The nonmutated form of DMPK functions in the production of protein kinase serine; this enzyme plays a role in intracellular communication and in the regulation of myosin phosphate. When DMPK is mutated‚ the proteins CUG-BP1‚ MBNL1 and INSR are displaced causing the splicing of troponin pre-mRNA which causes malfunctions in the cardiac conduction system‚ dominance of a chloride channel that causes myotonia‚ dominance of an insulin receptor that affects the sufficiency of insulin‚ and dominance of
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Introduction: The pharmacokinetics of a drug describes the journey of a drug through the body i.e. its absorption‚ bioavailability‚ distribution‚ metabolism and excretion. Opioids are substances (endogenous or synthetic)‚ which produce ‘opiate-like effects’. Opiates are alkaloids derived from the Papaver somniferum poppy e.g. Morphine‚ Codeine (a morphine-like agonist) and Methadone (a synthetic analogue of morphine) and are primarily used as analgesics.[1] Discussion: Morphine has a 4-ring structure
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purpose of a synthesis essay is to make insightful connections. Those connections can show the relationship(s) between parts of a work or even between two or more works. It is your job to explain why those relationships are important. In order to write a successful synthesis essay‚ you must gather research on your chosen topic‚ discover meaningful connections throughout your research‚ and develop a unique and interesting argument or perspective. A synthesis is not a summary. A synthesis is an opportunity
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Problem Formulation and Identification Paper (Your Name) (Instructor ’s Name) (Class Name/#) (Date) Problem Formulation and Identification Paper Burgess (1998)‚ “organizations are often structured in ways which empower a single individual or small group to make key decisions. In democratic systems‚ these decision makers are usually expected to obtain advice from affected parties and then make a decision which advances the interests of the whole organization while fairly resolving competing
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Protein Synthesis Worksheet 1. 2. a. Protein synthesis began in the nucleus. b. Chromatin is a diffuse mass located in the nucleus where genetic material is found. c. A gene is a sequence of nucleotides‚ it is important because they form the template and these templates are used for synthesizing proteins. 3. a. Transcription is the first step of protein synthesis it uses a sequence of DNA nucleotides to produce a sequence of RNA nucleotide. b. RNA polymerase bonds to RNA nucleotides together
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The Grignard Synthesis of Triphenylmethanol Abstract: Grignard synthesis of triphenylmethanol was achieved by use of the Grignard reagent phenyl magesium brominde. The organometallic grignard reagent was synthesized by use of a reflux apparatus recrystallization techniques. Once synthesized it was used in a Grignard reaction that involved nucleophilic addition to a carbonyl in order to make triphenylmethanol. The final product was solidified and recrystallized and spectral data was
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Synthesis of Aspirin and Tylenol Kyla Wykoff Abstract Aspirin and Tylenol were synthesized by means of crystallization‚ recrystallization‚ and melting point determination. Synthesis produced significantly high percent yields for aspirin‚ however‚ produced extremely low and impure percent yields for Tylenol. A second group was also used to compare results and errors‚ in which they too were also producing extremely low percent yields of Tylenol. Therefore‚ error was based on the specific protocol
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ACCOUNTING 505 SYNTHESIS |Key Features of a Synthesis | (1) It accurately reports information from the sources using different phrases and sentences; (2) It is organized in such a way that readers can immediately see where the information from the sources overlap;. (3) It makes sense of the sources and helps the reader understand them in greater depth. |The Background
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0.22g (percent yield of 86.9%). The percent yield after recrystallization‚ was 80.9%. INTRODUCTION The goal of this experiment was the synthesis of 3-nitrochalcone from 3-nitrobenzaldehyde and acetophenone as shown in Figure 1: Figure 1: Synthesis of 3-Nitrochalcone from 3-Nitrobenzaldehyde and Acetophenone Source: cnx.org The mechanism for the synthesis of 3-nitrochalcone is presented in Figure 2. The alpha carbon on the acetophenone is deprotonated‚ followed by the attack of the alpha carbon
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Identification of Macromolecules Introduction The purpose of this lab is to test for the presence of macromolecules in various foods. Tests are performed to describe the basic structure of proteins‚ lipids‚ glycerides‚ and carbohydrates. We are to recognize the positives and negatives in these macromolecules. Also we are to identify the roles that proteins‚ lipids‚ minerals‚ vitamins‚ and carbohydrates play in the body’s construction and metabolism. Procedure / Results 5.1 Carbohydrate
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