INTRODUCTION A major obstacle in the successful treatment of cancer is the development of resistance mechanisms to drug treatment. Various cellular changes that have been implicated in the development of drug resistance in cancer cells include: the increased expressions of P-glycoprotein (a multidrug transport protein) and multidrug resistance-associated protein (MRP-1); increased levels of the cellular detoxification protein‚ glutathione; and changes in the expression of apoptosis associated
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of a Wire Affects Its Resistance In my physics coursework I am going to investigate the effect of the length of a wire on its resistance. Resistance is the measure of how easy it is for current to flow through a wire. Current is the rate of flow of charge through a conductor‚ and it is measured in amps using an ammeter. To help me plan my investigation I have completed a preliminary experiment in which I investigated the effect of the thickness of a wire on its resistance‚ using three constantan
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“Liberty‚ Property‚ Security‚ and Resistance to Oppression” In recent times‚ France has experienced monumental events that foreshadow quite a different future for France‚ and the beginning of a new revolutionary regime. Disorder and theft have unfortunately accompanied violent events and in response: the formation of the National Guard. The Guard is composed of professional soldiers‚ foreign mercenaries‚ merchant and shopkeepers’ sons‚ and sons of the most comfortable master workers and journeymen
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Current is a flow of electrical charge carriers‚ usually electrons or electron-deficient atoms. The common symbol for current is the uppercase letter I. The standard unit is the ampere‚ symbolized by A. One ampere of current represents one coulomb of electrical charge (6.24 x 1018 charge carriers) moving past a specific point in one second. Physicists consider current to flow from relatively positive points to relatively negative points; this is called conventional current or Franklin current. Electrons
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Health Care Support Services HCS/212 December 10‚ 2012 Health Care Support Services The experience I have encountered so far in the health field has been doing medical billing. In billing for claims through a facility or provider you deal with all kinds of insurance programs. Out of all the different health care programs Medicare or a Medicare supplement is about eighty percent of my medical billing. There are things about how Medicare that I do not understand or feel that their decisions
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& Genetics 5 Landecker‚ Hannah Flaherty‚ Devin October 25‚ 2012 Testimony 1 Good Afternoon‚ Congress. Thank you for inviting me to discuss the significant issues and possible actions that can be brought to the antibiotic resistance issue. My name is Dr. Joe. I am a professor of professor of Society and Genetics. Through the research facilities at the university‚ I cultivate bacteria and observe what harms or benefits the different species are. For years‚ I focused my research
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Everyone has different viewpoints and opinions‚ so what seems just to one person might be deemed as unfair to another. During times of disagreement it is best to have peaceful resistance because this prevents mass violence from arising while still promoting a different opinion to be taken into consideration. Resistance has had a major impact in our society as it has lead to revolutions and laws to help establish more freedoms and fairness. For instance‚ during the 1880’s the Jim Crow Laws were
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Leadership and Peer Support Final Reflection Guide Mihalitsa Hatzisavvas At the beginning of this year I had no idea which class I wanted to take last. I had not many options‚ I went from Law to English to Media then I was just going to take a spare. One day as I was walking down to my next class I heard Mr.Karr talking about the Leadership class and how it only had one student
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1. Rank these 7 benefits in importance (from most to least) for reducing user resistance to IT-based change giving your reasons. 1. Develop Stakeholder Relationships That Support theProject’s Success We have to have a good relationship among the team members and the PM also with the stakeholders.the stronger relationship that we have the strong support and information we will get‚ to make the best decision . 2. Cast a Vision for Shared Project Objectives That Will Attract‚ Inspire‚ and Motivate
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EM6 INTERNAL RESISTANCE AND EMF OF A BATTERY CELL DCP ASPECT 1 SYMBOLS: Internal resistance of the battery: r External variable resistor: R Voltage: V EMF of the battery: E Current: I FORMULA V= IR E = I (R+r) E = IR +I ⋅ r E = V + I ⋅ r V = E - I ⋅ r V = -r ⋅ I +E _Graph of V against I will be plotted in order to_ _determine the internal resistance and EMF of the battery. The slope will be -r and the intercept vertical axis will be the EMF (E)._ REFERENCE VALUE EMF of the battery
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