Cell injury In this topic we are going to cover Cell injury Causes of cell injury Mechanism of cell injury Morphologic alterations in cell injury Morphologic types of necrosis Objectives Describe cell injury List the causes of cell injury Discuss how depletion of ATP causes cell injury Describe how mitochondrial damage cause cell injury Explain the mechanism of cell injury by free radicals Discuss how calcium ion influx cause cell injury Cell injury cell injury results when cells
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AP* Chemistry ELECTROCHEMISTRY Terms to Know: Electrochemistry—the study of the interchange of chemical and electrical energy OIL RIG – oxidation is loss‚ reduction is gain (of electrons) Oxidation – the loss of electrons‚ increase in charge Reduction – the gain of electrons‚ reduction of charge Oxidation number – the assigned charge on an atom Oxidizing agent (OA) – the species that is reduced and thus causes oxidation Reducing agent (RA) – the species that is oxidized and thus causes reduction
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Topic 2 – Cell membranes Reading Chapter 5 Objectives Functions of cell membranes The fluid mosaic model The lipid bilayer – phospholipids‚ glycolipids and sterols Properties of the lipid bilayer Membrane proteins – the ‘mosaic’ in the model Solute movements across membranes BIO 1140 – SLIDE 1 http://www.nikonsmallworld.com/gallery/year/2006/id/751 Functions of cell membranes – an overview Fluid mosaic model Singer & Nicolson 1972 Fluid lipid molecules in which
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osmotic pressure as the amount of pressure required to contain a specific volume of fluid in a container. Both pressures are external. 4. Describe a situation that demonstrates diffusion and a situation that demonstrates osmosis occurring either in the human body or in the environment. Answer: Diffusion is molecules moving from an area of high concentration to an area of low concentration. For example‚ ammonia molecules have a powerful odor. When a stopper is removed from a beaker containing ammonia‚
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SPECIALIZED CELL ANIMAL Sperm cells PLANT Xylem cells are specialised to find a female cell (egg cells) and join with it. They have tails‚ that makes them move in water to find and fertilize the female cell. They can move because they have many mitochondria located between the tail and the head‚ which gives them energy. In the head‚ there is a vacuole filled with acrosome‚ which is a specialized Lysosome that releases enzymes in order for the Sperm Cell to break into the Egg Cell‚ through the
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Cell Structure and Function Chapter Outline Cell theory Properties common to all cells Cell size and shape – why are cells so small? Prokaryotic cells Eukaryotic cells Organelles and structure in all eukaryotic cell Organelles in plant cells but not animal Cell junctions History of Cell Theory mid 1600s – Anton van Leeuwenhoek Improved microscope‚ observed many living cells mid 1600s – Robert Hooke Observed many cells including cork cells 1850 – Rudolf Virchow
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7/6/2011 CELL DIVISION CHAPTER 3: CELL DIVISION 3.1 THE CONCEPT OF CELL DIVISION 3.2 THE CELL CYCLE 3.3 MITOSIS 3.4 MEIOSIS Related to the theory of cells Rudolph virchow ; 1855 stated; „Omnis cellula e cellula‟ Every cell is from a cell or “All new cells are derived from other cells” A cell (daughter cell) is originated from another cell ( ) through . In cell division‚ is inherited from one generation to the next. Involve the distribution of genetic material (DNA) to each daughter
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CELL INJURY: CAUSES OF CELL INJURY‚ MECHANISMS OF REVERSIBLE AND IRREVERSIBLE CELL INJURY. CELL INJURY. Causes of cell injury range from gross mechanical external causes to mild endogenous causes as genetic lack of enzymes etc. Virtually all forms of tissue injuries start with molecular or structural alterations in cells. Under normal conditions‚ the cells are in: ❖ homeostastatic „steady“ state Normal cell is confined to relatively narrow range of functions and structure by
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DESCRIBE THE STRUCTURAL COMPARTMENTATION OF MAMMALIAN CELLS AND THE DIFFERING FUNCTIONS OF THESE COMPARTMENTS? Mammalian cells are eukaryotic this means that all of their cells have common components‚ membrane bound organelles which prokaryotic cells do not this is shown in figure 1. Organelles are purpose made to carry out a specific function that is necessary within a cell. Due to the specificity of both conditions and concentrations with in these organelles these are compartmentalized. Encasing
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The cell wall is the tough‚ flexible but sometimes fairly rigid layer that surrounds some types of cells. It is located outside the cell membrane and provides these cells with structural support and protection. Just as the wall of the factory is for the factory. The wall also is the structure and strength. The cell membrane that separates the interior of all cells from the outside The cell membrane is selectively permeable to ions and organic molecules and controls the movement of substances
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