sick. And the fact that it goes on to saying that whales are dying
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The conclusion of Scott v. Sandford was considered the worst judgment Chief Justice Roger broke Taney ever composed. He disregarded constitutional points of reference‚ misshaped history‚ forced an inflexible instead of an adaptive development on the constitution‚ overlooked particular awards of power in the constitution‚ and tormented implications out of other‚ more-cloud provisions. His rationale on the citizenship issue was maybe the most convoluted. He conceded that African Americans could be
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MBA560 COUGHLIN v TAILHOOK 112 F.3d 1052 (1997) United States Court of Appeals‚ Ninth Circuit Facts: During a convention at the Las Vegas Hilton in September 1991‚ Navy Lieutenant Paula Coughlin was attacked by a group of men in a hotel hallway. The resulting post-traumatic stress disorder and other problems related to the attack eventually hampered her ability to perform her duties. Ultimately‚ she resigned from the US Navy. Coughlin brought action against the Hilton Hotels Corporation
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Miranda V Arizona In the history of the United States‚ the legislative branch of government has developed systems of laws which the judicial branch of government checks. Because of modernization‚ the constitutionality of these laws needs to be reevaluated from time to time. There have been many cases that have caused the government to amend certain laws to protect its citizens. One of the most important cases that was brought to the Supreme Court was the case of Ernesto Miranda V the state of
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Henry and Prince Hal’s discussion on what makes a great king. Like a comet‚ the less is seen of the king‚ the more of a sovereign‚ enigmatic figure he becomes and the more respect he gains when he makes such seldom appearances.) Henry V (In the final act of Henry V‚ Henry approaches Princess Catherine of France to try and woo her. He makes it seem as if he is a lovestruck‚ simple man that isn’t very good with words (even though the reader know that this is certainly not the case). The reader knows
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violated the First Amendment. In trying to keep minors away from inappropriate material the Act reduced "the freedom of speech" by restricting what adults could send over the internet. # 2) Legal Precedent: a. Sable Communications of California v. FCC (1989) was in response to a ban on indecent and obscene interstate commercial phone messages. Sable Communications was in the dial-a-porn business. The supreme court decision was that the ban on obscene speech was valid since the constitution does
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