Pat 1 Synthesis of 4-aryl-6-indolylpyridine-2-carbonitriles and evaluation of their biological activity Synthesis of 6-indolyl-4-aryl-3-cyanopyridine-2-one (1a-e) Employing the MCRs approach and microwave irradiation‚ an equimolar amounts of aromatic aldehyde‚ 3-acetylindole‚ ethyl cyanoacetate were reacted with excess of ammonium acetate in one-pot‚ reaction‚ under the microwave irradiation‚ afforded a novel series of 4-aryl-6-indolyl-nicotinonitrile-2-one derivatives 1a-e. Ethylene glycol was
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Letters 2013‚ Volume 1‚ Issue 1 A Perkin Reaction: Synthesis of (E)- and (Z)-Phenylcinnamic acids Thusanth Jogarajah‚ Dr. Lana Mikhaylichenko * Department of Physical and Environmental Sciences‚ University of Toronto Scarborough‚ 1265 Military Trial‚ Scarborough‚ ON‚ M1C 1A4 Received: February 6‚ 2013; E-mail Thusanth.Jogarajah@mail.utoronto.ca Abstract – Add text here Introduction: The name of this reaction is called the Perkin’s reaction. The reaction was first used by William Perkin to
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Secondary excitotoxicity is thought to be more relevant to chronic neurodegenerative disorders than the classical acute form. In this pathway increased glutamate levels are not required as disturbances with the neuronal resting membrane potential cause glutamate receptors to be over-activated by physiological levels of glutamate. In a neuron which is affected by another pathological process and shows reduced ATP production‚ Na+ dysfunction or impaired glucose metabolism and as a result has an abnormal
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Duma’s method. The types of compounds that were used in testing were all functional groups‚ Aldehyde‚ Ketone‚ Alcohol and‚ Ester. Functional groups are a portion of a molecule that give the molecules its properties‚ they are the centers of chemical reactivity. The structures of the functional groups used in testing are displayed in Figure 1.0. Figure 1.0 Structure of Functional Groups to Distinguish from Within the
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EXERCISE 11 Synthesis of Aspirin (Acetylsalicylic Acid from Salicylic Acid) RAQUID‚ Rency J Group 5 18L I. Introduction Due to the demand of certain reagents in the laboratory in order to perform and conduct further experiments or produce essential compounds‚ chemists continuously develop organic synthesis. This process aims to prepare and synthesize desired organic compounds from commercially or readily available ones by providing the simplest route in synthesizing the compound
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Issue Investigation: Polyvinyl Chloride (PVC) Introduction: (Approximately 150 words) – KU3 · This investigation will be looking at the positives and negatives of using Polyvinyl Chloride (PVC)‚ and providing viewpoints on whether it is ethical to continue using this toxic plastic. PVC is a useful plastic‚ but can be harmful to humans and the environment. This plastic is used in medicinal tablet containers‚ to make bags for bedding‚ shrink wrap‚ deli and meat wrap‚ and tamper resistant lids
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“MOTIVATION” Filipino people are religious human being. We usually seek for guidance from our Lord in every decision we will made so in relation to that our teacher decided to have a speaker that can motivate us spiritually‚ emotionally and to enlighten us by a word of god. Fr. Joel Eslabra was the 1st invited speaker. He is a priest who is willing to share the word of God and also can give us inspiration. Fr. Joel starts his discussion with an inspirational lecture about the word of god presented
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Topic: 10-POINT AGENDAS OF PNOY REFLECTION: The Philippine Educational System is having some difficulties in resolving the different issues regarding the quality of education that we have today. Because of this‚ ‚His Excellency Benigno Simeon “Noynoy” Aquino our 14th President prioritized the upgrading of the educational system in our country. To give the Filipino people a good quality of education and for the Filipinos to be more globally competitive. One of his agenda is the
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To prevent the previously discussed risks related to the equipment and substances used in the synthesis reaction‚ safety procedures were discussed with the teacher‚ the fume cupboard was used‚ hands were washed‚ correct disposal procedures were followed‚ Disinfectant was used to wipe down benches‚ no flammable or loose clothing was worn‚ long hair was tied back‚ no naked flames were used‚ the safety shower and eye bath was available‚ first aid facilities were available‚ required spill management
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GRAVIMETRIC ANALYSIS OF A CHLORIDE SALT (2013) Report By: ____________ Lab Partner: ___________ Group: CHEM 1001 Tuesday AM‚ Group H Purpose: This lab was conducted in order to determine the content of chloride in an unknown salt‚ using gravimetric analysis. Theory: The salt chloride content is easy to find because it is slightly soluble‚ making it possible to turn it into a precipitate. A precipitate reaction can be done using silver
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