Microscale Crystallization of Sulfanilamide Purpose The purpose of the experiment was to use the crystallization technique to purify the solute sulfanilamide using 95% ethanol as the solvent‚ to calculate the amount of sulfanilamide that was recovered‚ and to determine the purity of the final product. Introduction In this experiment‚ recrystallization will be the method used to purify the solute sulfanilamide using ethanol as the solvent. Based on the solubility curve on the solubility
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Microscale Crystallization – Craig Tube For this experiment‚ we had to find the percent recovery and melting point of pure sulfanilamide from impure sulfanilamide using the crystallization technique. To start‚ .1004 grams of impure sulfanilamide was put into a Craig tube with enough ethyl alcohol to barely pass the top of the sulfanilamide. The Craig tube was put into a stone block until boil‚ then check to see if the solid material had dissolve. With the addition of two more drops from a supply
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Sulfa Drugs: Preparation of Sulfanilamide Introduction The purpose of this experiment is to prepare sulfanilamide from p-Acetamidobenzenesulfonyl chloride. This will be done using reflux‚ vacuum filtration‚ and melting point determination. Experiment Scheme6 Figure 1. Reaction equation.6 A hot water bath was prepared in a fume hood using a 250-mL beaker. 2.5 g of p-acetamidobenzenesulfonyl chloride was placed into a 50 mL Erlenmeyer flask and 11 mL of dilute ammonium hydroxide solution
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folic acid‚ PABA inhibitors such as sulfanilamide selectively kill bacteria without injuring the host (Figure 1). One of the most well-known preparation techniques of sulfanilamide is achieved by treating aniline with excess chlorosulfonic acid via replacement of hydrogen with a sulfonyl chloride group. This reagent forms sulfonic acid first before being converted into a sulfonyl chloride by the excess chlorosulfonic acid (Scheme 1). A key method of sulfanilamide production via this chlorosulfonic
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Introduction: Sulfa drugs are any member of a group of synthetic antibiotics containing the sulfanilamide molecular structure (Figure 1). Sulfa drugs were the first class of antibiotics to treat and prevent bacterial infection in humans. Sulfa drugs have been used less frequently due to improved antibiotics that are more effective‚ have less side effects‚ and decreased drug resistance.1‚ 2 Sulfonamides are still used today as an anti-bacterial medication and for the prevention of burns. The antibacterial
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stated that dissolving the sulfanilamide would take no longer than 15 minutes. It took us almost two hours. This could be due to the fact that we did not have the hot plate at the proper temperature to begin with‚ in order to dissolve the sulfanilamide. The amount of time it took to dissolve the sulfanilamide made me think that we did something wrong and our results would not be accurate. Crystallization: Part B: Start Finish % Recovery Expected Remaining Sulfanilamide 0.093g 0.059g 68.6% 0.034g
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Antibiotics The term anti biotic is defined as a drug derived from living matter or micro organism. Which either prevents the growth of other micro organism or destroy them. Classification * The spectrum of biological action of anti biotic * It mainly effective against gram positive bacteria. Eg.penicillin‚fucidin * It mainly effective against gram negative bacteria . E.g. strepomycin * It effective against protozao. Eg
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treatments‚ the nature of the product they provide - drugs and by association good-health – has left them open to damning criticism. This essay shall examine one of the primary roots of such criticism; the drug scandal. By studying the cases of Sulfanilamide and Ritalin‚ this essay shall determine why such scandals have occurred throughout the century despite dramatic legal changes. Ultimately‚ this essay hopes to chart the evolution of such drug scandals‚ and the complex relationships therein‚ between
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To what extent did medical advancements during world war two impact the lives of soldiers? One may argue that one of the most helpful drugs during word war two‚ penicillin‚ was discovered in 1960‚ prior to world war two. Although penicillin wasn’t discovered during world war two‚ it was improved on many levels during the time such as production on an industrial scale‚ it became much more readily available‚ and by 1945 it was 20 times stronger than the 1939 version of penicillin. Therefore‚ even
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Lab 3: Crystallization Report Objective: the objective of this lab is to introduce the technique of crystallization. Background: The chemicals used in part A were Sulfanilamide and Ethyl alcohol. Sulfanilamide(C6H8N2O2S)‚ or sulfonamide antibiotic‚ functions by competitively inhibiting enzymatic reactions involving para-aminobenzoic acid (PABA). PABA is needed in enzymatic reactions that produce folic acid which acts as a coenzyme in the synthesis of purine‚ pyrimidine and other amino acids
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